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99 items matching your search terms.
OpenAccess publication Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer
Owens, T. W.; Rogers, R. L.; Best, S.; Ledger, A.; Mooney, A. M.; Ferguson, A.; Shore, P.; Swarbrick, A.; Ormandy, C. J.; Simpson, P. T.; Carroll, J. S.; Visvader, J. E.; Naylor, M. J.;
OpenAccess publication c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer
Nair, R.; Roden, D. L.; Teo, W. S.; McFarland, A.; Junankar, S.; Ye, S.; Nguyen, A.; Yang, J.; Nikolic, I.; Hui, M.; Morey, A.; Shah, J.; Pfefferle, A. D.; Usary, J.; Selinger, C.; Baker, L. A.; Armstrong, N.; Cowley, M. J.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Herschkowitz, J. I.; Perou, C. M.; Kaplan, W.; O'Toole, S. A.; Swarbrick, A
ONCOGENE 33 (30) :3992-4002, 2014
OpenAccess publication The mammary cellular hierarchy and breast cancer
Oakes, S. R.; Gallego-Ortega, D.; Ormandy, C. J.;
OpenAccess publication Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease
Hilton, H. N.; Doan, T. B.; Graham, J. D.; Oakes, S. R.; Silvestri, A.; Santucci, N.; Kantimm, S.; Huschtscha, L. I.; Ormandy, C. J.; Funder, J. W.; Simpson, E. R.; Kuczek, E. S.; Leedman, P. J.; Tilley, W. D.; Fuller, P. J.; Muscat, G. E.; Clarke, C. L.;
Oncotarget 5 (18) :8651-64, 2014
OpenAccess publication BCL-2 hypermethylation is a potential biomarker of sensitivity to anti-mitotic chemotherapy in endocrine-resistant breast cancer.
Stone, A.; Cowley, M.J.; Valdes-Mora, F.; McCloy, R.; Sergio, C.M.; Gallego-Ortega, D.; Caldon, C. E.; Ormandy, C.J.; Biankin, A.V.; Gee, J. M.; Nicholson, R. I.; Print, C.G.; Clark, S.J.; and Musgrove, E.A.;
OpenAccess publication Functional characterization of cancer-associated Gab1 mutations.
Ortiz-Padilla, C.; Gallego-Ortega, D.; Browne, B. C.; Hochgrafe, F.; Caldon, C. E.; Lyons, R. J.; Croucher, D. R.; Rickwood, D.; Ormandy, C. J.; Brummer, T.; Daly, R. J.
ONCOGENE 2013 10.1038/onc.2012.271 onc2012271 [pii]
OpenAccess publication Progesterone drives mammary secretory differentiation via RankL-induction of Elf5 in luminal progenitor cells.
Lee, H.J.; Gallego-Ortega, D.; Ledger, A.; Schramek, D.; Joshi, P.; Szwarc, M.M.; Cho, C.; Lydon, J.P.; Khokka, R.; Penninger, J.; Ormandy, C.J.;
DEVELOPMENT :1397-1401, 2013 10.1242/dev.088948
OpenAccess publication ELF5 supresses estrogen sensitivity and underpins the acquisition of anitestrogen resistance in luminal breast cancer.
Kalyuga, M.; Gallego-Ortega, D.; Lee, H. J.; Roden, D. L.; Cowley, M. J.; Caldon, C. E.; Stone, A.; Allerdice, S. L.; Valdes-Mora, F.; Launchbury, R.; Statham, A. L.; Armstrong, N.; Alles, M. C.; Young, A.; Egger, A.; Au, W.; Piggin, C. L.; Evans, C. J.; Ledger, A.; Brummer, T.; Oakes, S. R.; Kaplan, W.; Gee, J. M.; Nicholson, R. I.; Sutherland, R. L.; Swarbrick, A.; Naylor, M. J.; Clark, S. J.; Carroll, J. S.; Ormandy, C. J.;
PLOS BIOL 10 (12) :e1001461, 2012 10.1371/journal.pbio.1001461
OpenAccess publication RAB-Like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly
Lo, J. C.; Jamsai, D.; O'Connor, A. E.; Borg, C.; Clark, B. J.; Whisstock, J. C.; Field, M. C.; Adams, V.; Ishikawa, T.; Aitken, R. J.; Whittle, B.; Goodnow, C. C.; Ormandy, C. J.; O'Bryan, M. K.;
PLOS GENET 8 (10) :e1002969, 2012 10.1371/journal.pgen.1002969
OpenAccess publication An essential role for Katanin p80 and microtubule severing in male gamete production.
O'Donnell, L.; Rhodes, D.; Smith, S. J.; Merriner, D. J.; Clark, B. J.; Borg, C.; Whittle, B.; O'Connor, A. E.; Smith, L. B.; McNally, F. J.; de Kretser, D. M.; Goodnow, C. C.; Ormandy, C. J.; Jamsai, D.; O'Bryan, M. K.;
PLOS GENET 8 (5) :e1002698, 2012 10.1371/journal.pgen.1002698
OpenAccess publication Interplay between progesterone and prolactin in mammary development and implications for breast cancer.
Lee, H.J.; Ormandy, C.J.
MOLECULAR AND CELLULAR ENDOCRINOLOGY 357 (1-2) :101-107, 2012 10.1016/j.mce.2011.09.020
OpenAccess publication Grb10 regulates the development of fiber number in skeletal muscle.
Holt, L.J.; Turner, N.; Mokbel, N.; Trefely, S.; Kanzleiter, T.; Kaplan, W.; Ormandy, C.J.; Daly, R.J.; Cooney, G.J.;
FASEB JOURNAL 26 (9) :3658-3669, 2012 10.1096/fj.11-199349
OpenAccess publication Elf5, hormones and cell fate.
Lee, H.J.; Ormandy, C.J.
TRENDS IN ENDOCRINOLOGY AND METABOLISM 23 (6) :292-298, 2012 S1043-2760(12)00033-1 [pii] 10.1016/j.tem.2012.02.006
OpenAccess publication Lineage specific methylation of the Elf5 promoter in mammary epithelial cells.
Lee, H.J.; Hinshelwood, R.A.; Bouras, T.; Gallego-Ortega, D.; Valdes-Mora, F.; Blazek, K.; Visvader, J.E.; Clark, S.J.; Ormandy, C.J.
STEM CELLS 29 (10) :1611-9, 2011
OpenAccess publication Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer
O'Toole, S. A.; Machalek, D. A.; Shearer, R. F.; Millar, E. K.; Nair, R.; Schofield, P.; McLeod, D.; Cooper, C. L.; McNeil, C. M.; McFarland, A.; Nguyen, A.; Ormandy, C. J.; Qiu, M. R.; Rabinovich, B.; Martelotto, L. G.; Vu, D.; Hannigan, G. E.; Musgrove, E. A.; Christ, D.; Sutherland, R. L.; Watkins, D. N.; Swarbrick, A.;
CANCER RESEARCH 71 (11) :4002-4014, 2011 0008-5472.CAN-10-3738 [pii] 10.1158/0008-5472.CAN-10-3738