Dr Cecile King
Senior Research Fellow; Group leader, Immunology Program, Garvan Institute of Medical Research
Email: c.king 'at' garvan.org.au
Research Group: Mucosal Autoimmunity
Cecile set up the Mucosal Autoimmunity Group at Garvan in early 2005. Prior to that, she had been researching type 1 diabetes at the Scripps Research Institute in California.
Cecile’s group is looking at the role of a cytokine (or protein) called interleukin 21 (IL 21) and its role in a variety of autoimmune diseases, including type 1 diabetes.
Education
PhD Institute for Child Health Research, University of Western Australia
BSc University of Western Australia
Publilcations
King C, Ilic A, Koelsch K, Sarvetnick N. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 2004; 117:265-277.
King C, Mueller R, Malo Cleary M, Krishner M, Ahmed R, King E, Sarvetnick N. Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T cell responses. Nature Medicine 2001; 7:206-214.
King C, Davies J, Mueller R, Lee M-S, Krahl T, Yeung B, O'Connor E, Sarvetnick N. TGF-β1 alters APC preference, polarizing islet antigen responses to Th2. Immunity 1998; 8:601-613.
King C, Brennan S, Thompson PJ, Stewart GA. Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium. Journal of Immunology 1998; 3645-3651
King C, Sarvetnick N. Organ-specific autoimmunity (Review). Current Opinion in Immunology 1997; 9(6):863-71
Search for all publications by Cecile King
Areas of Interest
Autoimmunity, type 1 diabetes, mucosal immunity, tolerance
News
The genetic fuse that may ignite Type 1 diabetes
MEDIA RELEASE:
20 Oct 2009
Garvan scientists have discovered that a tiny genetic irregularity, which boosts the expression of a key gene, may lead to the development of Type 1 diabetes. While there is no cure yet, prevention therapies are on the horizon, making the development of reliable screening tools critical. And that's where the current finding has promise.
Garvan immunology students win main prizes at ASI conference
19 Dec 2008
For the second year in a row, a PhD student from Garvan has won the very prestigious New Investigator Award at the annual Australasian Society for Immunology (ASI) conference, held last week in Canberra. The 2008 winner is Alexis Vogelzang.
Immunology in the very blood of Castle Harlan award winner
31 Oct 2008
Helen McGuire has received the $10,000 USD Castle Harlan award for being the most outstanding early career PhD student at the Garvan Institute in 2008. Castle Harlan is a distinguished and philanthropic US-based private equity firm that wishes to support the kind of medical research being undertaken at Garvan.
