James
One of the major actions of insulin that becomes defective in type 2 diabetes is the regulated entry of nutrients into our muscle and fat cells. Our goal is to use our newly-developed molecular imaging methods to uncover the path that insulin takes from when it binds to muscle and fat cells to when it encounters its final target, and how it achieves its ultimate goal: allowing glucose to gain entry to a cell. Numerous proteins interact with insulin and glucose on this journey. We are also intrigued by the constant movement of proteins within cells, the direction and rate of which is precisely controlled and are investigating the mechanism for the regulation of protein trafficking.
Staff
 Research OfficerDr Jacqueline Stoeckli |
|
 Research OfficerDr Kyle Hoehn |
|
 Research OfficerDr Ping Zhao |
PhD Student Matt Prior |
| PhD Student Mark Larance |
 PhD StudentPoh Sim Khoo |
| PhD Student Jamie Lopez |
|
 PhD StudentSamantha Hocking |
PhD Student Jonathan Davey |
 PhD StudentAlex Rowland |
 PhD
StudentYvonne Ng |
 PhD StudentLindsay Wu |
News
Will bitter melon in a bottle live up to its promise?
MEDIA RELEASE:
21 Jan 2009
Diabetes researchers at Garvan have received nearly $300,000 in Commonwealth funding to advance their research into the therapeutic properties of bitter melon, a vegetable and traditional Chinese medicine.
Completely novel action of insulin unveiled
MEDIA RELEASE:
05 Nov 2008
Freddy Yip, a Garvan PhD student, has found a significant missing link in our knowledge about insulin and how it helps cells absorb glucose. Freddy's finding reveals an important molecular mechanism activated by insulin.
Research agreement to reveal secret lives of cells
MEDIA RELEASE:
06 Aug 2008
Garvan and CSIRO have signed a three-year collaboration agreement to investigate important cellular processes, including those impaired by diseases such as diabetes. They will be using a new computer vision system they developed jointly to watch intricate cellular processes in real time.
