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110 items matching your search terms.
Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer
Saunus, J. M.; De Luca, X. M.; Northwood, K.; Raghavendra, A.; Hasson, A.; McCart Reed, A. E.; Lim, M.; Lal, S.; Vargas, A. C.; Kutasovic, J. R.; Dalley, A. J.; Miranda, M.; Kalaw, E.; Kalita-de Croft, P.; Gresshoff, I.; Al-Ejeh, F.; Gee, J. M. W.; Ormandy, C.; Khanna, K. K.; Beesley, J.; Chenevix-Trench, G.; Green, A. R.; Rakha, E. A.; Ellis, I. O.; Nicolau, D. V., Jr.; Simpson, P. T.; Lakhani, S. R.
NPJ Breast Cancer 8 (1) :57, 2022 10.1038/s41523-022-00425-x
TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation
Zammit, N. W.; McDowell, J.; Warren, J.; Muskovic, W.; Gamble, J.; Shi, Y. C.; Kaczorowski, D.; Chan, C. L.; Powell, J.; Ormandy, C.; Brown, D.; Oakes, S. R.; Grey, S. T.
Frontiers in Immunology 13 :811525, 2022 10.3389/fimmu.2022.811525
NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers
Sun, Y.; Yang, N.; Utama, F. E.; Udhane, S. S.; Zhang, J.; Peck, A. R.; Yanac, A.; Duffey, K.; Langenheim, J. F.; Udhane, V.; Xia, G.; Peterson, J. F.; Jorns, J. M.; Nevalainen, M. T.; Rouet, R.; Schofield, P.; Christ, D.; Ormandy, C. J.; Rosenberg, A. L.; Chervoneva, I.; Tsaih, S. W.; Flister, M. J.; Fuchs, S. Y.; Wagner, K. U.; Rui, H.
Science Advances 7 (38) :eabc8145, 2021 10.1126/sciadv.abc8145
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype
Valdes-Mora, F.; Salomon, R.; Gloss, B. S.; Law, A. M. K.; Venhuizen, J.; Castillo, L.; Murphy, K. J.; Magenau, A.; Papanicolaou, M.; Rodriguez de la Fuente, L.; Roden, D. L.; Colino-Sanguino, Y.; Kikhtyak, Z.; Farbehi, N.; Conway, J. R. W.; Sikta, N.; Oakes, S. R.; Cox, T. R.; O'Donoghue, S. I.; Timpson, P.; Ormandy, C. J.; Gallego-Ortega, D.
Cell Reports 35 (2) :108945, 2021 10.1016/j.celrep.2021.108945
OpenAccess publication Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB
Holliday, H.; Roden, D.; Junankar, S.; Wu, S. Z.; Baker, L. A.; Krisp, C.; Chan, C. L.; McFarland, A.; Skhinas, J. N.; Cox, T. R.; Pal, B.; Huntington, N. D.; Ormandy, C. J.; Carroll, J. S.; Visvader, J.; Molloy, M. P.; Swarbrick, A.
iScience 24 (2) :102072, 2021 10.1016/j.isci.2021.102072
Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1
Teo, W. S.; Holliday, H.; Karthikeyan, N.; Cazet, A. S.; Roden, D. L.; Harvey, K.; Konrad, C. V.; Murali, R.; Varghese, B. A.; Thankamony, A. P.; Chan, C. L.; McFarland, A.; Junankar, S.; Ye, S.; Yang, J.; Nikolic, I.; Shah, J. S.; Baker, L. A.; Millar, E. K. A.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Kaplan, W.; Mellick, A. S.; O'Toole, S. A.; Swarbrick, A.; Nair, R.
Frontiers in Cell and Developmental Biology 8 :552, 2020 10.3389/fcell.2020.00552
OpenAccess publication Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer
Baker, L. A.; Holliday, H.; Roden, D.; Krisp, C.; Wu, S. Z.; Junankar, S.; Serandour, A. A.; Mohammed, H.; Nair, R.; Sankaranarayanan, G.; Law, A. M. K.; McFarland, A.; Simpson, P. T.; Lakhani, S.; Dodson, E.; Selinger, C.; Anderson, L.; Samimi, G.; Hacker, N. F.; Lim, E.; Ormandy, C. J.; Naylor, M. J.; Simpson, K.; Nikolic, I.; O'Toole, S.; Kaplan, W.; Cowley, M. J.; Carroll, J. S.; Molloy, M.; Swarbrick, A.
BREAST CANCER RES 22 (1) :63, 2020 10.1186/s13058-020-01306-6
MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma
Castillo, L.; Young, A. I. J.; Mawson, A.; Schafranek, P.; Steinmann, A. M.; Nessem, D.; Parkin, A.; Johns, A.; Chou, A.; Law, A. M. K.; Lucas, M. C.; Murphy, K. J.; Deng, N.; Gallego-Ortega, D.; Caldon, C. E.; Australian Pancreatic Cancer Genome, Initiative; Timpson, P.; Pajic, M.; Ormandy, C. J.; Oakes, S. R.
ONCOGENE 39 (8) :1821-1829, 2020 10.1038/s41388-019-1091-0
OpenAccess publication ELF5 modulates the estrogen receptor cistrome in breast cancer
Piggin, C. L.; Roden, D. L.; Law, A. M. K.; Molloy, M. P.; Krisp, C.; Swarbrick, A.; Naylor, M. J.; Kalyuga, M.; Kaplan, W.; Oakes, S. R.; Gallego-Ortega, D.; Clark, S. J.; Carroll, J. S.; Bartonicek, N.; Ormandy, C. J.
PLoS Genetics 16 (1) :e1008531, 2020 10.1371/journal.pgen.1008531
OpenAccess publication The proliferative and apoptotic landscape of basal-like breast cancer
Alexandrou, S.; George, S. M.; Ormandy, C. J.; Lim, E.; Oakes, S. R.; Caldon, C. E.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20 (3) :667, 2019 10.3390/ijms20030667
Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion
Young, A. I.; Timpson, P.; Gallego-Ortega, D.; Ormandy, C. J.; Oakes, S. R.
Cell Adhesion & Migration 12 (6) :513-523, 2018 10.1080/19336918.2017.1393591
OpenAccess publication Single-Cell Transcriptomics in Cancer Immunobiology: The Future of Precision Oncology
Valdes-Mora, F.; Handler, K.; Law, A. M. K.; Salomon, R.; Oakes, S. R.; Ormandy, C. J.; Gallego-Ortega, D.
Frontiers in Immunology 9 :2582, 2018 10.3389/fimmu.2018.02582
Static droplet array for culturing single live adherent cells in an isolated chemical microenvironment
Hassanzadeh-Barforoushi, A.; Law, A. M. K.; Hejri, A.; Asadnia, M.; Ormandy, C. J.; Gallego-Ortega, D.; Ebrahimi Warkiani, M.
LAB ON A CHIP 18 (15) :2156-2166, 2018 10.1039/c8lc00403j
OpenAccess publication Andy's Algorithms: new automated digital image analysis pipelines for FIJI
Law, A. M. K.; Yin, J. X. M.; Castillo, L.; Young, A. I. J.; Piggin, C.; Rogers, S.; Caldon, C. E.; Burgess, A.; Millar, E. K. A.; O'Toole, S. A.; Gallego-Ortega, D.; Ormandy, C. J.; Oakes, S. R.
Scientific Reports 7 (1) :15717, 2017 10.1038/s41598-017-15885-6
OpenAccess publication A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation
Oakes, S. R.; Gallego-Ortega, D.; Stanford, P. M.; Junankar, S.; Au, W. W. Y.; Kikhtyak, Z.; von Korff, A.; Sergio, C. M.; Law, A. M. K.; Castillo, L. E.; Allerdice, S. L.; Young, A. I. J.; Piggin, C.; Whittle, B.; Bertram, E.; Naylor, M. J.; Roden, D. L.; Donovan, J.; Korennykh, A.; Goodnow, C. C.; O'Bryan, M. K.; Ormandy, C. J.
PLoS Genetics 13 (11) :e1007072, 2017 10.1371/journal.pgen.1007072
OpenAccess publication A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts
Nobis, M.; Herrmann, D.; Warren, S. C.; Kadir, S.; Leung, W.; Killen, M.; Magenau, A.; Stevenson, D.; Lucas, M. C.; Reischmann, N.; Vennin, C.; Conway, J. R. W.; Boulghourjian, A.; Zaratzian, A.; Law, A. M.; Gallego-Ortega, D.; Ormandy, C. J.; Walters, S. N.; Grey, S. T.; Bailey, J.; Chtanova, T.; Quinn, J. M. W.; Baldock, P. A.; Croucher, P. I.; Schwarz, J. P.; Mrowinska, A.; Zhang, L.; Herzog, H.; Masedunskas, A.; Hardeman, E. C.; Gunning, P. W.; Del Monte-Nieto, G.; Harvey, R. P.; Samuel, M. S.; Pajic, M.; McGhee, E. J.; Johnsson, A. E.; Sansom, O. J.; Welch, H. C. E.; Morton, J. P.; Strathdee, D.; Anderson, K. I.; Timpson, P.
Cell Reports 21 (1) :274-288, 2017 10.1016/j.celrep.2017.09.022