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Professor Liz Musgrove

 

Cancer Institute NSW Fellow; Senior Principal Research Fellow; Group Leader, Cancer Research Program, Garvan Institute of Medical Research; Conjoint Professor, Faculty of Medicine, The University of New South Wales

Email: e.musgrove 'at' garvan.org.au
Research Group: Cell Cycle

 
 

Education

1991 PhD, The University of New South Wales 
1979 BSc (Hons), The University of New South Wales

Publications

Musgrove EA, Sutherland RL. Biological determinants of resistance to tamoxifen treatment in breast cancer. Nat Rev Cancer 2009; 9(9):631-643.

Caldon CE, Sergio CM, Schutte J, Boersma MN, Sutherland RL, Carroll JS, Musgrove EA. Estrogen regulation of cyclin E2 requires cyclin D1, but not c-Myc. Mol Cell Biol 2009; 29(17):4623-4639.

Musgrove EA, Sergio CM, Loi S, Inman CK, Anderson LR, Alles CM, Pinese M, Caldon CE, Schutte J, Gardiner-Garden M, Ormandy CJ, McArthur G, Butt AJ, Sutherland RL. Identification of functional networks of estrogen- and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer. PLOS One 2008; 3(8):e2987.

Caldon CE, Swarbrick A, Lee CS, Sutherland RL, Musgrove EA. The HLH protein Id1 requires cyclin D1 to promote the proliferation of mammary epithelial cell acini. Cancer Res 2008; 68(8):3026-3036.

Butt AJ, Sergio CM, Inman CK, Anderson LR, McNeil CM, Russell AJ, Nousch M, Preiss T, Biankin AV, Sutherland RL, Musgrove EA. The estrogen and c-Myc target gene, HSPC111, is overexpressed in breast cancer and associated with poor patient outcome. Breast Cancer Res 2008; 10(2):R28.

Caldon CE, Lee CS, Sutherland RL, Musgrove EA. Wilms' tumor protein 1: an early target of progestin regulation in T-47D breast cancer cells that modulates proliferation and differentiation. Oncogene 2008; 27(1):126-138.

Caldon CE, Daly RJ, Sutherland RL, Musgrove EA. Cell cycle control in breast cancer cells. J Cell Biochem 2006; 97(2):261-274.

Swarbrick A, Akerfeldt MC, Lee CS, Sergio CM, Caldon CE, Hunter L-JK, Sutherland RL, Musgrove EA. Regulation of cyclin expression and cell cycle progression in breast epithelial cells by the helix-loop-helix protein Id1. Oncogene 2005; 24(3):381-389.

Carroll JS, Lynch DK, Swarbrick A, Renoir J-M, Sarcevic B, Daly RJ, Musgrove EA, Sutherland RL. p27Kip1 induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells. Cancer Res

Carroll JS, Swarbrick A, Musgrove EA, Sutherland RL. Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens. Cancer Res

Search for all publications by Liz Musgrove

 
 
 

Areas of Interest

cell cycle control, breast cancer, cyclins, estrogen, endocrine resistance
 

News

 

Calculating how breast cancers will respond to tamoxifen

MEDIA RELEASE: 08 Sep 2008
A discovery by Garvan scientists should help clinicians decide which women with breast cancer will make good candidates for anti-oestrogen therapies, such as tamoxifen, and which will not.
 
 

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