Professor Jonathan Sprent FAA FRS
Senior Principal Research Fellow; Group leader, Immunology, and Inflammation Research Program, Garvan Institute of Medical Research
Email: j.sprent 'at' garvan.org.au
Research Group: Cellular Immunity
MBBS Medical School, University of Queensland, Brisbane
BSc (Pathology) University of Queensland, Brisbane
PhD (Immunology) Walter and Eliza Hall Institute, Melbourne
Awards and Honours
Fellow of the Royal Society
Fellow of the Australian Academy
Honorary member, British Society of Immunology
J.Allyn Taylor International Prize in Medicine
1998 President of the American Association of Immunologists
Boyman O, Purton JF, Surh CD, Sprent J. Cytokines and T-cell homeostasis. Curr Opin Immunol 2007. in press.
Purton JF, Tan JT, Rubinstein MP, Kim DM, Sprent J, Surh CD. Antiviral CD4+ memory T cells are IL-15 dependent. J Exp Med 2007; 204(4):951-61.
Boyman O, Kovar M, Rubinstein MP, Surh CD, Sprent J. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 2006; 311(5769):1924-7.
Ishimaru N, Kishimoto H, Hayashi Y, Sprent J. Regulation of naive T cell function by the NF-kappaB2 pathway. Nat Immunol 2006; 7(7):763-72.
Surh CD, Sprent J. On the TRAIL of homeostatic memory T cells. Nat Immunol 2006; 7(5):439-41.
Rubinstein MP, Kovar M, Purton JF, Cho JH, Boyman O, Surh CD, Sprent J. Converting IL-15 to a superagonist by binding to soluble IL-15Ralpha. Proc Natl Acad Sci U S A 2006; 103(24):9166-71.
McKay D, Shigeoka A, Rubinstein M, Surh C, Sprent J. Simultaneous deletion of MyD88 and Trif delays major histocompatibility and minor antigen mismatch allograft rejection. Eur J Immunol 2006; 36(8):1994-2002.
Kovar M, Boyman O, Shen X, Hwang I, Kohler R, Sprent J. Direct stimulation of T cells by membrane vesicles from antigen-presenting cells. Proc Natl Acad Sci U S A 2006; 103(31):11671-6.
Boyman O, Cho JH, Tan JT, Surh CD, Sprent J. A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells. J Exp Med 2006; 203(7):1817-25.