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Heparan sulfate proteoglycans in beta cells provide a critical link between endoplasmic reticulum stress, oxidative stress and type 2 diabetes
Dhounchak, S.; Popp, S. K.; Brown, D. J.; Laybutt, D. R.; Biden, T. J.; Bornstein, S. R.; Parish, C. R.; Simeonovic, C. J.
PLoS One 16 (6) :e0252607, 2021 10.1371/journal.pone.0252607
Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer
Baker, L. A.; Holliday, H.; Roden, D.; Krisp, C.; Wu, S. Z.; Junankar, S.; Serandour, A. A.; Mohammed, H.; Nair, R.; Sankaranarayanan, G.; Law, A. M. K.; McFarland, A.; Simpson, P. T.; Lakhani, S.; Dodson, E.; Selinger, C.; Anderson, L.; Samimi, G.; Hacker, N. F.; Lim, E.; Ormandy, C. J.; Naylor, M. J.; Simpson, K.; Nikolic, I.; O'Toole, S.; Kaplan, W.; Cowley, M. J.; Carroll, J. S.; Molloy, M.; Swarbrick, A.
BREAST CANCER RES 22 (1) :63, 2021 10.1186/s13058-020-01306-6
Intronic Haplotypes in GBA Modify Age at Diagnosis of Parkinson's: Replication in a Subgroup
O'Sullivan, J. M.; den Heijer, J. M.; Groeneveld, G. J.; Cooper, A. A.
MOVEMENT DISORDERS 36 (6) :1468-1470, 2021 10.1002/mds.28620
Potent PDE4 inhibitor activates AMPK and Sirt1 to induce mitochondrial biogenesis
Park, S. J.; Ahmad, F.; Bahde, R. J.; Philp, A.; Kim, J.; Huang, T.; Kim, M. K.; Trenkle, W. C.; Chung, J. H.
PLoS One 16 (6) :e0253269, 2021 10.1371/journal.pone.0253269
Ninjin'yoeito modulates feeding and activity under negative energy balance conditions via the NPY system
Zhang, L.; Clark, T.; Gopalasingam, G.; Neely, G. G.; Herzog, H.
NEUROPEPTIDES 87 :102149, 2021 10.1016/j.npep.2021.102149
SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
V. Sancho-Shimizu, P. Brodin, A. Cobat, C.M. Biggs, J. Toubiana, C.L. Lucas, S.E. Henrickson, A. Belot, , S.G. Tangye, J.D. Milner, M. Levin, L. Abel, D. Bogunovic, J.L. Casanova, and S.Y. Zhang
JOURNAL OF EXPERIMENTAL MEDICINE 218 (6) 2021 10.1084/jem.20210446
Low repeatability of aversive learning in zebrafish (Danio rerio)
Mason, D.; Zajitschek, S.; Anwer, H.; O'Dea, R. E.; Hesselson, D.; Nakagawa, S.
JOURNAL OF EXPERIMENTAL BIOLOGY 224 (11) 2021 10.1242/jeb.240846
Transcriptome analysis of islets from diabetes-resistant and diabetes-prone obese mice reveals novel gene regulatory networks involved in beta-cell compensation and failure
Chan, J. Y.; Bensellam, M.; Lin, R. C. Y.; Liang, C.; Lee, K.; Jonas, J. C.; Laybutt, D. R.
FASEB JOURNAL 35 (6) :e21608, 2021 10.1096/fj.202100009R
An efficient new assay for measuring zebrafish anxiety: Tall tanks that better characterize between-individual differences
Anwer, H.; Mason, D.; Zajitschek, S.; Noble, D. W. A.; Hesselson, D.; Morris, M. J.; Lagisz, M.; Nakagawa, S.
JOURNAL OF NEUROSCIENCE METHODS 356 :109138, 2021 10.1016/j.jneumeth.2021.109138
CD8(+) T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
Hensen, L.; Illing, P. T.; Bridie Clemens, E.; Nguyen, T. H. O.; Koutsakos, M.; van de Sandt, C. E.; Mifsud, N. A. Nguyen, A. T.; Szeto, C.; Chua, B. Y.; Halim, H.; Rizzetto, S.; Luciani, F.; Loh, L.; Grant, E. J.; Saunders, P. M.; Brooks, A. G.; Rockman, S.; Kotsimbos, T. C.; Cheng, A. C.; Richards, M.; Westall, G. P.; Wakim, L. M.; Loudovaris, T.; Mannering, S. I.; Elliott, M.; Tangye, S. G.; Jackson, D. C.; Flanagan, K. L.; Rossjohn, J.; Gras, S.; Davies, J.; Miller, A.; Tong, S. Y. C.; Purcell, A. W.; Kedzierska, K.
Nature Communications 12 (1) :2931, 2021 10.1038/s41467-021-23212-x
DNA methylation profiles unique to Kalahari KhoeSan individuals
Goncearenco, A.; LaBarre, B. A.; Petrykowska, H. M.; Jaratlerdsiri, W.; Bornman, M. S. R.; Turner, S. D.; Hayes, V. M.; Elnitski, L.
Epigenetics :1-17, 2021 10.1080/15592294.2020.1809852
Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures
Begik, O.; Lucas, M. C.; Liu, H.; Ramirez, J. M.; Mattick, J. S.; Novoa, E. M.
GENOME BIOLOGY 21 (1) :97, 2021 10.1186/s13059-020-02009-z
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies
Rouet, R. Mazigi, O. Walker, G. J. Langley, D. B. Sobti, M. Schofield, P. Lenthall, H. Jackson, J. Ubiparipovic, S. Henry, J. Y. Abayasingam, A. Burnett, D. Kelleher, A. Brink, R. Bull, R. A. Turville, S. Stewart, A. G. Goodnow, C. C. Rawlinson, W. D. Christ, D.
mAbs 13 (1) :1922134, 2021 10.1080/19420862.2021.1922134
Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease
Watt, K. I.; Henstridge, D. C.; Ziemann, M.; Sim, C. B.; Montgomery, M. K.; Samocha-Bonet, D.; Parker, B. L.; Dodd, G. T.; Bond, S. T.; Salmi, T. M.; Lee, R. S.; Thomson, R. E.; Hagg, A.; Davey, J. R.; Qian, H.; Koopman, R.; El-Osta, A.; Greenfield, J. R.; Watt, M. J.; Febbraio, M. A.; Drew, B. G.; Cox, A. G.; Porrello, E. R.; Harvey, K. F.; Gregorevic, P.
Nature Communications 12 (1) :2887, 2021 10.1038/s41467-021-23240-7
Quantitative profiling of pseudouridylation dynamics in native RNAs with nanopore sequencing
Begik, O.; Lucas, M. C.; Pryszcz, L. P.; Ramirez, J. M.; Medina, R.; Milenkovic, I.; Cruciani, S.; Liu, H.; Vieira, H. G. S.; Sas-Chen, A.; Mattick, J. S.; Schwartz, S.; Novoa, E. M.
NATURE BIOTECHNOLOGY 2021 10.1038/s41587-021-00915-6