Publications

Publications Search

Search for publications by author
Search for publications by abstract keyword(s)

Search results

110 items matching your search terms.
Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability
Burnett, D. L.; Jackson, K. J. L.; Langley, D. B.; Aggrawal, A.; Stella, A. O.; Johansen, M. D.; Balachandran, H.; Lenthall, H.; Rouet, R.; Walker, G.; Saunders, B. M.; Singh, M.; Li, H.; Henry, J. Y.; Jackson, J.; Stewart, A. G.; Witthauer, F.; Spence, M. A.; Hansbro, N. G.; Jackson, C.; Schofield, P.; Milthorpe, C.; Martinello, M.; Schulz, S. R.; Roth, E.; Kelleher, A.; Emery, S.; Britton, W. J.; Rawlinson, W. D.; Karl, R.; Schafer, S.; Winkler, T. H.; Brink, R.; Bull, R. A.; Hansbro, P. M.; Jack, H. M.; Turville, S.; Christ, D.; Goodnow, C. C.
IMMUNITY 54 (12) :2908-2921 e6, 2021 10.1016/j.immuni.2021.10.019
The unique biology of germinal center B cells
Young, C.; Brink, R.
IMMUNITY 54 (8) :1652-1664, 2021 10.1016/j.immuni.2021.07.015
Positive selection of IgG(+) over IgM(+) B cells in the germinal center reaction
Sundling, C.; Lau, A. W. Y.; Bourne, K.; Young, C.; Laurianto, C.; Hermes, J. R.; Menzies, R. J.; Butt, D.; Krautler, N. J.; Zahra, D.; Suan, D.; Brink, R.
INFECTION AND IMMUNITY 54 (5) :988-1001, 2021 10.1016/j.immuni.2021.03.013
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies
Rouet, R.; Mazigi, O.; Walker, G. J.; Langley, D. B.; Sobti, M.; Schofield, P.; Lenthall, H.; Jackson, J.; Ubiparipovic, S.; Henry, J. Y.; Abayasingam, A.; Burnett, D.; Kelleher, A.; Brink, R.; Bull, R. A.; Turville, S.; Stewart, A. G.; Goodnow, C. C.; Rawlinson, W. D.; Christ, D.
mAbs 13 (1) :1922134, 2021 10.1080/19420862.2021.1922134
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
Youlten, S. E.; Kemp, J. P.; Logan, J. G.; Ghirardello, E. J.; Sergio, C. M.; Dack, M. R. G.; Guilfoyle, S. E.; Leitch, V. D.; Butterfield, N. C.; Komla-Ebri, D.; Chai, R. C.; Corr, A. P.; Smith, J. T.; Mohanty, S. T.; Morris, J. A.; McDonald, M. M.; Quinn, J. M. W.; McGlade, A. R.; Bartonicek, N.; Jansson, M.; Hatzikotoulas, K.; Irving, M. D.; Beleza-Meireles, A.; Rivadeneira, F.; Duncan, E.; Richards, J. B.; Adams, D. J.; Lelliott, C. J.; Brink, R.; Phan, T. G.; Eisman, J. A.; Evans, D. M.; Zeggini, E.; Baldock, P. A.; Bassett, J. H. D.; Williams, G. R.; Croucher, P. I.
Nature Communications 12 (1) :2444, 2021 10.1038/s41467-021-22517-1
Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice
Masle-Farquhar, E.; Russell, A.; Li, Y.; Zhu, F.; Rui, L.; Brink, R.; Goodnow, C. C.
PLoS One 16 (4) :e0237830, 2021 10.1371/journal.pone.0237830
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
McDonald, M. M.; Khoo, W. H.; Ng, P. Y.; Xiao, Y.; Zamerli, J.; Thatcher, P.; Kyaw, W.; Pathmanandavel, K.; Grootveld, A. K.; Moran, I.; Butt, D.; Nguyen, A.; Corr, A.; Warren, S.; Biro, M.; Butterfield, N. C.; Guilfoyle, S. E.; Komla-Ebri, D.; Dack, M. R. G.; Dewhurst, H. F.; Logan, J. G.; Li, Y.; Mohanty, S. T.; Byrne, N.; Terry, R. L.; Simic, M. K.; Chai, R.; Quinn, J. M. W.; Youlten, S. E.; Pettitt, J. A.; Abi-Hanna, D.; Jain, R.; Weninger, W.; Lundberg, M.; Sun, S.; Ebetino, F. H.; Timpson, P.; Lee, W. M.; Baldock, P. A.; Rogers, M. J.; Brink, R.; Williams, G. R.; Bassett, J. H. D.; Kemp, J. P.; Pavlos, N. J.; Croucher, P. I.; Phan, T. G.
CELL 184 (5) :1330-1347 e13, 2021 10.1016/j.cell.2021.02.002
BAFFR controls early memory B cell responses but is dispensable for germinal center function
Lau, A.W.Y.; Turner, V.M.; Bourne, K.; Hermes, J.R.; Chan, T.D.; Brink, R.
JOURNAL OF EXPERIMENTAL MEDICINE 218 (2) 2021
Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism
Hoffman, N. J.; Whitfield, J.; Janzen, N. R.; Belhaj, M. R.; Galic, S.; Murray-Segal, L.; Smiles, W. J.; Ling, N. X. Y.; Dite, T. A.; Scott, J. W.; Oakhill, J. S.; Brink, R.; Kemp, B. E.; Hawley, J. A.
Molecular Metabolism 41 :101048, 2020 10.1016/j.molmet.2020.101048
Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens
Burnett, D. L.; Schofield, P.; Langley, D. B.; Jackson, J.; Bourne, K.; Wilson, E.; Porebski, B. T.; Buckle, A. M.; Brink, R.; Goodnow, C. C.; Christ, D.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (36) :22341-22350, 2020 10.1073/pnas.2005102117
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage
Toboso-Navasa, A.; Gunawan, A.; Morlino, G.; Nakagawa, R.; Taddei, A.; Damry, D.; Patel, Y.; Chakravarty, P.; Janz, M.; Kassiotis, G.; Brink, R.; Eilers, M.; Calado, D. P.
JOURNAL OF EXPERIMENTAL MEDICINE 217 (7) 2020 10.1084/jem.20191933
A Future Outlook on Molecular Mechanisms of Immunity
Weinmann, A. S.; Youngblood, B. A.; Smale, S. T.; Brink, R.; Schatz, D. G.; McHeyzer-Williams, M.
TRENDS IN IMMUNOLOGY 41 (7) :549-555, 2020 10.1016/j.it.2020.05.005
Germinal centers and autoantibodies
Young, C.; Brink, R.
IMMUNOLOGY AND CELL BIOLOGY 98 (6) :480-489, 2020 10.1111/imcb.12321
Selection in the germinal center
Lau, A. W.; Brink, R.
CURRENT OPINION IN IMMUNOLOGY 63 :29-34, 2020 10.1016/j.coi.2019.11.001
Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody
Singh, M.; Jackson, K. J. L.; Wang, J. J.; Schofield, P.; Field, M. A.; Koppstein, D.; Peters, T. J.; Burnett, D. L.; Rizzetto, S.; Nevoltris, D.; Masle-Farquhar, E.; Faulks, M. L.; Russell, A.; Gokal, D.; Hanioka, A.; Horikawa, K.; Colella, A. D.; Chataway, T. K.; Blackburn, J.; Mercer, T. R.; Langley, D. B.; Goodall, D. M.; Jefferis, R.; Gangadharan Komala, M.; Kelleher, A. D.; Suan, D.; Rischmueller, M.; Christ, D.; Brink, R.; Luciani, F.; Gordon, T. P.; Goodnow, C. C.; Reed, J. H.
CELL 180 (5) :878-894 e19, 2020 10.1016/j.cell.2020.01.029
OpenAccess publication Activated PI3Kdelta breaches multiple B cell tolerance checkpoints and causes autoantibody production
Lau, A.; Avery, D. T.; Jackson, K.; Lenthall, H.; Volpi, S.; Brigden, H.; Russell, A. J.; Bier, J.; Reed, J. H.; Smart, J. M.; Cole, T.; Choo, S.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Uzel, G.; Notarangelo, L. D.; Brink, R.; Goodnow, C. C.; Tangye, S. G.; Deenick, E. K.
JOURNAL OF EXPERIMENTAL MEDICINE 217 (2) :e20191336, 2020 10.1084/jem.20191336