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Antiretroviral therapy and the human immunodeficiency virus--improved survival but at what cost?

Abstract

Patients infected with human immunodeficiency virus are living longer since the introduction of combination antiretroviral therapy more than a decade ago - but at what cost? Highly active antiretroviral therapy has been associated with lipodystrophy and associated metabolic derangements such as dyslipidaemia, insulin resistance and diabetes. These complications are likely to contribute to an increased risk of premature and accelerated atherosclerosis with growing concern about potential cardiovascular consequences.

Type Journal
ISBN 1463-1326 (Electronic)
Authors Bradbury, R. A.;Samaras, K. :
Garvan Authors Prof Katherine Samaras
Publisher Name DIABETES OBES METAB
Published Date 2008-01-01 00:00:00
Published Volume 10
Published Issue 6
Published Pages 441-50
URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17825081
Status Published In-print
OpenAccess Link https://publications.gimr.garvan.org.au/download.php?2321_10135/08 Bradbury DOM 10.pdf