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136 items matching your search terms.
OpenAccess publication Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation
Hoy, A. J.;Bruce, C. R.;Cederberg, A.;Turner, N.;James, D. E.;Cooney, G. J.;Kraegen, E. W. :
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 293 (5) :E1358-64, 2007
OpenAccess publication Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life
Smith, F. M.;Holt, L. J.;Garfield, A. S.;Charalambous, M.;Koumanov, F.;Perry, M.;Bazzani, R.;Sheardown, S. A.;Hegarty, B. D.;Lyons, R. J.;Cooney, G. J.;Daly, R. J.;Ward, A. :
MOLECULAR AND CELLULAR BIOLOGY 27 (16) :5871-86, 2007
OpenAccess publication Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression
Cleasby, M. E.;Reinten, T. A.;Cooney, G. J.;James, D. E.;Kraegen, E. W. :
MOLECULAR ENDOCRINOLOGY 21 (1) :215-28, 2007
OpenAccess publication Inhibition of PKCvarepsilon improves glucose-stimulated insulin secretion and reduces insulin clearance
Schmitz-Peiffer, C.;Laybutt, D. R.;Burchfield, J. G.;Gurisik, E.;Narasimhan, S.;Mitchell, C. J.;Pedersen, D. J.;Braun, U.;Cooney, G. J.;Leitges, M.;Biden, T. J. :
Cell Metabolism 6 (4) :320-8, 2007
OpenAccess publication Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
Turner, N.;Bruce, C. R.;Beale, S. M.;Hoehn, K. L.;So, T.;Rolph, M. S.;Cooney, G. J. :
DIABETES 56 (8) :2085-92, 2007
Casitas b-lineage lymphoma-deficient mice are protected against high-fat diet-induced obesity and insulin resistance
Molero, J. C.;Waring, S. G.;Cooper, A.;Turner, N.;Laybutt, R.;Cooney, G. J.;James, D. E. :
DIABETES 55 (3) :708-15, 2006
Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action
Molero, J. C.;Turner, N.;Thien, C. B.;Langdon, W. Y.;James, D. E.;Cooney, G. J. :
DIABETES 55 (12) :3411-7, 2006
OpenAccess publication Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats
Kraegen, E. W.;Saha, A. K.;Preston, E.;Wilks, D.;Hoy, A. J.;Cooney, G. J.;Ruderman, N. B. :
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 290 (3) :E471-9, 2006
Y2Y4 receptor double knockout protects against obesity due to a high-fat diet or Y1 receptor deficiency in mice
Sainsbury, A.;Bergen, H. T.;Boey, D.;Bamming, D.;Cooney, G. J.;Lin, S.;Couzens, M.;Stroth, N.;Lee, N. J.;Lindner, D.;Singewald, N.;Karl, T.;Duffy, L.;Enriquez, R.;Slack, K.;Sperk, G.;Herzog, H. :
DIABETES 55 (1) :19-26, 2006
Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells and rodent liver in vivo
Parkes, H. A.;Preston, E.;Wilks, D.;Ballesteros, M.;Carpenter, L.;Wood, L.;Kraegen, E. W.;Furler, S. M.;Cooney, G. J. :
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 291 (4) :E737-44, 2006
Acute bidirectional manipulation of muscle glucose uptake by in vivo electrotransfer of constructs targeting glucose transporter genes
Cleasby, M. E.;Davey, J. R.;Reinten, T. A.;Graham, M. W.;James, D. E.;Kraegen, E. W.;Cooney, G. J. :
DIABETES 54 (9) :2702-11, 2005
Both saturated and n-6 polyunsaturated fat diets reduce phosphorylation of insulin receptor substrate-1 and protein kinase B in muscle during the initial stages of in vivo insulin stimulation
Frangioudakis, G.;Ye, J. M.;Cooney, G. J. :
ENDOCRINOLOGY 146 (12) :5596-603, 2005
Nur77 regulates lipolysis in skeletal muscle cells. Evidence for cross-talk between the beta-adrenergic and an orphan nuclear hormone receptor pathway
Maxwell, M. A.;Cleasby, M. E.;Harding, A.;Stark, A.;Cooney, G. J.;Muscat, G. E. :
JOURNAL OF BIOLOGICAL CHEMISTRY 280 (13) :12573-84, 2005
Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin
Ye, J. M.;Dzamko, N.;Cleasby, M. E.;Hegarty, B. D.;Furler, S. M.;Cooney, G. J.;Kraegen, E. W. :
DIABETOLOGIA 47 (7) :1306-13, 2004
Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice
Cooney, G. J.;Lyons, R. J.;Crew, A. J.;Jensen, T. E.;Molero, J. C.;Mitchell, C. J.;Biden, T. J.;Ormandy, C. J.;James, D. E.;Daly, R. J. :
EMBO JOURNAL 23 (3) :582-93, 2004