5109 items matching your search terms.
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Treatment of type 2 diabetes with the designer cytokine IC7Fc
- Findeisen, M.; Allen, T. L.; Henstridge, D. C.; Kammoun, H.; Brandon, A. E.; Baggio, L. L.; Watt, K. I.; Pal, M.; Cron, L.; Estevez, E.; Yang, C.; Kowalski, G. M.; O'Reilly, L.; Egan, C.; Sun, E.; Thai, L. M.; Krippner, G.; Adams, T. E.; Lee, R. S.; Grotzinger, J.; Garbers, C.; Risis, S.; Kraakman, M. J.; Mellet, N. A.; Sligar, J.; Kimber, E. T.; Young, R. L.; Cowley, M. A.; Bruce, C. R.; Meikle, P. J.; Baldock, P. A.; Gregorevic, P.; Biden, T. J.; Cooney, G. J.; Keating, D. J.; Drucker, D. J.; Rose-John, S.; Febbraio, M. A.
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NATURE
574
(7776)
:63-68,
2019
10.1038/s41586-019-1601-9
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The role of inflammation and endoplasmic reticulum stress in obesity-related cognitive impairment
- Liu, Y.; Yu, J.; Shi, Y. C.; Zhang, Y.; Lin, S.
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LIFE SCIENCES
233
:116707,
2019
10.1016/j.lfs.2019.116707
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Accurate detection of m(6)A RNA modifications in native RNA sequences
- Liu, H.; Begik, O.; Lucas, M. C.; Ramirez, J. M.; Mason, C. E.; Wiener, D.; Schwartz, S.; Mattick, J. S.; Smith, M. A.; Novoa, E. M.
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Nature Communications
10
(1)
:4079,
2019
10.1038/s41467-019-11713-9
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Phlda3 regulates beta cell survival during stress
- Bensellam, M.; Chan, J. Y.; Lee, K.; Joglekar, M. V.; Hardikar, A. A.; Loudovaris, T.; Thomas, H. E.; Jonas, J. C.; Laybutt, D. R.
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Scientific Reports
9
(1)
:12827,
2019
10.1038/s41598-019-49289-5
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CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
- Vennin, C.; Melenec, P.; Rouet, R.; Nobis, M.; Cazet, A. S.; Murphy, K. J.; Herrmann, D.; Reed, D. A.; Lucas, M. C.; Warren, S. C.; Elgundi, Z.; Pinese, M.; Kalna, G.; Roden, D.; Samuel, M.; Zaratzian, A.; Grey, S. T.; Da Silva, A.; Leung, W.; Mathivanan, S.; Wang, Y.; Braithwaite, A. W.; Christ, D.; Benda, A.; Parkin, A.; Phillips, P. A.; Whitelock, J. M.; Gill, A. J.; Sansom, O. J.; Croucher, D. R.; Parker, B. L.; Pajic, M.; Morton, J. P.; Cox, T. R.; Timpson, P.
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Nature Communications
10
(1)
:3637,
2019
10.1038/s41467-019-10968-6
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Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes-cardiovascular and renal benefits in patients with chronic kidney disease
- Milder, T. Y.; Stocker, S. L.; Samocha-Bonet, D.; Day, R. O.; Greenfield, J. R.
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EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
2019
10.1007/s00228-019-02732-y
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Use of synthetic DNA spike-in controls (sequins) for human genome sequencing
- Blackburn, J.; Wong, T.; Madala, B. S.; Barker, C.; Hardwick, S. A.; Reis, A. L. M.; Deveson, I. W.; Mercer, T. R.
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Nature Protocols
14
(7)
:2119-2151,
2019
10.1038/s41596-019-0175-1
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Multilayered control of exon acquisition permits the emergence of novel forms of regulatory control
- Avgan, N.; Wang, J. I.; Fernandez-Chamorro, J.; Weatheritt, R. J.
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GENOME BIOLOGY
20
(1)
:141,
2019
10.1186/s13059-019-1757-5
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The FOXP3Delta2 isoform supports Treg cell development and protects against severe IPEX syndrome
- Frith, K.; Joly, A. L.; Ma, C. S.; Tangye, S. G.; Lohse, Z.; Seitz, C.; Verge, C. F.; Andersson, J.; Gray, P.
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
144
:317-320,
2019
10.1016/j.jaci.2019.03.003
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Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes
- Bradford, S. T.; Nair, S. S.; Statham, A. L.; van Dijk, S. J.; Peters, T. J.; Anwar, F.; French, H. J.; von Martels, J. Z. H.; Sutcliffe, B.; Maddugoda, M. P.; Peranec, M.; Varinli, H.; Arnoldy, R.; Buckley, M.; Ross, J. P.; Zotenko, E.; Song, J. Z.; Stirzaker, C.; Bauer, D. C.; Qu, W.; Swarbrick, M. M.; Lutgers, H. L.; Lord, R. V.; Samaras, K.; Molloy, P. L.; Clark, S. J.
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Scientific Reports
9
(1)
:9511,
2019
10.1038/s41598-019-45777-w
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Gallium-68-prostate-specific membrane antigen ((68) Ga-PSMA) positron emission tomography (PET)/computed tomography (CT) predicts complete biochemical response from radical prostatectomy and lymph node dissection in intermediate- and high-risk prostate cancer
- van Leeuwen, P. J.; Donswijk, M.; Nandurkar, R.; Stricker, P.; Ho, B.; Heijmink, S.; Wit, E. M. K.; Tillier, C.; van Muilenkom, E.; Nguyen, Q.; van der Poel, H. G.; Emmett, L.
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BJU International
124
(1)
:62-68,
2019
10.1111/bju.14506
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Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4(+) T cells
- Bier, J.; Rao, G.; Payne, K.; Brigden, H.; French, E.; Pelham, S. J.; Lau, A.; Lenthall, H.; Edwards, E. S. J.; Smart, J. M.; Cole, T. S.; Choo, S.; Joshi, A. Y.; Abraham, R. S.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; Holland, S. M.; Notarangelo, L. D.; Uzel, G.; Ma, C. S.; Brink, R.; Tangye, S. G.; Deenick, E. K.
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
144
(1)
:236-253,
2019
10.1016/j.jaci.2019.01.033
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African KhoeSan ancestry linked to high-risk prostate cancer
- Petersen, D. C.; Jaratlerdsiri, W.; van Wyk, A.; Chan, E. K. F.; Fernandez, P.; Lyons, R. J.; Mutambirw, S. B. A.; van der Merwe, A.; Venter, P. A.; Bates, W.; Bornman, M. S. R.; Hayes, V. M.
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BMC Medical Genomics
12
(1)
:82,
2019
10.1186/s12920-019-0537-0
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Estrogen receptor signaling is reprogrammed during breast tumorigenesis
- Chi, D.; Singhal, H.; Li, L.; Xiao, T.; Liu, W.; Pun, M.; Jeselsohn, R.; He, H.; Lim, E.; Vadhi, R.; Rao, P.; Long, H.; Garber, J.; Brown, M.
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
116
(23)
:11437-11443,
2019
10.1073/pnas.1819155116
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A quantitative model to predict pathogenicity of missense variants in the TP53 gene
- Fortuno, C.; Cipponi, A.; Ballinger, M. L.; Tavtigian, S. V.; Olivier, M.; Ruparel, V.; Haupt, Y.; Haupt, S.; Study, I. S. K.; Tucker, K.; Spurdle, A. B.; Thomas, D. M.; James, P. A.
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HUMAN MUTATION
40
(6)
:788-800,
2019
10.1002/humu.23739
