Professor Susan Clark Related News
Potential for earlier diagnosis of ovarian cancer
MEDIA RELEASE:
24 Jan 2012
Garvan scientists have identified biochemical changes that commonly occur in the DNA of women with ovarian cancer, which may help diagnose the cancer at an earlier stage in the future. The study used whole genome DNA profiling methods - locating six potential 'biomarkers', one of them a novel gene.
There is no such thing as identical where twins are concerned
MEDIA RELEASE:
12 Oct 2011
Identical twins have identical genomes, but that is where it stops. There are subtle differences in their personalities, how they look, how they act and in their susceptibility to disease. How can this be? It depends on exactly how specific parts of the genome are affected by ‘methylation’, or the attachment of hydrocarbon molecules - ‘methyl groups’, that literally change the voice of the genome, silencing some genes and amplifying others, say Garvan scientists.
Seminal shift in how we view cancer development
MEDIA RELEASE:
26 Jul 2011
Garvan researchers have uncovered a process that will bring about a fundamental shift in our view of the epigenetic processes that lead to cancer. Epigenetics involves biochemical changes in our bodies that directly impact our DNA, making some genes active, while silencing others. The current finding shows that a mechanism underlying one such epigenetic manoeuvre appears to lock and unlock genes that prevent and trigger cancer.
How we can better ‘mine’ our genome for information
MEDIA RELEASE:
04 Nov 2010
New sequencing technologies are showing that structural change in the genome has a much greater impact on how we interpret the epigenome – the extra layer of information above the genome – than previously thought, say Garvan researchers.
What it might take to unravel the ‘lean mean machine’ that is cancer
MEDIA RELEASE:
22 Feb 2010
Garvan scientists have published a paper, online today in Nature Cell Biology, describing gene expression in a prostate cancer cell: more sweeping, more targeted and more complex than we could ever have imagined, even five years ago.
Epigenetics featured in NHMRC ‘Ten of the Best Research Projects 2009’
17 Aug 2009
The work of Garvan’s Professor Susan Clark is featured in the NHMRC (National Health and Medical Research Council) 10 of the Best Research Projects 2009 booklet, launched this morning in Canberra. Of the hundreds of research projects funded by the NHMRC each year, the booklet highlights those that best help combat some of the nation’s biggest health challenges.
A step towards finding the cancer switch
MEDIA RELEASE:
17 Jun 2009
Garvan epigeneticists describe exactly what happens to a person's DNA the moment at which a breast cancer suppressor gene is switched off - taking us one step closer towards finding ways to control the biochemical processes that 'switch on' bad genes and 'switch off' good ones.
New Australian Epigenome Alliance moves towards a Brave New World
MEDIA RELEASE:
22 Aug 2008
In the same week as the Australian Epigenome Alliance formed, Alliance member and Garvan epigenetics expert, Professor Susan Clark, was the Australian contributor to a Nature article about the global taskforce taking shape for the human epigenome project. According to Professor Clark, "we have the words, and now we need the syntax or grammar to make sense of them."
Garvan cancer researcher wins Premier's Award
18 Jun 2008
Garvan researcher Rebecca Hinshelwood received the highly coveted $10,000 Premier’s Award for Outstanding Cancer Research Scholar at a gala ceremony last month. The award, from the Cancer Institute of NSW, is a form of educational scholarship.
Cancer genetics to combine forces with nanotechnology to fight breast cancer
MEDIA RELEASE:
04 Oct 2007
Associate Professor Susan Clark, head of Garvan’s Epigenetics Research Group, will play a leading role in a $5 million national research program called "Nanoscaled epigenetic biosensors: How combining two novel technologies will help Advanced Breast Cancer" announced today by the National Breast Cancer Foundation.
Cancer cells suppress large regions of DNA by a reversible process that can be tackled with new therapies
05 Apr 2006
Cancer researchers at Sydney’s Garvan Institute, in collaboration with Spanish scientists, have formulated a new concept for how cancer cells can escape normal growth controls, which may have far-reaching implications for the new generation of cancer therapies.
PM opens ACRF Unit for Molecular Genetics of Cancer at Garvan on May 16 2005
16 May 2005
Prime Minister opens ACRF Unit for Molecular Genetics of Cancer at Garvan
