Osteoporosis causes bones to become fragile and weak increasing the
risk of fracture. Half of all women over 60 in Australia will suffer an
osteoporotic fracture in their lifetime. Fractures can be painful and
restrict activity. At the Garvan Institute of Medical Research, we
conduct research into osteoporosis and its treatment.
We are looking for female volunteers who:
are 60 - 90 years old
have had a vertebral (spinal) fracture due to osteoporosis
are interested in being part of a clinical trial that compares a new osteoporosis treatment to current medications. Both are designed to stop further fractures.
Healthy male volunteers needed for diabetes research.
We are looking for healthy male volunteers who have close relatives with Type 2 Diabetes for a study investigating the role of autonomic nervous system activity in the development of the disease.
The study involves visiting the Garvan Institute in Darlinghurst for one morning during working hours. You will be asked to provide a blood sample, have your heart rate measured using an ECG machine, and have your body composition measured using a low-dose X-ray scan. You will be reimbursed for expenses.
If you are willing and are aged 50-65 years and healthy, please contact
Lynne Schofield 9295 8231 or Dr Dorit Samocha Bonet 9295 8309
Overweight volunteers (ie body mass index > 30) are needed to participate in a study screening for a gene which links to obesity.
During a preliminary visit, a blood test and various body measurements will be taken to assess your suitability for the study. If you match our criteria, we would invite you back for a full metabolic assessment.
Why are we doing this study?
The gene in question (MC4R) is present in up to 6% of overweight people - and is associated with greater appetite, predisposing people to obesity from childhood. The gene is also associated with lower blood pressure than might be expected .
There are different kinds of obesity - with some people remaining metabolically healthy, while others become susceptible to high cholesterol, high blood pressure and Type 2 diabetes. We are interested in finding out as much as possible about why such differences occur.
Our research might help future screening of obese people to identify those who are predisposed to illness, and those who are not.
Anticipated recruitment is April 2011 to June 2013
Enquiries: Dr Daniel Chen (02) 9295 8557 or firstname.lastname@example.org Research Nurse Renee Richens on (02) 9295 8215 Or email email@example.com
We are looking for healthy volunteers: men and postmenopausal women, aged 50 - 70 years for research into hormones and body fat.
This study involves visits over a 14 week period to the Garvan to study the effects of three commonly used medications, oestrogen (women only), letrozole and tamoxifen on the burning of fat in the body.
We will investigate how fat is utilised at whole body and liver level.
For further information, please contact Dr Vita Birzniece (02) 9295 8483, firstname.lastname@example.org
or Vanessa Travers (02) 9295 8232, email@example.com
The Type 1 Diabetes Prevention Trial, also known as the Intranasal Insulin Trial (INIT II), is part of a coordinated global effort to develop a vaccine for type 1 diabetes. The trial, which began in 2006, is jointly funded by the National Health and Medical Research Council (NHMRC) and the Juvenile Diabetes Research Foundation (JDRF), through the Diabetes Vaccine Development Centre (DVDC).
The trial is designed to determine if the onset of type 1 diabetes can be delayed or prevented by a nasal insulin vaccine. Therefore, if the trial was successful it would benefit people at risk for type 1 diabetes by forestalling or preventing the development of type 1 diabetes in them.
The trial has a strict inclusion and exclusion criteria that participants need to meet in order to participate. Anyone aged between 4-30 years who has a first-degree (mother, father, brother, sister, son, daughter) or second-degree (aunt, uncle, grandmother, grandfather, half-brother, half-sister) relative with type 1 diabetes can participate. If the relative with type 1 diabetes is your grandmother, grandfather, aunt, uncle, niece, nephew, half-sister or half-brother, i.e. a second degree relative, you need to be aged 4-20 years to participate. The first step is to have a free blood test for antibodies that indicate the risk of getting type 1 diabetes.