Publications

40 items matching your search terms.

Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages

Munoz, M. A.; Fletcher, E. K.; Skinner, O. P.; Jurczyluk, J.; Kristianto, E.; Hodson, M. P.; Sun, S.; Ebetino, F. H.; Croucher, D. R.; Hansbro, P. M.; Center, J. R.; Rogers, M. J.

eLife 10 :e72430, 2021 10.7554/eLife.72430

Relationship between Circulating Lipids and Cytokines in Metastatic Castration-Resistant Prostate Cancer

Lin, H. M.; Yeung, N.; Hastings, J. F.; Croucher, D. R.; Huynh, K.; Meikle, T. G.; Mellett, N. A.; Kwan, E. M.; Davis, I. D.; Tran, B.; Mahon, K. L.; Zhang, A.; Stockler, M. R.; Briscoe, K.; Marx, G.; Bastick, P.; Crumbaker, M. L.; Joshua, A. M.; Azad, A. A.; Meikle, P. J.; Horvath, L. G.

Cancers 13 (19) :4964, 2021 10.3390/cancers13194964

Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging

Floerchinger, A.; Murphy, K. J.; Latham, S. L.; Warren, S. C.; McCulloch, A. T.; Lee, Y. K.; Stoehr, J.; Melenec, P.; Guaman, C. S.; Metcalf, X. L.; Lee, V.; Zaratzian, A.; Da Silva, A.; Tayao, M.; Rolo, S.; Phimmachanh, M.; Sultani, G.; McDonald, L.; Mason, S. M.; Ferrari, N.; Ooms, L. M.; Johnsson, A. E.; Spence, H. J.; Olson, M. F.; Machesky, L. M.; Sansom, O. J.; Morton, J. P.; Mitchell, C. A.; Samuel, M. S.; Croucher, D. R.; Welch, H. C. E.; Blyth, K.; Caldon, C. E.; Herrmann, D.; Anderson, K. I.; Timpson, P.; Nobis, M.

Cell Reports 36 (11) :109689, 2021 10.1016/j.celrep.2021.109689

Personalized Medicine for Neuroblastoma: Moving from Static Genotypes to Dynamic Simulations of Drug Response

Han, J. Z. R.; Hastings, J. F.; Phimmachanh, M.; Fey, D.; Kolch, W.; Croucher, D. R.

Journal of Personalized Medicine 11 (5) 2021 10.3390/jpm11050395

A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma

Gonzalez Rajal, A.; Marzec, K. A.; McCloy, R. A.; Nobis, M.; Chin, V.; Hastings, J. F.; Lai, K.; Kennerson, M.; Hughes, W. E.; Vaghjiani, V.; Timpson, P.; Cain, J. E.; Watkins, D. N.; Croucher, D. R.; Burgess, A.

eLife 10 2021 10.7554/eLife.65234

In Vitro 3D Models of Tunable Stiffness

Filipe, E. C.; Parker, A. L.; Cadell, A. L.; Major, G.; Croucher, D. R.; Cox, T. R.

Methods in Molecular Biology 2294 :27-42, 2021 10.1007/978-1-0716-1350-4_3

A zebrafish functional genomics model to investigate the role of human A20 variants in vivo

Cultrone, D.; Zammit, N. W.; Self, E.; Postert, B.; Han, J. Z. R.; Bailey, J.; Warren, J.; Croucher, D. R.; Kikuchi, K.; Bogdanovic, O.; Chtanova, T.; Hesselson, D.; Grey, S. T.

Scientific Reports 10 (1) :19085, 2020 10.1038/s41598-020-75917-6.

Histone deacetylases and histone deacetylase inhibitors in neuroblastoma

Phimmachanh, M.; Han, J. Z. R.; O'Donnell, Y. E. I.; Latham, S. L.; Croucher, D. R.

Front Cell Dev Biol 8 :578770, 2020 10.3389/fcell.2020.578770

A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers

Filipcik, P.; Latham, S. L.; Cadell, A. L.; Day, C. L.; Croucher, D. R.; Mace, P. D.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (35) :21308-21318, 2020 10.1073/pnas.2006429117

Myosin-18B regulates higher-order organization of the cardiac sarcomere through thin filament cross-linking and thick filament dynamics

Latham, S. L.; Weiss, N.; Schwanke, K.; Thiel, C.; Croucher, D. R.; Zweigerdt, R.; Manstein, D. J.; Taft, M. H.

Cell Reports 32 (9) :108090, 2020 10.1016/j.celrep.2020.108090

Applications of personalised signalling network models in precision oncology

Hastings, J. F.; O'Donnell, Y. E. I.; Fey, D.; Croucher, D. R.

PHARMACOLOGY & THERAPEUTICS 212 :107555, 2020 10.1016/j.pharmthera.2020.107555

Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

Hastings, J. F.; Gonzalez Rajal, A.; Latham, S. L.; Han, J. Z.; McCloy, R. A.; O'Donnell, Y. E.; Phimmachanh, M.; Murphy, A. D.; Nagrial, A.; Daneshvar, D.; Chin, V.; Watkins, D. N.; Burgess, A.; Croucher, D. R.

eLife 9 :e53367, 2020 10.7554/eLife.53367

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

Cipponi, A.; Goode, D. L.; Bedo, J.; McCabe, M. J.; Pajic, M.; Croucher, D. R.; Rajal, A. G.; Junankar, S. R.; Saunders, D. N.; Lobachevsky, P.; Papenfuss, A. T.; Nessem, D.; Nobis, M.; Warren, S. C.; Timpson, P.; Cowley, M.; Vargas, A. C.; Qiu, M. R.; Generali, D. G.; Keerthikumar, S.; Nguyen, U.; Corcoran, N. M.; Long, G. V.; Blay, J. Y.; Thomas, D. M.

SCIENCE 368 (6495) :1127-1131, 2020 10.1126/science.aau8768

Breathing New Life into the Mechanisms of Platinum Resistance in Lung Adenocarcinoma

Gonzalez-Rajal, A.; Hastings, J. F.; Watkins, D. N.; Croucher, D. R.; Burgess, A.

Frontiers in Cell and Developmental Biology 8 :305, 2020 10.3389/fcell.2020.00305

Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases

Trevelyan, S. J.; Brewster, J. L.; Burgess, A. E.; Crowther, J. M.; Cadell, A. L.; Parker, B. L.; Croucher, D. R.; Dobson, R. C. J.; Murphy, J. M.; Mace, P. D.

Science Signaling 13 (622) 2020 10.1126/scisignal.aay6318

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

Vennin, C.; Melenec, P.; Rouet, R.; Nobis, M.; Cazet, A. S.; Murphy, K. J.; Herrmann, D.; Reed, D. A.; Lucas, M. C.; Warren, S. C.; Elgundi, Z.; Pinese, M.; Kalna, G.; Roden, D.; Samuel, M.; Zaratzian, A.; Grey, S. T.; Da Silva, A.; Leung, W.; Mathivanan, S.; Wang, Y.; Braithwaite, A. W.; Christ, D.; Benda, A.; Parkin, A.; Phillips, P. A.; Whitelock, J. M.; Gill, A. J.; Sansom, O. J.; Croucher, D. R.; Parker, B. L.; Pajic, M.; Morton, J. P.; Cox, T. R.; Timpson, P.

Nature Communications 10 (1) :3637, 2019 10.1038/s41467-019-10968-6