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TNF and leptin tell essentially the same story in Alzheimer's disease

Abstract

Both tumor necrosis factor (TNF) and leptin are, independently, under investigation as the central mechanism for Alzheimer's disease. The wider literature provides every indication that both mediators are part of the same pathways thought to cause functional loss in this condition. This association, which has not been specifically addressed in the Alzheimer's disease literature, may be a useful link to expedite future study into the pathogenesis of this condition.

Type Journal
ISBN 1875-8908 (Electronic) 1387-2877 (Linking)
Authors Clark, I. A.; Alleva, L. M.; Vissel, B.;
Garvan Authors Dr Bryce Vissel
Publisher Name J ALZHEIMERS DIS
Published Date 2011-01-01 00:00:00
Published Volume 26
Published Issue 2
Published Pages 201-5
URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21593567
Status Published In-print
OpenAccess Link https://publications.gimr.garvan.org.au/download.php?11162_11595/proof Clark 110920.pdf