How DreamLab Supports Our Researchers

People lying in bed

A complex genetic network known as the genome, a DNA code made up of 3 billion “letters”, controls the function of every cell in your body. To maintain normal function cells must make a faithful copy of this genome every time they divide. However, mistakes are made in the copying process (we call them mutations). These mistakes/mutations can disrupt the complex genetic network, disrupting controls on cell growth and forming a tumour.

The more we learn about cancer at the genetic level, the more we understand that each person’s disease is unique. In fact, this genetic complexity is one of the most challenging aspects of understanding cancer and developing therapies.

Over 100 different types of cancer have been described using anatomical classifications – that is, by the organ or cell type in which they originate (such as prostate cancer, bowel cancer, breast cancer, skin cancer and lung cancer). Recent advancements in DNA sequencing have made it possible to rapidly and affordably sequence the genomes of thousands of cancer patients. Based on this amazing insight, genetic “signatures” are emerging as a much more powerful way to determine appropriate treatment.

The Problem

Huge advances in DNA sequencing technology have enabled rapid and affordable sequencing of cancer genomes, creating a virtual tsunami of genetic information. One way of processing this information is to run computer-based simulations to model the genetic networks in cancer and find common “signatures” among different patients. These signatures will help us understand how different patients respond differently to various drugs, help us predict which patients will benefit, and help us find completely new strategies for treating cancer.

However, we are limited by the huge computing power required to run this simulation process.

The Solution

  • Use the processing power of smartphones while you sleep
  • The tiny but powerful brain in your smartphone could help us find the next breakthrough in cancer.
  • Smartphones just got smarter
  • Efficient, powerful

The Dreamlab app can help researchers find a new way to select the best drug for individual cancer patient.

We developed a novel computational method to solve this problem, which could be used to subtype cancer patients and help find the optimal therapy.

DreamLab provides a unique opportunity for us to finish the analysis using millions of smartphones. The whole analysis will be split into millions of tiny tasks, which will be distributed to your smartphone and processed while you sleep.

Impact

By supporting the Vodafone Foundation DreamLab initiative, your data will help Garvan Researchers find a new way to select the best drug for individual cancer patient.

By supporting the Vodafone Foundation DreamLab initiative, your data will help Garvan Researchers advance our understanding of complex mechanisms underlying cancer, which will help develop new therapy in the future.