Mammary Development
Development of the mammary gland occurs in defined stages that are governed by the hormones that regulate reproductive events. Our hypothesis is that the genes that control normal mammary development can become mutated or dysregulated in breast cancer, altering or subverting their normal function and so contributing to the disease process. We must understand how genes program normal development if we are to understand how the program goes awry in cancer. Key genes in these processes may provide targets for future therapies. Our current focus is on discovering the genes that respond to prolactin - a hormone that plays an important role in normal mammary cell proliferation, differentiation and lactation, but when in excess can increase the risk of developing breast cancer.
Staff
 Research OfficerDr Heather Lee |
 Research OfficerDr David Gallego-Ortega |
 Research BioinformaticianDr Daniel Roden |
 Research OfficerDr Catherine Piggin |
 Research AssistantStephanie Allerdice |
 Research AssistantAnita Ledger |
 Visiting ScientistDr Matt Naylor |
 Senior Research OfficerDr Samantha Oakes |
 PhD StudentAnne-Marie Mooney |
 PhD StudentAlison Ferguson |
