Publications

96 items matching your search terms.

A single-cell and spatially resolved atlas of human breast cancers

Wu, S. Z.; Al-Eryani, G.; Roden, D. L.; Junankar, S.; Harvey, K.; Andersson, A.; Thennavan, A.; Wang, C.; Torpy, J. R.; Bartonicek, N.; Wang, T.; Larsson, L.; Kaczorowski, D.; Weisenfeld, N. I.; Uytingco, C. R.; Chew, J. G.; Bent, Z. W.; Chan, C. L.; Gnanasambandapillai, V.; Dutertre, C. A.; Gluch, L.; Hui, M. N.; Beith, J.; Parker, A.; Robbins, E.; Segara, D.; Cooper, C.; Mak, C.; Chan, B.; Warrier, S.; Ginhoux, F.; Millar, E.; Powell, J. E.; Williams, S. R.; Liu, X. S.; O'Toole, S.; Lim, E.; Lundeberg, J.; Perou, C. M.; Swarbrick, A.

NATURE GENETICS 53 (9) :1334-1347, 2021 10.1038/s41588-021-00911-1

SP142 PD-L1 Scoring Shows High Interobserver and Intraobserver Agreement in Triple-negative Breast Carcinoma But Overall Low Percentage Agreement With Other PD-L1 Clones SP263 and 22C3

Pang, J. B.; Castles, B.; Byrne, D. J.; Button, P.; Hendry, S.; Lakhani, S. R.; Sivasubramaniam, V.; Cooper, W. A.; Armes, J.; Millar, E. K. A.; Raymond, W.; Roberts-Thomson, S.; Kumar, B.; Burr, M.; Selinger, C.; Harvey, K.; Chan, C.; Beith, J.; Clouston, D.; O'Toole, S. A.; Fox, S. B.; kConFab

American Journal Of Surgical Pathology 45 (8) :1108-1117, 2021 10.1097/PAS.0000000000001701

Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis

Wu, S. Z.; Roden, D. L.; Al-Eryani, G.; Bartonicek, N.; Harvey, K.; Cazet, A. S.; Chan, C. L.; Junankar, S.; Hui, M. N.; Millar, E. A.; Beretov, J.; Horvath, L.; Joshua, A. M.; Stricker, P.; Wilmott, J. S.; Quek, C.; Long, G. V.; Scolyer, R. A.; Yeung, B. Z.; Segara, D.; Mak, C.; Warrier, S.; Powell, J. E.; O'Toole, S.; Lim, E.; Swarbrick, A.

Genome Medicine 13 (1) :81, 2021 10.1186/s13073-021-00885-z

Squamous metaplasia of lactiferous ducts (SMOLD): an under-recognised entity

Ofri, A.; Dona, E.; O'Toole, S.

BMJ Case Rep 13 (12) 2020 10.1136/bcr-2020-237568

Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1

Kalaw, E.; Lim, M.; Kutasovic, J. R.; Sokolova, A.; Taege, L.; Johnstone, K.; Bennett, J.; Saunus, J. M.; Niland, C.; Ferguson, K.; Gresshoff, I.; Bettington, M.; Pathmanathan, N.; Tse, G. M.; Papadimos, D.; Pathmanathan, R.; Harris, G.; Yamaguchi, R.; Tan, P. H.; Fox, S.; O'Toole, S. A.; Simpson, P. T.; Lakhani, S. R.; McCart Reed, A. E.

British Journal of Cancer 123 (11) :1665-1672, 2020 10.1038/s41416-020-01065-3

Stromal cell diversity associated with immune evasion in human triple-negative breast cancer

Wu, S. Z.; Roden, D. L.; Wang, C.; Holliday, H.; Harvey, K.; Cazet, A. S.; Murphy, K. J.; Pereira, B.; Al-Eryani, G.; Bartonicek, N.; Hou, R.; Torpy, J. R.; Junankar, S.; Chan, C. L.; Lam, C. E.; Hui, M. N.; Gluch, L.; Beith, J.; Parker, A.; Robbins, E.; Segara, D.; Mak, C.; Cooper, C.; Warrier, S.; Forrest, A.; Powell, J.; O'Toole, S.; Cox, T. R.; Timpson, P.; Lim, E.; Liu, X. S.; Swarbrick, A.

EMBO JOURNAL 1 (39) :e104063, 2020 10.15252/embj.2019104063

TILs Immunophenotype in Breast Cancer Predicts Local Failure and Overall Survival: Analysis in a Large Radiotherapy Trial with Long-Term Follow-Up

Millar, E.; Browne, L.; Slapetova, I.; Shang, F.; Ren, Y.; Bradshaw, R.; Ann Brauer, H.; O'Toole, S.; Beretov, J.; Whan, R.; Graham, P. H.

Cancers 12 (9) :2365, 2020 10.3390/cancers12092365

Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1

Teo, W. S.; Holliday, H.; Karthikeyan, N.; Cazet, A. S.; Roden, D. L.; Harvey, K.; Konrad, C. V.; Murali, R.; Varghese, B. A.; Thankamony, A. P.; Chan, C. L.; McFarland, A.; Junankar, S.; Ye, S.; Yang, J.; Nikolic, I.; Shah, J. S.; Baker, L. A.; Millar, E. K. A.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Kaplan, W.; Mellick, A. S.; O'Toole, S. A.; Swarbrick, A.; Nair, R.

Frontiers in Cell and Developmental Biology 8 :552, 2020 10.3389/fcell.2020.00552

Elevated levels of tumour apolipoprotein D independently predict poor outcome in breast cancer patients

Jankovic-Karasoulos, T.; Bianco-Miotto, T.; Butler, M. S.; Butler, L. M.; McNeil, C. M.; O'Toole, S. A.; Millar, E. K. A.; Sakko, A. J.; Ruiz, A. I.; Birrell, S. N.; Sutherland, R. L.; Hickey, T. E.; Tilley, W. D.; Ricciardelli, C.

HISTOPATHOLOGY 76 (7) :976-987, 2020 10.1111/his.14081

Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer

Baker, L. A.; Holliday, H.; Roden, D.; Krisp, C.; Wu, S. Z.; Junankar, S.; Serandour, A. A.; Mohammed, H.; Nair, R.; Sankaranarayanan, G.; Law, A. M. K.; McFarland, A.; Simpson, P. T.; Lakhani, S.; Dodson, E.; Selinger, C.; Anderson, L.; Samimi, G.; Hacker, N. F.; Lim, E.; Ormandy, C. J.; Naylor, M. J.; Simpson, K.; Nikolic, I.; O'Toole, S.; Kaplan, W.; Cowley, M. J.; Carroll, J. S.; Molloy, M.; Swarbrick, A.

BREAST CANCER RES 22 (1) :63, 2020 10.1186/s13058-020-01306-6

BRCA1 promoter methylation and clinical outcomes in ovarian cancer: an individual patient data meta-analysis

Kalachand, R. D.; Stordal, B.; Madden, S.; Chandler, B.; Cunningham, J.; Goode, E. L.; Ruscito, I.; Braicu, E. I.; Sehouli, J.; Ignatov, A.; Yu, H.; Katsaros, D.; Mills, G. B.; Lu, K. H.; Carey, M. S.; Timms, K. M.; Kupryjanczyk, J.; Rzepecka, I. K.; Podgorska, A.; McAlpine, J. N.; Swisher, E. M.; Bernards, S. S.; O'Riain, C.; O'Toole, S.; O'Leary, J. J.; Bowtell, D. D.; Thomas, D. M.; Prieske, K.; Joosse, S. A.; Woelber, L.; Chaudhry, P.; Hafner, N.; Runnebaum, I. B.; Hennessy, B. T.

JNCI-Journal of the National Cancer Institute 112 (12) :1190-1203, 2020 10.1093/jnci/djaa070

Clinical utility of in situ hybridization assays in head and neck neoplasms

Luk, P. P.; Selinger, C. I.; Cooper, W. A.; Mahar, A.; Palme, C. E.; O'Toole, S. A.; Clark, J. R.; Gupta, R.

Head and Neck Pathology 13 (3) :397-414, 2019 10.1007/s12105-018-0988-1

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis

Smith, H. W.; Hirukawa, A.; Sanguin-Gendreau, V.; Nandi, I.; Dufour, C. R.; Zuo, D.; Tandoc, K.; Leibovitch, M.; Singh, S.; Rennhack, J. P.; Swiatnicki, M.; Lavoie, C.; Papavasiliou, V.; Temps, C.; Carragher, N. O.; Unciti-Broceta, A.; Savage, P.; Basik, M.; van Hoef, V.; Larsson, O.; Cooper, C. L.; Vargas Calderon, A. C.; Beith, J.; Millar, E.; Selinger, C.; Giguere, V.; Park, M.; Harris, L. N.; Varadan, V.; Andrechek, E. R.; O'Toole, S. A.; Topisirovic, I.; Muller, W. J.

Nature Communications 10 (1) :2901, 2019 10.1038/s41467-019-10681-4

Diagnosis of fusion genes using targeted RNA sequencing

Heyer, E. E.; Deveson, I. W.; Wooi, D.; Selinger, C. I.; Lyons, R. J.; Hayes, V. M.; O'Toole, S. A.; Ballinger, M. L.; Gill, D.; Thomas, D. M.; Mercer, T. R.; Blackburn, J.

Nature Communications 10 (1) :1388, 2019 10.1038/s41467-019-09374-9

Optimise not compromise: The importance of a multidisciplinary breast cancer patient pathway in the era of oncoplastic and reconstructive surgery

Strach, M. C.; Prasanna, T.; Kirova, Y. M.; Alran, S.; O'Toole, S.; Beith, J. M.; Poortmans, P.; McNeil, C. M.; Carroll, S.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 134 :10-21, 2019 10.1016/j.critrevonc.2018.11.007

Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications

McCart Reed, A. E.; Kalaw, E.; Nones, K.; Bettington, M.; Lim, M.; Bennett, J.; Johnstone, K.; Kutasovic, J. R.; Saunus, J. M.; Kazakoff, S.; Xu, Q.; Wood, S.; Holmes, O.; Leonard, C.; Reid, L. E.; Black, D.; Niland, C.; Ferguson, K.; Gresshoff, I.; Raghavendra, A.; Harvey, K.; Cooper, C.; Liu, C.; Kalinowski, L.; Reid, A. S.; Davidson, M.; Pearson, J. V.; Pathmanathan, N.; Tse, G.; Papadimos, D.; Pathmanathan, R.; Harris, G.; Yamaguchi, R.; Tan, P. H.; Fox, S.; O'Toole, S. A.; Simpson, P. T.; Waddell, N.; Lakhani, S. R.

JOURNAL OF PATHOLOGY 247 (2) :214-227, 2019 10.1002/path.5184