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G protein-coupled receptors

Abstract

The diversity of the G protein-coupled receptor superfamily is now being realised with the molecular cloning of DNA encoding many new receptors and receptor subfamilies. The existing pharmacological definitions of receptor subtypes have been extended dramatically with identification of additional subtypes at the molecular level. Functional analysis of cloned receptors by expression in heterologous cell types has demonstrated that individual receptor subtypes can couple to a variety of different effector systems.

Type Journal
ISBN 0955-0674 (Print)
Authors Iismaa, T. P.;Shine, J. :
Garvan Authors Prof John Shine
Publisher Name CURR OPIN CELL BIOL
Published Date 1992-01-01 00:00:00
Published Volume 4
Published Issue 2
Published Pages 195-202
URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1318058
Status Published In-print