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136 items matching your search terms.
Treatment of type 2 diabetes with the designer cytokine IC7Fc
Findeisen, M.; Allen, T. L.; Henstridge, D. C.; Kammoun, H.; Brandon, A. E.; Baggio, L. L.; Watt, K. I.; Pal, M.; Cron, L.; Estevez, E.; Yang, C.; Kowalski, G. M.; O'Reilly, L.; Egan, C.; Sun, E.; Thai, L. M.; Krippner, G.; Adams, T. E.; Lee, R. S.; Grotzinger, J.; Garbers, C.; Risis, S.; Kraakman, M. J.; Mellet, N. A.; Sligar, J.; Kimber, E. T.; Young, R. L.; Cowley, M. A.; Bruce, C. R.; Meikle, P. J.; Baldock, P. A.; Gregorevic, P.; Biden, T. J.; Cooney, G. J.; Keating, D. J.; Drucker, D. J.; Rose-John, S.; Febbraio, M. A.
NATURE 574 (7776) :63-68, 2019 10.1038/s41586-019-1601-9
Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance
Brandon, A. E.; Liao, B. M.; Diakanastasis, B.; Parker, B. L.; Raddatz, K.; McManus, S. A.; O'Reilly, L.; Kimber, E.; van der Kraan, A. G.; Hancock, D.; Henstridge, D. C.; Meikle, P. J.; Cooney, G. J.; James, D. E.; Reibe, S.; Febbraio, M. A.; Biden, T. J.; Schmitz-Peiffer, C.
Cell Metabolism 29 (1) :183-191 e7, 2019 10.1016/j.cmet.2018.09.013
Thermoneutral housing does not influence fat mass or glucose homeostasis in C57BL/6 mice
Small, L.; Gong, H.; Yassmin, C.; Cooney, G. J.; Brandon, A. E.
JOURNAL OF ENDOCRINOLOGY 239 (3) :313-324, 2018 10.1530/JOE-18-0279
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism
Turner, N.; Lim, X. Y.; Toop, H. D.; Osborne, B.; Brandon, A. E.; Taylor, E. N.; Fiveash, C. E.; Govindaraju, H.; Teo, J. D.; McEwen, H. P.; Couttas, T. A.; Butler, S. M.; Das, A.; Kowalski, G. M.; Bruce, C. R.; Hoehn, K. L.; Fath, T.; Schmitz-Peiffer, C.; Cooney, G. J.; Montgomery, M. K.; Morris, J. C.; Don, A. S.
Nature Communications 9 (1) :3165, 2018 10.1038/s41467-018-05613-7
OpenAccess publication Modelling insulin resistance in rodents by alterations in diet. What have "high fat" and high calorie diets revealed?
Small, L.; Brandon, A. E.; Turner, N.; Cooney, G. J.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 314 (3) :E251-E265, 2018 10.1152/ajpendo.00337.2017
OpenAccess publication Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice
Holt, L. J.; Brandon, A. E.; Small, L.; Suryana, E.; Preston, E.; Wilks, D.; Mokbel, N.; Coles, C. A.; White, J. D.; Turner, N.; Daly, R. J.; Cooney, G. J.
ENDOCRINOLOGY 159 (3) :1339-1351, 2018 10.1210/en.2017-00851
OpenAccess publication High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice
Burchfield, J. G.; Kebede, M. A.; Meoli, C. C.; Stockli, J.; Whitworth, P. T.; Wright, A. L.; Hoffman, N. J.; Minard, A. Y.; Ma, X.; Krycer, J. R.; Nelson, M. E.; Tan, S. X.; Yau, B.; Thomas, K. C.; Wee, N. K. Y.; Khor, E. C.; Enriquez, R. F.; Vissel, B.; Biden, T. J.; Baldock, P. A.; Hoehn, K. L.; Cantley, J.; Cooney, G. J.; James, D. E.; Fazakerley, D. J.
JOURNAL OF BIOLOGICAL CHEMISTRY 293 (15) :5731-5745, 2018 10.1074/jbc.RA117.000808
OpenAccess publication Metabolomic analysis of insulin resistance across different mouse strains and diets
Stockli, J.; Fisher-Wellman, K. H.; Chaudhuri, R.; Zeng, X. Y.; Fazakerley, D. J.; Meoli, C. C.; Thomas, K. C.; Hoffman, N. J.; Mangiafico, S. P.; Xirouchaki, C. E.; Yang, C. H.; Ilkayeva, O.; Wong, K.; Cooney, G. J.; Andrikopoulos, S.; Muoio, D. M.; James, D. E.
JOURNAL OF BIOLOGICAL CHEMISTRY 292 (47) :19135-19145, 2017 10.1074/jbc.M117.818351
OpenAccess publication Association of muscle lipidomic profile with high-fat diet-induced insulin resistance across five mouse strains
Montgomery, M. K.; Brown, S. H. J.; Mitchell, T. W.; Coster, A. C. F.; Cooney, G. J.; Turner, N.
Scientific Reports 7 (1) :13914, 2017 10.1038/s41598-017-14214-1
OpenAccess publication Effects of feeding time on daily rhythms of neuropeptide and clock gene expression in the rat hypothalamus
Wang, D.; Opperhuizen, A. L.; Reznick, J.; Turner, N.; Su, Y.; Cooney, G. J.; Kalsbeek, A.
Brain Research 1671 :93-101, 2017 10.1016/j.brainres.2017.07.006
OpenAccess publication Exploring the relationship between alpha-actinin-3 deficiency and obesity in mice and humans
Houweling, P. J.; Berman, Y. D.; Turner, N.; Quinlan, K. G. R.; Seto, J. T.; Yang, N.; Lek, M.; Macarthur, D. G.; Cooney, G.; North, K. N.
INTERNATIONAL JOURNAL OF OBESITY 41 (7) :1154-1157, 2017 10.1038/ijo.2017.72
OpenAccess publication Insulin controls food intake and energy balance via NPY neurons
Loh, K.; Zhang, L.; Brandon, A.; Wang, Q.; Begg, D.; Qi, Y.; Fu, M.; Kulkarni, R.; Teo, J.; Baldock, P.; Bruning, J. C.; Cooney, G.; Neely, G.; Herzog, H.
Molecular Metabolism 6 (6) :574-584, 2017 10.1016/j.molmet.2017.03.013
OpenAccess publication Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver
Nagarajan, S. R.; Brandon, A. E.; McKenna, J. A.; Shtein, H. C.; Nguyen, T. Q.; Suryana, E.; Poronnik, P.; Cooney, G. J.; Saunders, D. N.; Hoy, A. J.
PLoS One 12 (3) :e0174431, 2017 10.1371/journal.pone.0174431
OpenAccess publication Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes
Minard, A. Y.; Wong, M. K.; Chaudhuri, R.; Tan, S. X.; Humphrey, S. J.; Parker, B. L.; Yang, J. Y.; Laybutt, D. R.; Cooney, G. J.; Coster, A. C.; Stockli, J.; James, D. E.;
JOURNAL OF BIOLOGICAL CHEMISTRY 291 (49) :25629-25640, 2016
Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species
Montgomery, M. K.; Brown, S. H.; Lim, X. Y.; Fiveash, C. E.; Osborne, B.; Bentley, N. L.; Braude, J. P.; Mitchell, T. W.; Coster, A. C.; Don, A. S.; Cooney, G. J.; Schmitz-Peiffer, C.; Turner, N.;
BBA-MOL BASIS DIS 1861 (11) :1828-1839, 2016