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9 items matching your search terms.
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
Vennin, C.; Melenec, P.; Rouet, R.; Nobis, M.; Cazet, A. S.; Murphy, K. J.; Herrmann, D.; Reed, D. A.; Lucas, M. C.; Warren, S. C.; Elgundi, Z.; Pinese, M.; Kalna, G.; Roden, D.; Samuel, M.; Zaratzian, A.; Grey, S. T.; Da Silva, A.; Leung, W.; Mathivanan, S.; Wang, Y.; Braithwaite, A. W.; Christ, D.; Benda, A.; Parkin, A.; Phillips, P. A.; Whitelock, J. M.; Gill, A. J.; Sansom, O. J.; Croucher, D. R.; Parker, B. L.; Pajic, M.; Morton, J. P.; Cox, T. R.; Timpson, P.
Nature Communications 10 (1) :3637, 2019 10.1038/s41467-019-10968-6
OpenAccess publication Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer
Conway, J. R. W.; Warren, S. C.; Herrmann, D.; Murphy, K. J.; Cazet, A. S.; Vennin, C.; Shearer, R. F.; Killen, M. J.; Magenau, A.; Melenec, P.; Pinese, M.; Nobis, M.; Zaratzian, A.; Boulghourjian, A.; Da Silva, A. M.; Del Monte-Nieto, G.; Adam, A. S. A.; Harvey, R. P.; Haigh, J. J.; Wang, Y.; Croucher, D. R.; Sansom, O. J.; Pajic, M.; Caldon, C. E.; Morton, J. P.; Timpson, P.
Cell Reports 23 (11) :3312-3326, 2018 10.1016/j.celrep.2018.05.038
OpenAccess publication A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts
Nobis, M.; Herrmann, D.; Warren, S. C.; Kadir, S.; Leung, W.; Killen, M.; Magenau, A.; Stevenson, D.; Lucas, M. C.; Reischmann, N.; Vennin, C.; Conway, J. R. W.; Boulghourjian, A.; Zaratzian, A.; Law, A. M.; Gallego-Ortega, D.; Ormandy, C. J.; Walters, S. N.; Grey, S. T.; Bailey, J.; Chtanova, T.; Quinn, J. M. W.; Baldock, P. A.; Croucher, P. I.; Schwarz, J. P.; Mrowinska, A.; Zhang, L.; Herzog, H.; Masedunskas, A.; Hardeman, E. C.; Gunning, P. W.; Del Monte-Nieto, G.; Harvey, R. P.; Samuel, M. S.; Pajic, M.; McGhee, E. J.; Johnsson, A. E.; Sansom, O. J.; Welch, H. C. E.; Morton, J. P.; Strathdee, D.; Anderson, K. I.; Timpson, P.
Cell Reports 21 (1) :274-288, 2017 10.1016/j.celrep.2017.09.022
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
Vennin, C.; Chin, V. T.; Warren, S. C.; Lucas, M. C.; Herrmann, D.; Magenau, A.; Melenec, P.; Walters, S. N.; Del Monte-Nieto, G.; Conway, J. R.; Nobis, M.; Allam, A. H.; McCloy, R. A.; Currey, N.; Pinese, M.; Boulghourjian, A.; Zaratzian, A.; Adam, A. A.; Heu, C.; Nagrial, A. M.; Chou, A.; Steinmann, A.; Drury, A.; Froio, D.; Giry-Laterriere, M.; Harris, N. L.; Phan, T.; Jain, R.; Weninger, W.; McGhee, E. J.; Whan, R.; Johns, A. L.; Samra, J. S.; Chantrill, L.; Gill, A. J.; Kohonen-Corish, M.; Harvey, R. P.; Biankin, A. V.; Australian Pancreatic Cancer Genome, Initiative; Evans, T. R.; Anderson, K. I.; Grey, S. T.; Ormandy, C. J.; Gallego-Ortega, D.; Wang, Y.; Samuel, M. S.; Sansom, O. J.; Burgess, A.; Cox, T. R.; Morton, J. P.; Pajic, M.; Timpson, P.
Science Translational Medicine 9 :eaai8504, 2017 10.1126/scitranslmed.aai8504
OpenAccess publication Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease and drug-dependent dynamic regulation of cell-cell junctions in live tissue
Erami, Z.; Herrmann, D.; Warren, S.C.; Nobis, M.; McGhee, E.J.; Lucas, M.C.; Leung, W.; Reischmann, N.; Mrowinska, A.; Schwarz, J.P.; Kadir, S.; Conway, J.R.W.; Vennin, C.; Karim, S.A.; Campbell, A.D.; Gallego-Ortega, D.; Magenau, A.; Murphy, K.J.; Ridgway, R.A.; Law, A.M.; Walters, S.N.; Grey, S. T.; Croucher, D.R.; Zhang, L.; Herzog, H.; Hardeman, E. C.; Gunning, P.W.; Ormandy, C.J.; Evans, T.R.J.; Strathdee, D.; Sansom, O. J.; Morton, J. P.; Anderson, K.I.; Timpson, P.;
Cell Reports 14 (1) :152-67, 2016
OpenAccess publication The Rac-FRET mouse Reveals tight spatiotemporal control of Rac activity in primary cells and tissues
Johnsson, A. K.; Dai, Y.; Nobis, M.; Baker, M. J.; McGhee, E. J.; Walker, S.; Schwarz, J. P.; Kadir, S.; Morton, J. P.; Myant, K. B.; Huels, D. J.; Segonds-Pichon, A.; Sansom, O. J.; Anderson, K. I.; Timpson, P.; Welch, H. C.;
Cell Reports 6 (6) :1153-64, 2014
OpenAccess publication Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging
Nobis, M.; McGhee, E. J.; Herrmann, D.; Magenau, A.; Morton, J. P.; Anderson, K. I.; Timpson, P.;
Cell Adhesion & Migration 8 (5) :478-86, 2014
OpenAccess publication Advanced intravital subcellular imaging reveals vital three-dimensional signalling events driving cancer cell behaviour and drug responses in live tissue
Nobis, M.; Carragher, N. O.; McGhee, E. J.; Morton, J. P.; Sansom, O. J.; Anderson, K. I.; Timpson, P.;
FEBS Journal 280 (21) :5177-97, 2013
OpenAccess publication Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer
Nobis, M.; McGhee, E. J.; Morton, J. P.; Schwarz, J. P.; Karim, S. A.; Quinn, J.; Edward, M.; Campbell, A. D.; McGarry, L. C.; Evans, T. R.; Brunton, V. G.; Frame, M. C.; Carragher, N. O.; Wang, Y.; Sansom, O. J.; Timpson, P.; Anderson, K. I.;
CANCER RESEARCH 73 (15) :4674-86, 2013