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72 items matching your search terms.
TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation
Zammit, N. W.; McDowell, J.; Warren, J.; Muskovic, W.; Gamble, J.; Shi, Y. C.; Kaczorowski, D.; Chan, C. L.; Powell, J.; Ormandy, C.; Brown, D.; Oakes, S. R.; Grey, S. T.
Frontiers in Immunology 13 :811525, 2022 10.3389/fimmu.2022.811525
Selection of a novel AAV2/TNFAIP3 vector for local suppression of islet xenograft inflammation
Zammit, N. W.; Seeberger, K. L.; Zamerli, J.; Walters, S. N.; Lisowski, L.; Korbutt, G. S.; Grey, S. T.
XENOTRANSPLANTATION 28 (3) :e12669, 2021 10.1111/xen.12669
Selection of a novel AAV2/TNFAIP3 vector for local suppression of islet xenograft inflammation
Zammit, N. W.; Seeberger, K. L.; Zamerli, J.; Walters, S. N.; Lisowski, L.; Korbutt, G. S.; Grey, S. T.
XENOTRANSPLANTATION :e12669, 2020 10.1111/xen.12669
Spatial and Temporal Control of CRISPR-Cas9-Mediated Gene Editing Delivered via a Light-Triggered Liposome System
Aksoy, Y. A.; Yang, B.; Chen, W.; Hung, T.; Kuchel, R. P.; Zammit, N. W.; Grey, S. T.; Goldys, E. M.; Deng, W.
ACS Applied Materials & Interfaces 12 (47) :52433-52444, 2020 10.1021/acsami.0c16380
A zebrafish functional genomics model to investigate the role of human A20 variants in vivo
Cultrone, D.; Zammit, N. W.; Self, E.; Postert, B.; Han, J. Z. R.; Bailey, J.; Warren, J.; Croucher, D. R.; Kikuchi, K.; Bogdanovic, O.; Chtanova, T.; Hesselson, D.; Grey, S. T.
Scientific Reports 10 (1) :19085, 2020 10.1038/s41598-020-75917-6.
A20 as an immune tolerance factor can determine islet transplant outcomes
Zammit, N. W.; Walters, S. N.; Seeberger, K. L.; O'Connell, P. J.; Korbutt, G. S.; Grey, S. T.
Journal of Clinical Investigation Insight 4 (21) :e131028, 2019 10.1172/jci.insight.131028
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
Zammit, N. W.; Siggs, O. M.; Gray, P. E.; Horikawa, K.; Langley, D. B.; Walters, S. N.; Daley, S. R.; Loetsch, C.; Warren, J.; Yap, J. Y.; Cultrone, D.; Russell, A.; Malle, E. K.; Villanueva, J. E.; Cowley, M. J.; Gayevskiy, V.; Dinger, M. E.; Brink, R.; Zahra, D.; Chaudhri, G.; Karupiah, G.; Whittle, B.; Roots, C.; Bertram, E.; Yamada, M.; Jeelall, Y.; Enders, A.; Clifton, B. E.; Mabbitt, P. D.; Jackson, C. J.; Watson, S. R.; Jenne, C. N.; Lanier, L. L.; Wiltshire, T.; Spitzer, M. H.; Nolan, G. P.; Schmitz, F.; Aderem, A.; Porebski, B. T.; Buckle, A. M.; Abbott, D. W.; Ziegler, J. B.; Craig, M. E.; Benitez-Aguirre, P.; Teo, J.; Tangye, S. G.; King, C.; Wong, M.; Cox, M. P.; Phung, W.; Tang, J.; Sandoval, W.; Wertz, I. E.; Christ, D.; Goodnow, C. C.; Grey, S. T.
NATURE IMMUNOLOGY 20 (10) :1299-1310, 2019 10.1038/s41590-019-0492-0
OpenAccess publication CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
Vennin, C.; Melenec, P.; Rouet, R.; Nobis, M.; Cazet, A. S.; Murphy, K. J.; Herrmann, D.; Reed, D. A.; Lucas, M. C.; Warren, S. C.; Elgundi, Z.; Pinese, M.; Kalna, G.; Roden, D.; Samuel, M.; Zaratzian, A.; Grey, S. T.; Da Silva, A.; Leung, W.; Mathivanan, S.; Wang, Y.; Braithwaite, A. W.; Christ, D.; Benda, A.; Parkin, A.; Phillips, P. A.; Whitelock, J. M.; Gill, A. J.; Sansom, O. J.; Croucher, D. R.; Parker, B. L.; Pajic, M.; Morton, J. P.; Cox, T. R.; Timpson, P.
Nature Communications 10 (1) :3637, 2019 10.1038/s41467-019-10968-6
OpenAccess publication Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer
Chou, A.; Froio, D.; Nagrial, A. M.; Parkin, A.; Murphy, K. J.; Chin, V. T.; Wohl, D.; Steinmann, A.; Stark, R.; Drury, A.; Walters, S. N.; Vennin, C.; Burgess, A.; Pinese, M.; Chantrill, L. A.; Cowley, M. J.; Molloy, T. J.; Waddell, N.; Johns, A.; Grimmond, S. M.; Chang, D. K.; Biankin, A. V.; Sansom, O. J.; Morton, J. P.; Grey, S. T.; Cox, T. R.; Turchini, J.; Samra, J.; Clarke, S. J.; Timpson, P.; Gill, A. J.; Pajic, M.
GUT 67 (12) :2142-2155, 2018 10.1136/gutjnl-2017-315144
Oxygen-permeable microwell device maintains islet mass and integrity during shipping
Rojas-Canales, D. M.; Waibel, M.; Forget, A.; Penko, D.; Nitschke, J.; Harding, F. J.; Delalat, B.; Blencowe, A.; Loudovaris, T.; Grey, S. T.; Thomas, H. E.; Kay, T. W. H.; Drogemuller, C. J.; Voelcker, N. H.; Coates, P. T.
Endocrine Connections 7 (3) :490-503, 2018 10.1530/Ec-17-0349
Equipping the islet graft for self defence: targeting nuclear factor kappaB and implications for tolerance
Zammit, N. W.; Grey, S. T.
Current Opinion in Organ Transplantation 23 (1) :97-105, 2018 10.1097/MOT.0000000000000482
The 2017 Transplantation Awards: Recognizing a Landmark Clinical Trial and a Basic Science Discovery With Far-Reaching Implications
Grey, S. T.; Issa, F.
TRANSPLANTATION 101 (11) :2655-2656, 2017 10.1097/TP.0000000000001949
OpenAccess publication A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts
Nobis, M.; Herrmann, D.; Warren, S. C.; Kadir, S.; Leung, W.; Killen, M.; Magenau, A.; Stevenson, D.; Lucas, M. C.; Reischmann, N.; Vennin, C.; Conway, J. R. W.; Boulghourjian, A.; Zaratzian, A.; Law, A. M.; Gallego-Ortega, D.; Ormandy, C. J.; Walters, S. N.; Grey, S. T.; Bailey, J.; Chtanova, T.; Quinn, J. M. W.; Baldock, P. A.; Croucher, P. I.; Schwarz, J. P.; Mrowinska, A.; Zhang, L.; Herzog, H.; Masedunskas, A.; Hardeman, E. C.; Gunning, P. W.; Del Monte-Nieto, G.; Harvey, R. P.; Samuel, M. S.; Pajic, M.; McGhee, E. J.; Johnsson, A. E.; Sansom, O. J.; Welch, H. C. E.; Morton, J. P.; Strathdee, D.; Anderson, K. I.; Timpson, P.
Cell Reports 21 (1) :274-288, 2017 10.1016/j.celrep.2017.09.022
OpenAccess publication Inhibition of Y1 receptor signaling improves islet transplant outcome
Loh, K.; Shi, Y. C.; Walters, S.; Bensellam, M.; Lee, K.; Dezaki, K.; Nakata, M.; Ip, C. K.; Chan, J. Y.; Gurzov, E. N.; Thomas, H. E.; Waibel, M.; Cantley, J.; Kay, T. W.; Yada, T.; Laybutt, D. R.; Grey, S. T.; Herzog, H.
Nature Communications 8 (1) :490, 2017 10.1038/s41467-017-00624-2
Local Sphingosine Kinase 1 Activity Improves Islet Transplantation
Rojas-Canales, D.; Penko, D.; Myo Min, K. K.; Parham, K. A.; Peiris, H.; Haberberger, R. V.; Pitson, S. M.; Drogemuller, C.; Keating, D. J.; Grey, S. T.; Coates, P. T.; Bonder, C. S.; Jessup, C. F.
DIABETES 66 (5) :1301-1311, 2017 10.2337/db16-0837
MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD
Hsu, A. C.; Dua, K.; Starkey, M. R.; Haw, T. J.; Nair, P. M.; Nichol, K.; Zammit, N.; Grey, S. T.; Baines, K. J.; Foster, P. S.; Hansbro, P. M.; Wark, P. A.
Journal of Clinical Investigation Insight 2 (7) :e90443, 2017 10.1172/jci.insight.90443