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Locating the scala media in the fixed human temporal bone for therapeutic access: a preliminary study

Abstract

OBJECTIVE: To investigate the location of the scala media in relation to the round window niche in human temporal bones. DESIGN: Ten human temporal bones were investigated by radical mastoidectomy and promontory drill-out. SETTING: Temporal bone laboratory.Outcome measures: The distance from the scala media to the anterior edge of the round window niche, measured by Fisch's stapedectomy measuring cylinders. RESULTS: The scala media was identified at the transection point of a vertical line 1.6 to 2.2 mm (mean=1.8 mm; standard deviation=0.2) anterior to the anterior edge of the round window niche and a horizontal line 0.2 mm inferior to the lower border of the oval window. CONCLUSION: This report demonstrates the point of entry into the scala media via the promontory in fixed temporal bone models, which may provide a site of entry for stem cells and gene therapy insertion.

Type Journal
ISBN 1748-5460 (Electronic)
Authors Pau, H.;Fagan, P.;Oleskevich, S. :
Publisher Name J LARYNGOL OTOL
Published Date 2006-01-01 00:00:00
Published Volume 120
Published Issue 11
Published Pages 914-5
URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16882361
Status Published In-print