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18 items matching your search terms.
A single-cell and spatially resolved atlas of human breast cancers
Wu, S. Z.; Al-Eryani, G.; Roden, D. L.; Junankar, S.; Harvey, K.; Andersson, A.; Thennavan, A.; Wang, C.; Torpy, J. R.; Bartonicek, N.; Wang, T.; Larsson, L.; Kaczorowski, D.; Weisenfeld, N. I.; Uytingco, C. R.; Chew, J. G.; Bent, Z. W.; Chan, C. L.; Gnanasambandapillai, V.; Dutertre, C. A.; Gluch, L.; Hui, M. N.; Beith, J.; Parker, A.; Robbins, E.; Segara, D.; Cooper, C.; Mak, C.; Chan, B.; Warrier, S.; Ginhoux, F.; Millar, E.; Powell, J. E.; Williams, S. R.; Liu, X. S.; O'Toole, S.; Lim, E.; Lundeberg, J.; Perou, C. M.; Swarbrick, A.
NATURE GENETICS 53 (9) :1334-1347, 2021 10.1038/s41588-021-00911-1
Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis
Wu, S. Z.; Roden, D. L.; Al-Eryani, G.; Bartonicek, N.; Harvey, K.; Cazet, A. S.; Chan, C. L.; Junankar, S.; Hui, M. N.; Millar, E. A.; Beretov, J.; Horvath, L.; Joshua, A. M.; Stricker, P.; Wilmott, J. S.; Quek, C.; Long, G. V.; Scolyer, R. A.; Yeung, B. Z.; Segara, D.; Mak, C.; Warrier, S.; Powell, J. E.; O'Toole, S.; Lim, E.; Swarbrick, A.
Genome Medicine 13 (1) :81, 2021 10.1186/s13073-021-00885-z
OpenAccess publication Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB
Holliday, H.; Roden, D.; Junankar, S.; Wu, S. Z.; Baker, L. A.; Krisp, C.; Chan, C. L.; McFarland, A.; Skhinas, J. N.; Cox, T. R.; Pal, B.; Huntington, N. D.; Ormandy, C. J.; Carroll, J. S.; Visvader, J.; Molloy, M. P.; Swarbrick, A.
iScience 24 (2) :102072, 2021 10.1016/j.isci.2021.102072
Stromal cell diversity associated with immune evasion in human triple-negative breast cancer
Wu, S. Z.; Roden, D. L.; Wang, C.; Holliday, H.; Harvey, K.; Cazet, A. S.; Murphy, K. J.; Pereira, B.; Al-Eryani, G.; Bartonicek, N.; Hou, R.; Torpy, J. R.; Junankar, S.; Chan, C. L.; Lam, C. E.; Hui, M. N.; Gluch, L.; Beith, J.; Parker, A.; Robbins, E.; Segara, D.; Mak, C.; Cooper, C.; Warrier, S.; Forrest, A.; Powell, J.; O'Toole, S.; Cox, T. R.; Timpson, P.; Lim, E.; Liu, X. S.; Swarbrick, A.
EMBO JOURNAL 1 (39) :e104063, 2020 10.15252/embj.2019104063
Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1
Teo, W. S.; Holliday, H.; Karthikeyan, N.; Cazet, A. S.; Roden, D. L.; Harvey, K.; Konrad, C. V.; Murali, R.; Varghese, B. A.; Thankamony, A. P.; Chan, C. L.; McFarland, A.; Junankar, S.; Ye, S.; Yang, J.; Nikolic, I.; Shah, J. S.; Baker, L. A.; Millar, E. K. A.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Kaplan, W.; Mellick, A. S.; O'Toole, S. A.; Swarbrick, A.; Nair, R.
Frontiers in Cell and Developmental Biology 8 :552, 2020 10.3389/fcell.2020.00552
OpenAccess publication Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer
Baker, L. A.; Holliday, H.; Roden, D.; Krisp, C.; Wu, S. Z.; Junankar, S.; Serandour, A. A.; Mohammed, H.; Nair, R.; Sankaranarayanan, G.; Law, A. M. K.; McFarland, A.; Simpson, P. T.; Lakhani, S.; Dodson, E.; Selinger, C.; Anderson, L.; Samimi, G.; Hacker, N. F.; Lim, E.; Ormandy, C. J.; Naylor, M. J.; Simpson, K.; Nikolic, I.; O'Toole, S.; Kaplan, W.; Cowley, M. J.; Carroll, J. S.; Molloy, M.; Swarbrick, A.
BREAST CANCER RES 22 (1) :63, 2020 10.1186/s13058-020-01306-6
MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer
Cipponi, A.; Goode, D. L.; Bedo, J.; McCabe, M. J.; Pajic, M.; Croucher, D. R.; Rajal, A. G.; Junankar, S. R.; Saunders, D. N.; Lobachevsky, P.; Papenfuss, A. T.; Nessem, D.; Nobis, M.; Warren, S. C.; Timpson, P.; Cowley, M.; Vargas, A. C.; Qiu, M. R.; Generali, D. G.; Keerthikumar, S.; Nguyen, U.; Corcoran, N. M.; Long, G. V.; Blay, J. Y.; Thomas, D. M.
SCIENCE 368 (6495) :1127-1131, 2020 10.1126/science.aau8768
OpenAccess publication High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes
Singh, M.; Al-Eryani, G.; Carswell, S.; Ferguson, J. M.; Blackburn, J.; Barton, K.; Roden, D.; Luciani, F.; Giang Phan, T.; Junankar, S.; Jackson, K.; Goodnow, C. C.; Smith, M. A.; Swarbrick, A.
Nature Communications 10 (1) :3120, 2019 10.1038/s41467-019-11049-4
OpenAccess publication Epigenomics of mammary gland development
Holliday, H.; Baker, L. A.; Junankar, S. R.; Clark, S. J.; Swarbrick, A.
BREAST CANCER RESEARCH 20 (1) :100, 2018 10.1186/s13058-018-1031-x
OpenAccess publication A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation
Oakes, S. R.; Gallego-Ortega, D.; Stanford, P. M.; Junankar, S.; Au, W. W. Y.; Kikhtyak, Z.; von Korff, A.; Sergio, C. M.; Law, A. M. K.; Castillo, L. E.; Allerdice, S. L.; Young, A. I. J.; Piggin, C.; Whittle, B.; Bertram, E.; Naylor, M. J.; Roden, D. L.; Donovan, J.; Korennykh, A.; Goodnow, C. C.; O'Bryan, M. K.; Ormandy, C. J.
PLoS Genetics 13 (11) :e1007072, 2017 10.1371/journal.pgen.1007072
OpenAccess publication ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype
Junankar, S.; Baker, L. A.; Roden, D. L.; Nair, R.; Elsworth, B.; Gallego-Ortega, D.; Lacaze, P.; Cazet, A.; Nikolic, I.; Teo, W. S.; Yang, J.; McFarland, A.; Harvey, K.; Naylor, M. J.; Lakhani, S. R.; Simpson, P. T.; Raghavendra, A.; Saunus, J.; Madore, J.; Kaplan, W.; Ormandy, C.; Millar, E. K.; O'Toole, S.; Yun, K.; Swarbrick, A.;
Nature Communications 6 :6548, 2015
OpenAccess publication Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer
Junankar, S.; Shay, G.; Jurczyluk, J.; Ali, N.; Down, J.; Pocock, N.; Parker, A.; Nguyen, A.; Sun, S.; Kashemirov, B.; Mckenna, C.E.; Croucher, P.I.; Swarbrick, A.; Weilbaecher, K.; Phan, T.G.; Rogers, M.J.
Cancer Discovery 5 :35-42, 2015
OpenAccess publication c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer
Nair, R. ; Roden, D. L. ; Teo, W. S. ; McFarland, A. ; Junankar, S. ; Ye, S. ; Nguyen, A. ; Yang, J. ; Nikolic, I. ; Hui, M. ; Morey, A. ; Shah, J. ; Pfefferle, A. D. ; Usary, J. ; Selinger, C. ; Baker, L. A. ; Armstrong, N. ; Cowley, M. J. ; Naylor, M. J. ; Ormandy, C. J. ; Lakhani, S. R. ; Herschkowitz, J. I. ; Perou, C. M. ; Kaplan, W. ; O'Toole, S. A. ; Swarbrick, A
ONCOGENE 33 (30) :3992-4002, 2014
OpenAccess publication Could the properties of IL-27 make it an ideal adjuvant for anticancer immunotherapy?
Swarbrick, A.; Junankar, S. R.; Batten, M.;
Oncoimmunology 2 (8) :e25409, 2013
OpenAccess publication Interleukin-27 signaling promotes immunity against endogenously arising murine tumors
Natividad, K. D.: Junankar, S. R.: Mohd Redzwan, N.: Nair, R.: Wirasinha, R. C.: King, C.: Brink, R.: Swarbrick, A.: Batten, M.:
PLoS One 8 (3) :e57469, 2013 10.1371/journal.pone.0057469
OpenAccess publication Redefining the expression and function of the inhibitor of differentiation 1 in mammary gland development
Nair, R.; Junankar, S.; O'Toole, S.; Shah, J.; McFarland, A.; Borovsky, A.; Bishop, M.J.; Swarbrick, A.
PLoS One 5 (8) :e11947, 2010 10.1371/journal.pone.0011947