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17 items matching your search terms.
Anti-Ro60 and anti-Ro52/TRIM21: Two distinct autoantibodies in systemic autoimmune diseases
Lee, A. Y. S.; Reed, J. H.; Gordon, T. P.
JOURNAL OF AUTOIMMUNITY 124 :102724, 2021 10.1016/j.jaut.2021.102724
Human transitional and IgM(low) mature naive B cells preserve permissive B-cell receptors
Zhang, Z., Jara, C. J., Singh, M., Xu, H., Goodnow, C. C., Jackson, K. J.,Reed, J. H.
IMMUNOLOGY AND CELL BIOLOGY 2021 10.1111/imcb.12478
When B cells break bad: development of pathogenic B cells in Sjogren's syndrome
Reed, J. H.; Verstappen, G. M.; Rischmueller, M.; Bryant, V. L.
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 38 Suppl 126 (4) :271-282, 2020
Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody
Singh, M.; Jackson, K. J. L.; Wang, J. J.; Schofield, P.; Field, M. A.; Koppstein, D.; Peters, T. J.; Burnett, D. L.; Rizzetto, S.; Nevoltris, D.; Masle-Farquhar, E.; Faulks, M. L.; Russell, A.; Gokal, D.; Hanioka, A.; Horikawa, K.; Colella, A. D.; Chataway, T. K.; Blackburn, J.; Mercer, T. R.; Langley, D. B.; Goodall, D. M.; Jefferis, R.; Gangadharan Komala, M.; Kelleher, A. D.; Suan, D.; Rischmueller, M.; Christ, D.; Brink, R.; Luciani, F.; Gordon, T. P.; Goodnow, C. C.; Reed, J. H.
CELL 180 (5) :878-894 e19, 2020 10.1016/j.cell.2020.01.029
OpenAccess publication Activated PI3Kdelta breaches multiple B cell tolerance checkpoints and causes autoantibody production
Lau, A.; Avery, D. T.; Jackson, K.; Lenthall, H.; Volpi, S.; Brigden, H.; Russell, A. J.; Bier, J.; Reed, J. H.; Smart, J. M.; Cole, T.; Choo, S.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Uzel, G.; Notarangelo, L. D.; Brink, R.; Goodnow, C. C.; Tangye, S. G.; Deenick, E. K.
JOURNAL OF EXPERIMENTAL MEDICINE 217 (2) :e20191336, 2020 10.1084/jem.20191336
Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity
Burnett, D. L.; Reed, J. H.; Christ, D.; Goodnow, C. C.
IMMUNOLOGICAL REVIEWS 292 (1) :61-75, 2019 10.1111/imr.12808
OpenAccess publication DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns
Skvortsova, K.; Masle-Farquhar, E.; Luu, P. L.; Song, J. Z.; Qu, W.; Zotenko, E.; Gould, C. M.; Du, Q.; Peters, T. J.; Colino-Sanguino, Y.; Pidsley, R.; Nair, S. S.; Khoury, A.; Smith, G. C.; Miosge, L. A.; Reed, J. H.; Kench, J. G.; Rubin, M. A.; Horvath, L.; Bogdanovic, O.; Lim, S. M.; Polo, J. M.; Goodnow, C. C.; Stirzaker, C.; Clark, S. J.
CANCER CELL 35 (2) :297-314 e8, 2019 10.1016/j.ccell.2019.01.004
Molecular profiling and clonal tracking of secreted rheumatoid factors in primary Sjogren's syndrome
Wang, J. J.; Reed, J. H.; Colella, A. D.; Russell, A. J.; Murray-Brown, W.; Chataway, T. K.; Jackson, K. J. L.; Goodnow, C. C.; Gordon, T. P.
Arthritis & Rheumatology 70 (10) :1617-1625, 2018 10.1002/art.40539
Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood
Schofield, P.; Vazquez-Lombardi, R.; Abdelatti, M.; Nevoltris, D.; Goodnow, C. C.; Christ, D.; Reed, J. H.
Methods in Molecular Biology 1827 :287-309, 2018 10.1007/978-1-4939-8648-4_15
B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle
Rizzetto, S.; Koppstein, D. N. P.; Samir, J.; Singh, M.; Reed, J. H.; Cai, C. H.; Lloyd, A. R.; Eltahla, A. A.; Goodnow, C. C.; Luciani, F.
Bioinformatics 34 (16) :2846-2847, 2018 10.1093/bioinformatics/bty203
Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination
Burnett, D. L.; Langley, D. B.; Schofield, P.; Hermes, J. R.; Chan, T. D.; Jackson, J.; Bourne, K.; Reed, J. H.; Patterson, K.; Porebski, B. T.; Brink, R.; Christ, D.; Goodnow, C. C.
SCIENCE 360 (6385) :223-226, 2018 10.1126/science.aao3859
IgV peptide mapping of native Ro60 autoantibody proteomes in primary Sjogren's syndrome reveals molecular markers of Ro/La diversification
Wang, J. J.; Al Kindi, M. A.; Colella, A. D.; Dykes, L.; Jackson, M. W.; Chataway, T. K.; Reed, J. H.; Gordon, T. P.;
CLINICAL IMMUNOLOGY 173 :57-63, 2016
OpenAccess publication Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization
Reed, J.; Jackson, J.; Christ, D.; Goodnow.CG.
JOURNAL OF EXPERIMENTAL MEDICINE 213 (7) :1255-65, 2016
OpenAccess publication Targeting downstream transcription factors and epigenetic modifications following Toll-like receptor 7/8 ligation to forestall tissue injury in anti-Ro60 associated heart block.
Clancy, R. M.; Markham, A. J.; Reed, J. H.; Blumenberg, M.; Halushka, M. K.; Buyon, J. P.;
JOURNAL OF AUTOIMMUNITY 67 :36-45, 2016
OpenAccess publication IgD attenuates the IgM-induced anergy response in transitional and mature B cells
Sabouri, Z. ; Perotti, S. ; Spierings, E. ; Humburg, P. ; Yabas, M. ; Bergmann, H. ; Horikawa, K. ; Roots, C. ; Lambe, S. ; Young, C. ; Andrews, T. D. ; Field, M. ; Enders, A. ; Reed, J. H. ; Goodnow, C. C.;
Nature Communications 7 :13381, 2016
OpenAccess publication A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition.
Goff, D. J.; Recart, A. C.; Sadarangani, A.; Chun, H. J.; Barrett, C. L.; Krajewska, M.; Leu, H.; Low-Marchelli, J.; Ma, W.; Shih, A. Y.; Wei, J.; Zhai, D.; Geron, I.; Pu, M.; Bao, L.; Chuang, R.; Balaian, L.; Gotlib, J.; Minden, M.; Martinelli, G.; Rusert, J.; Dao, K. H.; Shazand, K.; Wentworth, P.; Smith, K. M.; Jamieson, C. A.; Morris, S. R.; Messer, K.; Goldstein, L. S.; Hudson, T. J.; Marra, M.; Frazer, K. A.; Pellecchia, M.; Reed, J. C.; Jamieson, C. H.;
Cell Stem Cell 12 (3) :316-28, 2013 10.1016/j.stem.2012.12.011