Antibody Engineering
Our laboratory is working on the development of novel antibody therapeutics. In particular, we are interested in the engineering of human antibody fragments, which are considerably smaller than current monoclonal antibodies and in the mechanisms of immunomodulation by intravenous immunoglobulin. Human antibody fragments (such as domain antibodies) can be generated by genetic engineering technology, completely bypassing the use of animals. These fragments can be produced in large quantities in bacteria and open up promising new routes for administration and imaging. They also represent robust building blocks for the generation of antibody therapeutics therapeutic. We are applying our technology to targets in cancer and inflammatory diseases.
Career opportunities
We are always looking for talented, ambitious students and postdocs to
join our group. Please contact Daniel for further information.
Staff
 Research AssistantPeter Schofield |
 Research AssistantStephen McKay |
 PhD StudentRomain Rouet |
 PhD StudentKip Dudgeon |
 PhD Student
Brendan Roome |
 PhD StudentRodrigo Vazquez-lombardi |
| Visiting Student Iris Kokmejer Student Joseph Swift |
 Research AssistantJessica Stolp |
| Honorary Researcher Dr Mark Rocco |
|
| Emeritius Professor Antony Basten AO FAA FTSE
also holds an appointment in the antibody engineering and
therapeutics group See Professor Basten's Profile |
