Publications

11 items matching your search terms.

Overcoming the senescence-associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer

Chambers, C. R.; Ritchie, S.; Pereira, B. A.; Timpson, P.

Molecular Oncology 15 (12) :3242-3255, 2021 10.1002/1878-0261.13042

Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

Murphy, K. J.; Reed, D. A.; Vennin, C.; Conway, J. R. W.; Nobis, M.; Yin, J. X.; Chambers, C. R.; Pereira, B. A.; Lee, V.; Filipe, E. C.; Trpceski, M.; Ritchie, S.; Lucas, M. C.; Warren, S. C.; Skhinas, J. N.; Magenau, A.; Metcalf, X. L.; Stoehr, J.; Major, G.; Parkin, A.; Bidanel, R.; Lyons, R. J.; Zaratzian, A.; Tayao, M.; Da Silva, A.; Abdulkhalek, L.; Australian Pancreatic Genome, Initiative; Australian Pancreatic Cancer Matrix, Atlas; Gill, A. J.; Johns, A. L.; Biankin, A. V.; Samra, J.; Grimmond, S. M.; Chou, A.; Goetz, J. G.; Samuel, M. S.; Lyons, J. G.; Burgess, A.; Caldon, C. E.; Horvath, L. G.; Daly, R. J.; Gadegaard, N.; Wang, Y.; Sansom, O. J.; Morton, J. P.; Cox, T. R.; Pajic, M.; Herrmann, D.; Timpson, P.

Science Advances 7 (40) :eabh0363, 2021 10.1126/sciadv.abh0363

Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition

Sharbeen, G.; McCarroll, J. A.; Akerman, A.; Kopecky, C.; Youkhana, J.; Kokkinos, J.; Holst, J.; Boyer, C.; Erkan, M.; Goldstein, D.; Timpson, P.; Cox, T. R.; Pereira, B. A.; Chitty, J. L.; Fey, S. K.; Najumudeen, A. K.; Campbell, A. D.; Sansom, O. J.; Ignacio, R. M. C.; Naim, S.; Liu, J.; Russia, N.; Lee, J.; Chou, A.; Johns, A.; Gill, A. J.; Gonzales-Aloy, E.; Gebski, V.; Guan, Y. F.; Pajic, M.; Turner, N.; Apte, M. V.; Davis, T. P.; Morton, J. P.; Haghighi, K. S.; Kasparian, J.; McLean, B. J.; Setargew, Y. F.; Phillips, P. A.; Australian Pancreatic Cancer Genome, Initiative

CANCER RESEARCH 81 (13) :3461-3479, 2021 10.1158/0008-5472.CAN-20-2496

Dynamic Stromal Alterations Influence Tumor-Stroma Crosstalk to Promote Pancreatic Cancer and Treatment Resistance

Murphy, K. J.; Chambers, C. R.; Herrmann, D.; Timpson, P.; Pereira, B. A.

Cancers 13 (14) 2021 10.3390/cancers13143481

Mast Cell-Derived SAMD14 Is a Novel Regulator of the Human Prostate Tumor Microenvironment

Teng, L. K. H.; Pereira, B. A.; Keerthikumar, S.; Huang, C.; Niranjan, B.; Lee, S. N.; Richards, M.; Schittenhelm, R. B.; Furic, L.; Goode, D. L.; Lawrence, M. G.; Taylor, R. A.; Ellem, S. J.; Risbridger, G. P.; Lister, N. L.

Cancers 13 (6) 2021 10.3390/cancers13061237

Ex vivo culture of intact human patient derived pancreatic tumour tissue

Kokkinos, J.; Sharbeen, G.; Haghighi, K. S.; Ignacio, R. M. C.; Kopecky, C.; Gonzales-Aloy, E.; Youkhana, J.; Timpson, P.; Pereira, B. A.; Ritchie, S.; Pandzic, E.; Boyer, C.; Davis, T. P.; Butler, L. M.; Goldstein, D.; McCarroll, J. A.; Phillips, P. A.

Scientific Reports 11 (1) :1944, 2021 10.1038/s41598-021-81299-0

Stromal cell diversity associated with immune evasion in human triple-negative breast cancer

Wu, S. Z.; Roden, D. L.; Wang, C.; Holliday, H.; Harvey, K.; Cazet, A. S.; Murphy, K. J.; Pereira, B.; Al-Eryani, G.; Bartonicek, N.; Hou, R.; Torpy, J. R.; Junankar, S.; Chan, C. L.; Lam, C. E.; Hui, M. N.; Gluch, L.; Beith, J.; Parker, A.; Robbins, E.; Segara, D.; Mak, C.; Cooper, C.; Warrier, S.; Forrest, A.; Powell, J.; O'Toole, S.; Cox, T. R.; Timpson, P.; Lim, E.; Liu, X. S.; Swarbrick, A.

EMBO JOURNAL 1 (39) :e104063, 2020 10.15252/embj.2019104063

Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer

Lawrence, M. G.; Pidsley, R.; Niranjan, B.; Papargiris, M.; Pereira, B. A.; Richards, M.; Teng, L.; Norden, S.; Ryan, A.; Frydenberg, M.; Stirzaker, C.; Taylor, R. A.; Risbridger, G. P.; Clark, S. J.

Clinical Epigenetics 12 (1) :48, 2020 10.1186/s13148-020-00836-2

Targeting genetically-tuned CAFs in pancreatic cancer via perlecan manipulation

Ritchie, S.; Pereira, B. A.; Vennin, C.; Timpson, P.

EXPERT OPINION ON THERAPEUTIC TARGETS 24 (3) :171-174, 2020 10.1080/14728222.2020.1727887

CAF subpopulations: A new reservoir of stromal targets in pancreatic cancer

Pereira, B. A.; Vennin, C.; Papanicolaou, M.; Chambers, C. R.; Herrmann, D.; Morton, J. P.; Cox, T. R.; Timpson, P.

Trends in Cancer 5 (11) :724-741, 2019 10.1016/j.trecan.2019.09.010

Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment.

Nguyen, E. V.; Pereira, B. A.; Lawrence, M. G.; Ma, X.; Rebello, R. J.; Chan, H.; Niranjan, B.; Wu, Y.; Ellem, S.; Guan, X.; Wu, J.; Skhinas, J. N.; Cox, T. R.; Risbridger, G. P.; Taylor, R. A.; Lister, N. L.; Daly, R. J.

MOLECULAR & CELLULAR PROTEOMICS 18 (7) :1410-1427, 2019 10.1074/mcp.RA119.001496