Publications

45 items matching your search terms.

Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

Murphy, K. J.; Reed, D. A.; Vennin, C.; Conway, J. R. W.; Nobis, M.; Yin, J. X.; Chambers, C. R.; Pereira, B. A.; Lee, V.; Filipe, E. C.; Trpceski, M.; Ritchie, S.; Lucas, M. C.; Warren, S. C.; Skhinas, J. N.; Magenau, A.; Metcalf, X. L.; Stoehr, J.; Major, G.; Parkin, A.; Bidanel, R.; Lyons, R. J.; Zaratzian, A.; Tayao, M.; Da Silva, A.; Abdulkhalek, L.; Australian Pancreatic Genome, Initiative; Australian Pancreatic Cancer Matrix, Atlas; Gill, A. J.; Johns, A. L.; Biankin, A. V.; Samra, J.; Grimmond, S. M.; Chou, A.; Goetz, J. G.; Samuel, M. S.; Lyons, J. G.; Burgess, A.; Caldon, C. E.; Horvath, L. G.; Daly, R. J.; Gadegaard, N.; Wang, Y.; Sansom, O. J.; Morton, J. P.; Cox, T. R.; Pajic, M.; Herrmann, D.; Timpson, P.

Science Advances 7 (40) :eabh0363, 2021 10.1126/sciadv.abh0363

Pirfenidone Reduces Epithelial-Mesenchymal Transition and Spheroid Formation in Breast Carcinoma through Targeting Cancer-Associated Fibroblasts (CAFs)

Es, H. A.; Cox, T. R.; Sarafraz-Yazdi, E.; Thiery, J. P.; Warkiani, M. E.

Cancers (Basel) 13 (20) :5118, 2021 10.3390/cancers13205118

Towards engineering heart tissues from bioprinted cardiac spheroids

Polonchuk, L.; Surija, L.; Lee, M. H.; Sharma, P.; Liu Chung Ming, C.; Richter, F.; Ben-Sefer, E.; Rad, M. A.; Mahmodi Sheikh Sarmast, H.; Shamery, W. A.; Tran, H. A.; Vettori, L.; Haeusermann, F.; Filipe, E. C.; Rnjak-Kovacina, J.; Cox, T.; Tipper, J.; Kabakova, I.; Gentile, C.

Biofabrication 13 (4) 2021 10.1088/1758-5090/ac14ca

Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition

Sharbeen, G.; McCarroll, J. A.; Akerman, A.; Kopecky, C.; Youkhana, J.; Kokkinos, J.; Holst, J.; Boyer, C.; Erkan, M.; Goldstein, D.; Timpson, P.; Cox, T. R.; Pereira, B. A.; Chitty, J. L.; Fey, S. K.; Najumudeen, A. K.; Campbell, A. D.; Sansom, O. J.; Ignacio, R. M. C.; Naim, S.; Liu, J.; Russia, N.; Lee, J.; Chou, A.; Johns, A.; Gill, A. J.; Gonzales-Aloy, E.; Gebski, V.; Guan, Y. F.; Pajic, M.; Turner, N.; Apte, M. V.; Davis, T. P.; Morton, J. P.; Haghighi, K. S.; Kasparian, J.; McLean, B. J.; Setargew, Y. F.; Phillips, P. A.; Australian Pancreatic Cancer Genome, Initiative

CANCER RESEARCH 81 (13) :3461-3479, 2021 10.1158/0008-5472.CAN-20-2496

Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP

Guo, G.; Papanicolaou, M.; Demarais, N. J.; Wang, Z.; Schey, K. L.; Timpson, P.; Cox, T. R.; Grey, A. C.

Nature Communications 12 (1) :3241, 2021 10.1038/s41467-021-23461-w

The matrix in cancer

Cox, T. R.

NATURE REVIEWS CANCER 21 (4) :217-238, 2021 10.1038/s41568-020-00329-7

Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype

Valdes-Mora, F.; Salomon, R.; Gloss, B. S.; Law, A. M. K.; Venhuizen, J.; Castillo, L.; Murphy, K. J.; Magenau, A.; Papanicolaou, M.; Rodriguez de la Fuente, L.; Roden, D. L.; Colino-Sanguino, Y.; Kikhtyak, Z.; Farbehi, N.; Conway, J. R. W.; Sikta, N.; Oakes, S. R.; Cox, T. R.; O'Donoghue, S. I.; Timpson, P.; Ormandy, C. J.; Gallego-Ortega, D.

Cell Reports 35 (2) :108945, 2021 10.1016/j.celrep.2021.108945

In Vitro 3D Models of Tunable Stiffness

Filipe, E. C.; Parker, A. L.; Cadell, A. L.; Major, G.; Croucher, D. R.; Cox, T. R.

Methods in Molecular Biology 2294 :27-42, 2021 10.1007/978-1-0716-1350-4_3

Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours

Setargew, Y. F. I.; Wyllie, K.; Grant, R. D.; Chitty, J. L.; Cox, T. R.

Cancers 13 (3) 2021 10.3390/cancers13030491

Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB

Holliday, H.; Roden, D.; Junankar, S.; Wu, S. Z.; Baker, L. A.; Krisp, C.; Chan, C. L.; McFarland, A.; Skhinas, J. N.; Cox, T. R.; Pal, B.; Huntington, N. D.; Ormandy, C. J.; Carroll, J. S.; Visvader, J.; Molloy, M. P.; Swarbrick, A.

iScience 24 (2) :102072, 2021 10.1016/j.isci.2021.102072

Stromal cell diversity associated with immune evasion in human triple-negative breast cancer

Wu, S. Z.; Roden, D. L.; Wang, C.; Holliday, H.; Harvey, K.; Cazet, A. S.; Murphy, K. J.; Pereira, B.; Al-Eryani, G.; Bartonicek, N.; Hou, R.; Torpy, J. R.; Junankar, S.; Chan, C. L.; Lam, C. E.; Hui, M. N.; Gluch, L.; Beith, J.; Parker, A.; Robbins, E.; Segara, D.; Mak, C.; Cooper, C.; Warrier, S.; Forrest, A.; Powell, J.; O'Toole, S.; Cox, T. R.; Timpson, P.; Lim, E.; Liu, X. S.; Swarbrick, A.

EMBO JOURNAL 1 (39) :e104063, 2020 10.15252/embj.2019104063

The Role of the ECM in Lung Cancer Dormancy and Outgrowth

Parker, A. L.; Cox, T. R.

Frontiers in Oncology 10 :1766, 2020 10.3389/fonc.2020.01766

Plasma polymerized nanoparticles effectively deliver dual siRNA and drug therapy in vivo

Michael, P.; Lam, Y. T.; Filipe, E. C.; Tan, R. P.; Chan, A. H. P.; Lee, B. S. L.; Feng, N.; Hung, J.; Cox, T. R.; Santos, M.; Wise, S. G.

Scientific Reports 10 (1) :12836, 2020 10.1038/s41598-020-69591-x

Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse

Nobis, M.; Herrmann, D.; Warren, S. C.; Strathdee, D.; Cox, T. R.; Anderson, K. I.; Timpson, P.

Small GTPases 11 (4) :240-247, 2020 10.1080/21541248.2018.1438024

The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development

Chitty, J. L.; Skhinas, J. N.; Filipe, E. C.; Wang, S.; Cupello, C. R.; Grant, R. D.; Yam, M.; Papanicolaou, M.; Major, G.; Zaratzian, A.; Da Silva, A. M.; Tayao, M.; Vennin, C.; Timpson, P.; Madsen, C. D.; Cox, T. R.

Cancer Reports 3 (1) :e1209, 2020 10.1002/cnr2.1209

The role of the extracellular matrix and the heparan sulfate proteoglycan Perlecan

Elgundi, Z.; Papanicolaou, M.; Major, G.; Cox, T. R.; Melrose, J.; Whitelock, J. M.; Farrugia, B. L.

Frontiers in Oncology 9 :1482, 2020 10.3389/fonc.2019.01482