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14 items matching your search terms.
Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages
Munoz, M. A.; Fletcher, E. K.; Skinner, O. P.; Jurczyluk, J.; Kristianto, E.; Hodson, M. P.; Sun, S.; Ebetino, F. H.; Croucher, D. R.; Hansbro, P. M.; Center, J. R.; Rogers, M. J.
eLife 10 :e72430, 2021 10.7554/eLife.72430
Molecular mechanisms of action of bisphosphonates and new insights into their effects outside the skeleton
Rogers, M. J.; Monkkonen, J.; Munoz, M. A.
BONE 139 :115493, 2020 10.1016/j.bone.2020.115493
OpenAccess publication Defective Protein Prenylation in a Spectrum of Patients With Mevalonate Kinase Deficiency
Munoz, M. A.; Jurczyluk, J.; Simon, A.; Hissaria, P.; Arts, R. J. W.; Coman, D.; Boros, C.; Mehr, S.; Rogers, M. J.
Frontiers in Immunology 10 :1900, 2019 10.3389/fimmu.2019.01900
Lack of protein prenylation promotes NLRP3 inflammasome assembly in human monocytes
Skinner, O. P.; Jurczyluk, J.; Baker, P. J.; Masters, S. L.; Rios Wilks, A. G.; Clearwater, M. S.; Robertson, A. A. B.; Schroder, K.; Mehr, S.; Munoz, M. A.; Rogers, M. J.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 143 (6) :2315-2317 e3, 2019 10.1016/j.jaci.2019.02.013
From vesicle to cytosol
Rogers, M. J.; Munoz, M. A.
eLife 7 :e38847, 2018 10.7554/eLife.38847
OpenAccess publication Defective protein prenylation is a diagnostic biomarker of mevalonate kinase deficiency
Munoz, M. A.; Jurczyluk, J.; Mehr, S.; Chai, R. C.; Arts, R. J. W.; Sheu, A.; McMahon, C.; Center, J. R.; Singh-Grewal, D.; Chaitow, J.; Campbell, D. E.; Quinn, J. M. W.; Alexandrov, K.; Tnimov, Z.; Tangye, S. G.; Simon, A.; Phan, T. G.; Rogers, M. J.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 140 (3) :873-875.e6, 2017 10.1016/j.jaci.2017.02.033
OpenAccess publication A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton
Ali, N. ; Jurczyluk, J. ; Shay, G. ; Tnimov, Z. ; Alexandrov, K. ; Munoz, M. A. ; Skinner, O. P. ; Pavlos, N. J. ; Rogers, M. J.;
Small GTPases 30 (4) :637-46, 2015
OpenAccess publication Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells
Mayor, R.; Munoz, M.; Coolen, M.W.; Custodio, J.; Esteller, M.; Clark, S.J.; Peinado, M.A.
Epigenetics 6 (9) :1138-1148, 2011
OpenAccess publication The E3 Ubiquitin Ligase EDD Regulates S-Phase and G(2)/M DNA Damage Checkpoints
Munoz, M. A.;Saunders, D. N.;Henderson, M. J.;Clancy, J. L.;Russell, A. J.;Lehrbach, G.;Musgrove, E. A.;Watts, C. K.;Sutherland, R. L. :
CELL CYCLE 6 (24) :3070-3077, 2007
OpenAccess publication EDD mediates DNA damage-induced activation of CHK2
Henderson, M. J.;Munoz, M. A.;Saunders, D. N.;Clancy, J. L.;Russell, A. J.;Williams, B.;Pappin, D.;Khanna, K. K.;Jackson, S. P.;Sutherland, R. L.;Watts, C. K. :
JOURNAL OF BIOLOGICAL CHEMISTRY 281 (52) :39990-40000, 2006
Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy
Frigola, J.;Munoz, M.;Clark, S. J.;Moreno, V.;Capella, G.;Peinado, M. A. :
ONCOGENE 24 (49) :7320-6, 2005
EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response
Henderson, M. J.;Russell, A. J.;Hird, S.;Munoz, M.;Clancy, J. L.;Lehrbach, G. M.;Calanni, S. T.;Jans, D. A.;Sutherland, R. L.;Watts, C. K. :
JOURNAL OF BIOLOGICAL CHEMISTRY 277 (29) :26468-78, 2002
Neuropeptide Y and the nonpeptide antagonist BIBP 3226 share an overlapping binding site at the human Y1 receptor
Sautel, M.;Rudolf, K.;Wittneben, H.;Herzog, H.;Martinez, R.;Munoz, M.;Eberlein, W.;Engel, W.;Walker, P.;Beck-Sickinger, A. G. :
MOLECULAR PHARMACOLOGY 50 (2) :285-92, 1996
High level expression of human neuropeptide Y receptors in mammalian cells infected with a recombinant vaccinia virus
Walker, P.;Munoz, M.;Combe, M. C.;Grouzmann, E.;Herzog, H.;Selbie, L.;Shine, J.;Brunner, H. R.;Waeber, B.;Wittek, R. :
MOLECULAR AND CELLULAR ENDOCRINOLOGY 91 (1-2) :107-12, 1993