Chisholm
A key research goal is to identify the molecular mechanisms by which visceral fat (fat tissue near the abdominal organs) generates insulin resistance. Visceral fat cells are different to other fat cells; they are more metabolically active, indiscriminately ‘spit out’ fatty acids which contributes to insulin resistance in liver and muscle, and they also produce hormones which may modify the action of insulin. The group are also interested in studying the changes that take place in the liver of patients infected with Hepatitis C and also why the muscles of these patients becomes insulin resistant.
Staff
Clinical Research NurseLynne Schofield |
Research OfficerDr Kerry-Lee Milner |
See also:
News
Surprising findings about Hepatitis C and insulin resistance
MEDIA RELEASE:
09 Mar 2010
Researchers at Garvan have now confirmed the link between Hepatitis C and Type 2 diabetes - people with the virus being 3 to 4 times more likely to develop diabetes, owing to high levels of insulin resistance in muscle. There is practically no insulin resistance in the liver, however, a surprising finding given that Hepatitis C is a liver disease.
New Fellowship Strengthens Garvan Potential to find a cure for Type 2 diabetes
MEDIA RELEASE:
06 Dec 2007
We are very pleased to announce the establishment of the GlaxoSmithKline Don Chisholm Fellowship for Diabetes Research – a position dedicated to vital research into the causes, processes and treatments for Type 2 diabetes, one of Australia’s most common and serious diseases.
Marcia Shines For Garvan
21 Sep 2007
At the 2007 Garvan Chairman’s Dinner held on 18 September, Marcia Hines thrilled our guests with exquisite renditions of some of her greatest hits in honour of Professor Don Chisholm – a leader in diabetes research and care for over 40 years….


Clinical Research Nurse
Research Officer