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Role of growth hormone in fluid homeostasis

Abstract

Administration of human growth hormone (GH) is associated with clinically significant sodium retention. There is evidence that the antinatriuretic properties of GH are mediated by activation of the renin-angiotensin system, as well as a direct action on the kidney. The antinatriuretic properties of GH may be of pathophysiological significance in acromegaly, where increased body sodium and plasma volume occur, and may contribute to the development of hypertension in this condition.

Type Journal
ISBN 0301-0163 (Print)
Authors Ho, K. Y.;Kelly, J. J. :
Publisher Name HORM RES PAEDIATR
Published Date 1991-01-01 00:00:00
Published Volume 36 Suppl 1
Published Pages 44-8
URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1806484
Status Published In-print