The role of receptor subtype diversity in the CNS
The molecular characterization of neuroreceptors and voltage-gated ion channels has revealed that receptor subtype heterogeneity is a common feature of chemical and electrical signal reception. The use of distinct genes encoding receptor subtypes is a favoured mechanism for generation of this diversity. We propose that the significance of the multiplicity and diversity of signal reception proteins is to increase the information-handling capacity of neurons. This may contribute to neural plasticity.
|Authors||Schofield, P. R.;Shivers, B. D.;Seeburg, P. H. :|
|Publisher Name||TRENDS NEUROSCI|
|Published Date||1990-01-01 00:00:00|