Dr Dessislava Mladenova

Research Officer

I was born in one of the oldest cities in Europe, Sofia in Bulgaria, where I obtained my bachelor’s degree in Molecular Biology. I moved to Australia and started my doctoral training at the Garvan Institute of Medical Research in 2006, working on the chemoprevention of colorectal cancer. 

I fell in love with the vibe in the Institute and I decided to continue working here as a postdoctoral research officer. I have recently moved to the field of neuroscience and bioinformatics, learning the computational tools required to study the mechanisms of ageing in the brain and processes contributing to neurodegeneration. On a broader scale, bioinformatics tools enable me to research the origins and evolution of human cognition.

Research Interests

Genomics/Transcriptomics
Molecular evolution of the primate brain
How ageing is programmed
Neurodegenerative disorders
The origins of human cognition

Awards and Honours

2012 - Sydney Cancer Conference Early career Best oral presentation award
2011 - Australian Society for Medical Research award for best postdoctoral poster, ASMR meeting, Sydney
2008-2009 - Australian Government Commercialisation Training Scheme Scholarship
2007-2010 - Cancer Institute NSW Research Scholar Award
2006-2010 - Australian Postgraduate Award
2000-2004 - University of Sofia scholarship for academic excellence

Education

2011 - PhD, University of New South Wales - Australia
2009 - Graduate Certificate in Research Management and Commercialisation, University of New South Wales - Australia
2005 - BSc Molecular Biology, University of Sofia - Bulgaria

Selected Publications

Mladenova D., Pangon L., Currey N., Ng I., Musgrove E., Grey S., Kohonen-Corish M. Sulindac activates NFkB signaling in colon cancer cells, Cell Communication and Signalling. 2013; 11:73

Mladenova D. and Kohonen-Corish M. Mouse models of Inflammatory Bowel Disease - Insights into the mechanisms of inflammation-associated colorectal cancer. Review article In Vivo. 2012; 26:627-646

Mladenova, D., Daniel, J. J., Dahlstrom, J. E., Bean, E., Gupta, R., Pickford, R., Currey, N., Musgrove, E. A., and Kohonen-Corish, M. R. The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon. Gut. 2011; 60:350-360.

Selinger, C. I., Cooper, W. A., Al-Sohaily, S., Mladenova, D. N., Pangon, L., Kennedy, C. W., McGaughan, B. C., Stirzaker, C., and Kohonen-Corish, M. R. Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. J Thorac Oncol. 2011; 6:1179-1189

Pangon L, Sigglekow ND, Larance M, Al-Sohaily S, Mladenova D, Selinger C, Musgrove EA, Kohonen-Corish MRJ. 'Mutated in colorectal cancer' (MCC) is a novel target of the UV-induced DNA damage response. Genes & Cancer. 2010; 1 (9): 917-926.

Dr Dessislava Mladenova



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