Nuffield Department of Surgical Sciences and Nuffield Department of Orthopaedics, Rheumatology and Surgical Sciences

Oxford, UK

The Bone Oncology Research Group is jointly appointed between Nuffield Department of Surgical Sciences (NDS) & Nuffield Department of Orthopaedics Rheumatology and Surgical Sciences (NDORMS), and is located within the Botnar Research Centre, University of Oxford Institute of Musculoskeletal Research Sciences.Nuffield dep

The Botnar Research Centre is on the grounds of the Nuffield Orthopaedic Centre, enabling basic researchers to work alongside clinicians to facilitate the translation of basic research from bench to bedside.

The Bone Oncology Group is headed by Dr Claire Edwards and incorporates cell and molecular approaches, murine models of cancer-induced bone disease and translational research utilising clinical samples. Research is focused predominantly on multiple myeloma and prostate cancer bone metastases. Within NDS are many clinical cancer specialties, including urology, providing excellent interactions with urologists, and facilitating acquisition of clinical samples.

Prof Freddie Hamdy is the Chief Investigator of many studies, including the ProtecT (Prostate testing for cancer and Treatment) and the ProMPT study (Prostate Mechanisms of Progression and Treatment), providing and invaluable source of sequential samples from men with prostate cancer.