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Garvan Institute

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Cooper

 

Group Leader
Dr Antony Cooper

 

We want to understand how cells cope, or fail to cope, with the stress that can result from the over-production of proteins and misfolding of proteins within a cellular compartment called the endoplasmic reticulum (ER). ER stress is directly applicable to a growing number of diseases including diabetes, motor neuron disease and Parkinson’s disease. Either the cell ‘burns out’, generates an excess of harmful products, or accumulates unmanageable amounts of unusable proteins, which ultimately lead to cell death. If we can elucidate how these stressors induce cell death, we may be able to identify potential points of intervention to help the cells deal with the extra demands.

Staff

Kathryn HillSenior Research Officer
Dr Kathryn Hill
c_lang90.jpgPhD Student
Charmaine Lang
Stephanie KongPhD Student
Stephanie Kong
Lee MarshallPhD Student
Lee Marshall
Louise CottleResearch Assistant
Louise Cottle
Harry WangHonours Student
Harry Wang
Visiting Student
Karen Murphy


 

 

News

 

How yeast is helping us to understand Parkinson's disease

MEDIA RELEASE: 27 Feb 2009
Teams of scientists from Australia and the United States have used yeast and mammalian cells to discover a connection between genetic and environmental causes of Parkinson’s disease. The findings were published online this month in Nature Genetics.
 
 

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