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Metformin Use Is Associated With Slowed Cognitive Decline and Reduced Incident Dementia in Older Adults With Type 2 Diabetes: The Sydney Memory and Ageing Study
Samaras, K.; Makkar, S.; Crawford, J. D.; Kochan, N. A.; Wen, W.; Draper, B.; Trollor, J. N.; Brodaty, H.; Sachdev, P. S.
DIABETES CARE 43 (11) :2691-2701, 2020 10.2337/dc20-0892
High-dose leucine supplementation does not prevent muscle atrophy or strength loss over 7 days of immobilization in healthy young males
Edwards, S. J.; Smeuninx, B.; McKendry, J.; Nishimura, Y.; Luo, D.; Marshall, R. N.; Perkins, M.; Ramsay, J.; Joanisse, S.; Philp, A.; Breen, L.
AMERICAN JOURNAL OF CLINICAL NUTRITION 112 (5) :1368-1381, 2020 10.1093/ajcn/nqaa229
A novel homozygous KY variant causing a complex neurological disorder
Arif, B.; Rasheed, A.; Kumar, K.R.; Fatima, A.; Abbas, G.; Wohler, E.; Sobriera, N.; Lohmann, K.; Naz, S.
European Journal of Medical Genetics 63 (11) :104031, 2020 https://doi.org/10.1016/j.ejmg.2020.104031
Spatial and Temporal Control of CRISPR-Cas9-Mediated Gene Editing Delivered via a Light-Triggered Liposome System
Aksoy, Y. A.; Yang, B.; Chen, W.; Hung, T.; Kuchel, R. P.; Zammit, N. W.; Grey, S. T.; Goldys, E. M.; Deng, W.
ACS Applied Materials & Interfaces 12 (47) :52433-52444, 2020 10.1021/acsami.0c16380
Benchmarking of cell type deconvolution pipelines for transcriptomics data
Cobos, F. A.; Alquicira-Hernandez, J.; Powell, J. E.; Mestdagh, P.; De Preter, K.
Nature Communications 11 (1) :6291, 2020 10.1038/s41467-020-20288-9
Analytical Guidelines for co-fractionation Mass Spectrometry Obtained through Global Profiling of Gold Standard Saccharomyces cerevisiae Protein Complexes
Pang, C. N. I.; Ballouz, S.; Weissberger, D.; Thibaut, L. M.; Hamey, J. J.; Gillis, J.; Wilkins, M. R.; Hart-Smith, G.
MOLECULAR & CELLULAR PROTEOMICS 19 (11) :1876-1895, 2020 10.1074/mcp.RA120.002154
Fats and Mets, KRAS-Driven Lipid Dysregulation Affects Metastatic Potential in Pancreatic Cancer
Man, J.; Pajic, M.; Joshua, A. M.
CANCER RESEARCH 80 (22) :4886-4887, 2020 10.1158/0008-5472.CAN-20-3082
Case Report: A Case of Pituitary Carcinoma Treated With Sequential Dual Immunotherapy and Vascular Endothelial Growth Factor Inhibition Therapy
Lamb, L. S.; Sim, H. W.; McCormack, A. I.
Frontiers in Endocrinology 11 :576027, 2020 10.3389/fendo.2020.576027
The complex relationship between genotype, pathology and phenotype in familial dementia
Kwok, J. B.; Loy, C. T.; Dobson-Stone, C.; Halliday, G. M.
NEUROBIOLOGY OF DISEASE 145 :105082, 2020 10.1016/j.nbd.2020.105082
Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism
Hoffman, N. J.; Whitfield, J.; Janzen, N. R.; Belhaj, M. R.; Galic, S.; Murray-Segal, L.; Smiles, W. J.; Ling, N. X. Y.; Dite, T. A.; Scott, J. W.; Oakhill, J. S.; Brink, R.; Kemp, B. E.; Hawley, J. A.
Molecular Metabolism 41 :101048, 2020 10.1016/j.molmet.2020.101048
Changes to bone mineral density, the trabecular bone score and hip structural analysis following parathyroidectomy: a case report
Lin, R.; Vucak-Dzumhur, M.; Elder, G. J.
BMC Nephrology 21 (1) :513, 2020 10.1186/s12882-020-02168-y
PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis
Srijakotre, N.; Liu, H. J.; Nobis, M.; Man, J.; Yip, H. Y. K.; Papa, A.; Abud, H. E.; Anderson, K. I.; Welch, H. C. E.; Tiganis, T.; Timpson, P.; McLean, C. A.; Ooms, L. M.; Mitchell, C. A.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (45) :28056-28067, 2020 10.1073/pnas.2006445117
A zebrafish functional genomics model to investigate the role of human A20 variants in vivo
Cultrone, D.; Zammit, N. W.; Self, E.; Postert, B.; Han, J. Z. R.; Bailey, J.; Warren, J.; Croucher, D. R.; Kikuchi, K.; Bogdanovic, O.; Chtanova, T.; Hesselson, D.; Grey, S. T.
Scientific Reports 10 (1) :19085, 2020 10.1038/s41598-020-75917-6.
Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network
Demetri, G. D.; Antonescu, C. R.; Bjerkehagen, B.; Bovee, Jvmg; Boye, K.; Chacon, M.; Dei Tos, A. P.; Desai, J.; Fletcher, J. A.; Gelderblom, H.; George, S.; Gronchi, A.; Haas, R. L.; Hindi, N.; Hohenberger, P.; Joensuu, H.; Jones, R. L.; Judson, I.; Kang, Y. K.; Kawai, A.; Lazar, A. J.; Le Cesne, A.; Maestro, R.; Maki, R. G.; Martin, J.; Patel, S.; Penault-Llorca, F.; Premanand Raut, C.; Rutkowski, P.; Safwat, A.; Sbaraglia, M.; Schaefer, I. M.; Shen, L.; Serrano, C.; Schoffski, P.; Stacchiotti, S.; Sundby Hall, K.; Tap, W. D.; Thomas, D. M.; Trent, J.; Valverde, C.; van der Graaf, W. T. A.; von Mehren, M.; Wagner, A.; Wardelmann, E.; Naito, Y.; Zalcberg, J.; Blay, J. Y.
Annals Of Oncology 31 (11) :1506-1517, 2020 10.1016/j.annonc.2020.08.2232
Loss-of-Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities
Steel, D.; Zech, M.; Zhao, C.; Barwick, K. E. S.; Burke, D.; Demailly, D.; Kumar, K. R.; Zorzi, G.; Nardocci, N.; Kaiyrzhanov, R.; Wagner, M.; Iuso, A.; Berutti, R.; Skorvanek, M.; Necpal, J.; Davis, R.; Wiethoff, S.; Mankad, K.; Sudhakar, S.; Ferrini, A.; Sharma, S.; Kamsteeg, E. J.; Tijssen, M. A.; Verschuuren, C.; van Egmond, M. E.; Flowers, J. M.; McEntagart, M.; Tucci, A.; Coubes, P.; Bustos, B. I.; Gonzalez-Latapi, P.; Tisch, S.; Darveniza, P.; Gorman, K. M.; Peall, K. J.; Botzel, K.; Koch, J. C.; Kmiec, T.; Plecko, B.; Boesch, S.; Haslinger, B.; Jech, R.; Garavaglia, B.; Wood, N.; Houlden, H.; Gissen, P.; Lubbe, S. J.; Sue, C. M.; Cif, L.; Mencacci, N. E.; Anderson, G.; Kurian, M. A.; Winkelmann, J.; Genomics England Research, Consortium
ANNALS OF NEUROLOGY 88 (5) :867-877, 2020 10.1002/ana.25879