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35 items matching your search terms.
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
McDonald, M. M.; Khoo, W. H.; Ng, P. Y.; Xiao, Y.; Zamerli, J.; Thatcher, P.; Kyaw, W.; Pathmanandavel, K.; Grootveld, A. K.; Moran, I.; Butt, D.; Nguyen, A.; Corr, A.; Warren, S.; Biro, M.; Butterfield, N. C.; Guilfoyle, S. E.; Komla-Ebri, D.; Dack, M. R. G.; Dewhurst, H. F.; Logan, J. G.; Li, Y.; Mohanty, S. T.; Byrne, N.; Terry, R. L.; Simic, M. K.; Chai, R.; Quinn, J. M. W.; Youlten, S. E.; Pettitt, J. A.; Abi-Hanna, D.; Jain, R.; Weninger, W.; Lundberg, M.; Sun, S.; Ebetino, F. H.; Timpson, P.; Lee, W. M.; Baldock, P. A.; Rogers, M. J.; Brink, R.; Williams, G. R.; Bassett, J. H. D.; Kemp, J. P.; Pavlos, N. J.; Croucher, P. I.; Phan, T. G.
CELL 184 (5) :1330-1347 e13, 2021 10.1016/j.cell.2021.02.002
Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone
Owen, K. L.; Gearing, L. J.; Zanker, D. J.; Brockwell, N. K.; Khoo, W. H.; Roden, D. L.; Cmero, M.; Mangiola, S.; Hong, M. K.; Spurling, A. J.; McDonald, M.; Chan, C. L.; Pasam, A.; Lyons, R. J.; Duivenvoorden, H. M.; Ryan, A.; Butler, L. M.; Mariadason, J. M.; Giang Phan, T.; Hayes, V. M.; Sandhu, S.; Swarbrick, A.; Corcoran, N. M.; Hertzog, P. J.; Croucher, P. I.; Hovens, C.; Parker, B. S.
EMBO REPORTS 21 (6) :e50162, 2020 10.15252/embr.202050162
Elevated Bone Hardness Under Denosumab Treatment, With Persisting Lower Osteocyte Viability During Discontinuation
Jahn-Rickert, K.; Wolfel, E. M.; Jobke, B.; Riedel, C.; Hellmich, M.; Werner, M.; McDonald, M. M.; Busse, B.
Frontiers in Endocrinology 11 :250, 2020 10.3389/fendo.2020.00250
Cancer Cell Dormancy in Metastasis
Summers, M. A.; McDonald, M. M.; Croucher, P. I.
Cold Spring Harbor Perspectives in Medicine 10 (4) 2020 10.1101/cshperspect.a037556
Pretreatment with Pamidronate Decreases Bone Formation but Increases Callus Bone Volume in a Rat Closed Fracture Model
Morse, A.; McDonald, M. M.; Mikulec, K.; Schindeler, A.; Munns, C. F.; Little, D. G.
CALCIFIED TISSUE INTERNATIONAL 106 (2) :172-179, 2020 10.1007/s00223-019-00615-z
Increased anabolic bone response in Dkk1 KO mice following tibial compressive loading
Morse, A.; Ko, F.; McDonald, M. M.; Lee, L.; Schindeler, A.; van der Meulen, M. C. H.; Little, D. G.
BONE 131 :115054, 2020 10.1016/j.bone.2019.115054
Loss of the Vitamin D Receptor in Human Breast Cancer Cells Promotes Epithelial to Mesenchymal Cell Transition and Skeletal Colonization
Horas, K.; Zheng, Y.; Fong-Yee, C.; Macfarlane, E.; Manibo, J.; Chen, Y.; Qiao, J.; Gao, M.; Haydar, N.; McDonald, M. M.; Croucher, P. I.; Zhou, H.; Seibel, M. J.
JOURNAL OF BONE AND MINERAL RESEARCH 34 (9) :1721-1732, 2019 10.1002/jbmr.3744
A Niche-Dependent Myeloid Transcriptome Signature Defines Dormant Myeloma Cells
Khoo, W. H.; Ledergor, G.; Weiner, A.; Roden, D. L.; Terry, R. L.; McDonald, M. M.; Chai, R. C.; De Veirman, K.; Owen, K. L.; Opperman, K. S.; Vandyke, K.; Clark, J. R.; Seckinger, A.; Kovacic, N.; Nguyen, A.; Mohanty, S. T.; Pettitt, J. A.; Xiao, Y.; Corr, A. P.; Seeliger, C.; Novotny, M.; Lasken, R. S.; Nguyen, T. V.; Oyajobi, B. O.; Aftab, D.; Swarbrick, A.; Parker, B.; Hewett, D. R.; Hose, D.; Vanderkerken, K.; Zannettino, A. C. W.; Amit, I.; Phan, T. G.; Croucher, P. I.
Blood 134 (1) :30-43, 2019 10.1182/blood.2018880930
Tumor Cell Dormancy and Reactivation in Bone: Skeletal Biology and Therapeutic Opportunities
Byrne, N.M., Summers, M.A. and McDonald, M.M.
JOURNAL OF BONE AND MINERAL RESEARCH PLUS 3 (3) :e10125, 2019 10.1002/jbm4.10125
Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume
Morse, A.; Cheng, T. L.; Schindeler, A.; McDonald, M. M.; Mohanty, S. T.; Kneissel, M.; Kramer, I.; Little, D. G.
CALCIFIED TISSUE INTERNATIONAL 103 (3) :298-310, 2018 10.1007/s00223-018-0420-6
Sclerostin antibody enhances bone formation in a rat model of distraction osteogenesis
McDonald, M. M.; Morse, A.; Birke, O.; Yu, N. Y. C.; Mikulec, K.; Peacock, L.; Schindeler, A.; Liu, M.; Ke, H. Z.; Little, D. G.
JOURNAL OF ORTHOPAEDIC RESEARCH 36 (4) :1106-1113, 2018 10.1002/jor.23726
Sclerostin Antibody Augments the Anabolic Bone Formation Response in a Mouse Model of Mechanical Tibial Loading
Morse, A.; Schindeler, A.; McDonald, M. M.; Kneissel, M.; Kramer, I.; Little, D. G.
JOURNAL OF BONE AND MINERAL RESEARCH 33 (3) :486-498, 2018 10.1002/jbmr.3330
Tumor Cell Dormancy—a Hallmark of Metastatic Growth and Disease Recurrence in Bone
Haydar, N.; McDonald, M.M.
Current Molecular Biology Reports 4 (2) :50-58, 2018
The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis
Fairfield H, Falank C, Harris E, Demambro V, McDonald M, Pettitt JA, Mohanty ST, Croucher P, Kramer I, Kneissel M, Rosen CJ, Reagan MR.
JOURNAL OF CELLULAR PHYSIOLOGY 233 (2) :1156-1167, 2018 10.1002/jcp.25976
Homozygous Dkk1 Knockout Mice Exhibit High Bone Mass Phenotype Due to Increased Bone Formation
McDonald, M. M.; Morse, A.; Schindeler, A.; Mikulec, K.; Peacock, L.; Cheng, T.; Bobyn, J.; Lee, L.; Baldock, P. A.; Croucher, P. I.; Tam, P. P. L.; Little, D. G.
CALCIFIED TISSUE INTERNATIONAL 102 (1) :105-116, 2018 10.1007/s00223-017-0338-4