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Professor Jonathan Sprent FAA FRS

 

Senior Principal Research Fellow; Group leader, Immunology, and Inflammation Research Program, Garvan Institute of Medical Research

Email: j.sprent 'at' garvan.org.au
Research Group: Cellular Immunity

 
 

Education

MBBS Medical School, University of Queensland, Brisbane
BSc (Pathology) University of Queensland, Brisbane
PhD (Immunology) Walter and Eliza Hall Institute, Melbourne

Awards and Honours

Fellow of the Royal Society
Fellow of the Australian Academy
Honorary member, British Society of Immunology
J.Allyn Taylor International Prize in Medicine
1998 President of the American Association of Immunologists

Publications

Boyman O, Purton JF, Surh CD, Sprent J. Cytokines and T-cell homeostasis. Curr Opin Immunol 2007. in press.

Purton JF, Tan JT, Rubinstein MP, Kim DM, Sprent J, Surh CD. Antiviral CD4+ memory T cells are IL-15 dependent. J Exp Med 2007; 204(4):951-61.

Boyman O, Kovar M, Rubinstein MP, Surh CD, Sprent J. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 2006; 311(5769):1924-7.

Ishimaru N, Kishimoto H, Hayashi Y, Sprent J. Regulation of naive T cell function by the NF-kappaB2 pathway. Nat Immunol 2006; 7(7):763-72.

Surh CD, Sprent J. On the TRAIL of homeostatic memory T cells. Nat Immunol 2006; 7(5):439-41.

Rubinstein MP, Kovar M, Purton JF, Cho JH, Boyman O, Surh CD, Sprent J. Converting IL-15 to a superagonist by binding to soluble IL-15Ralpha. Proc Natl Acad Sci U S A 2006; 103(24):9166-71.

McKay D, Shigeoka A, Rubinstein M, Surh C, Sprent J. Simultaneous deletion of MyD88 and Trif delays major histocompatibility and minor antigen mismatch allograft rejection. Eur J Immunol 2006; 36(8):1994-2002.

Kovar M, Boyman O, Shen X, Hwang I, Kohler R, Sprent J. Direct stimulation of T cells by membrane vesicles from antigen-presenting cells. Proc Natl Acad Sci U S A 2006; 103(31):11671-6.

Boyman O, Cho JH, Tan JT, Surh CD, Sprent J. A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells. J Exp Med 2006; 203(7):1817-25.

Search for all publications by J Sprent

 
 
 

News

 

Scripps cancer findings good news for Garvan immunologist

22 Oct 2008
While a member of the research faculty at California's Scripps Research Institute, Garvan's Professor Jonathan Sprent collaborated with Professor Charles Surh to develop a novel complex designed to rev up the immune system to fight cancer. Scripps researchers, including Surh, have now tested the complex in mice for cancer treatment and found it to be effective.
 
 

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