Clinical Genomics

Clinical Genomics

Image of Aga Borcz, Senior Research Assistant, in the Sequencing room of the Kinghorn Centre for Clinical Genomics Photo credit: P. Morris/Garvan

Overview

The Kinghorn Centre for Clinical Genomics (KCCG) was established by the Garvan Institute in 2012 to advance the use of genomic information in patient care. Clinical genomics is a rapidly evolving field focused on the use of genomic sequencing information in patient diagnosis and treatment. KCCG employs world-leading DNA analysis technology and expertise in genetics, pathology and bioinformatics to deliver and interpret genome sequences for research and clinical use. Find out more about our mission and vision in About KCCG.

Technology and Partnerships

In 2014, Garvan acquired a HiSeq X Ten sequencing platform, which provides KCCG with powerful genome sequencing potential and the capability to sequence up to 18,000 whole human genomes per year.

In 2014, the Centre also became a genomics node of BioPlatforms Australia. To streamline access to whole human genome sequencing for Australian researchers, Garvan has partnered with Bioplatforms facilities AGRF (Australian Genome Research Facility) and the Ramaciotti Centre for Genomics.

Research Scope

Research at the KCCG is focused on improving the value and interpretation of genomes for patient care.  The Centre will continue to facilitate genome-based research, initially in cancer and monogenic diseases, but also in complex disease such as diabetes, osteoporosis and immunological disease.

Clinical Application

KCCG will act as a mechanism to translate genomic research into the clinic, and is seeking accreditation to enable it to provide state-of-the-art interpretation of genomic data directly to clinicians.  We are currently undergoing accreditation and anticipate being able to offer clinical services in the second quarter of 2016. For Garvan's perspective on how this may proceed, see The impact of genomics on the future of medicine and health in the Centenary Issue of the Medical Journal of Australia.

Public and professional engagement will be vital to realising the potential of clinical genomics in Australia, and the Centre is developing programs, resources and opportunities for health practitioners and communities to learn about genomics.

In the News

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