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11 items matching your search terms.
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
Vennin, C.; Melenec, P.; Rouet, R.; Nobis, M.; Cazet, A. S.; Murphy, K. J.; Herrmann, D.; Reed, D. A.; Lucas, M. C.; Warren, S. C.; Elgundi, Z.; Pinese, M.; Kalna, G.; Roden, D.; Samuel, M.; Zaratzian, A.; Grey, S. T.; Da Silva, A.; Leung, W.; Mathivanan, S.; Wang, Y.; Braithwaite, A. W.; Christ, D.; Benda, A.; Parkin, A.; Phillips, P. A.; Whitelock, J. M.; Gill, A. J.; Sansom, O. J.; Croucher, D. R.; Parker, B. L.; Pajic, M.; Morton, J. P.; Cox, T. R.; Timpson, P.
Nature Communications 10 (1) :3637, 2019 10.1038/s41467-019-10968-6
A Niche-Dependent Myeloid Transcriptome Signature Defines Dormant Myeloma Cells
Khoo, W. H.; Ledergor, G.; Weiner, A.; Roden, D. L.; Terry, R. L.; McDonald, M. M.; Chai, R. C.; De Veirman, K.; Owen, K. L.; Opperman, K. S.; Vandyke, K.; Clark, J. R.; Seckinger, A.; Kovacic, N.; Nguyen, A.; Mohanty, S. T.; Pettitt, J. A.; Xiao, Y.; Corr, A. P.; Seeliger, C.; Novotny, M.; Lasken, R. S.; Nguyen, T. V.; Oyajobi, B. O.; Aftab, D.; Swarbrick, A.; Parker, B.; Hewett, D. R.; Hose, D.; Vanderkerken, K.; Zannettino, A. C. W.; Amit, I.; Phan, T. G.; Croucher, P. I.
Blood 134 (1) :30-43, 2019 10.1182/blood.2018880930
OpenAccess publication A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation
Oakes, S. R.; Gallego-Ortega, D.; Stanford, P. M.; Junankar, S.; Au, W. W. Y.; Kikhtyak, Z.; von Korff, A.; Sergio, C. M.; Law, A. M. K.; Castillo, L. E.; Allerdice, S. L.; Young, A. I. J.; Piggin, C.; Whittle, B.; Bertram, E.; Naylor, M. J.; Roden, D. L.; Donovan, J.; Korennykh, A.; Goodnow, C. C.; O'Bryan, M. K.; Ormandy, C. J.
PLoS Genetics 13 (11) :e1007072, 2017 10.1371/journal.pgen.1007072
OpenAccess publication Damage-inducible intragenic demethylation of the human TP53 tumor suppressor gene is associated with transcription from an alternative intronic promoter
Blackburn, J.; Roden, D. L.; Ng, R.; Wu, J.; Bosman, A.; Epstein, R. J.;
MOLECULAR CARCINOGENESIS 55 (12) :1940-1951, 2016
OpenAccess publication ELF5 isoform expression is tissue-specific and significantly altered in cancer
Piggin, C.; Roden, D.; Gallego-Ortega, D.; Lee, H.; Oakes, S.; Ormandy, C.;
BREAST CANCER RES 18 (1) :4, 2016
OpenAccess publication ELF5 drives lung metastasis in luminal breast cancer through recruitment of Gr1+ CD11b+ myeloid-derived suppressor cells
Gallego-Ortega, D.; Ledger, A.; Roden, D. L.; Law, A. M.; Magenau, A.; Kikhtyak, Z.; Cho, C.; Allerdice, S. L.; Lee, H. J.; Valdes-Mora, F.; Herrmann, D.; Salomon, R.; Young, A. I.; Lee, B. Y.; Sergio, C. M.; Kaplan, W.; Piggin, C.; Conway, J. R.; Rabinovich, B.; Millar, E. K.; Oakes, S. R.; Chtanova, T.; Swarbrick, A.; Naylor, M. J.; O'Toole, S.; Green, A. R.; Timpson, P.; Gee, J. M.; Ellis, I. O.; Clark, S. J.; Ormandy, C. J.;
PLOS BIOL 13 (12) :e1002330, 2015 10.1371/journal.pbio.1002330
OpenAccess publication ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype
Junankar, S.; Baker, L. A.; Roden, D. L.; Nair, R.; Elsworth, B.; Gallego-Ortega, D.; Lacaze, P.; Cazet, A.; Nikolic, I.; Teo, W. S.; Yang, J.; McFarland, A.; Harvey, K.; Naylor, M. J.; Lakhani, S. R.; Simpson, P. T.; Raghavendra, A.; Saunus, J.; Madore, J.; Kaplan, W.; Ormandy, C.; Millar, E. K.; O'Toole, S.; Yun, K.; Swarbrick, A.;
Nature Communications 6 :6548, 2015
OpenAccess publication Telling the tiger by its stripes: mapping the genomics of kidney graft tolerance in real time
Roden, D. L.; Grey, S. T.;
KIDNEY INTERNATIONAL 87 (5) :875-7, 2015
OpenAccess publication MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene
Phua, Y. W.; Nguyen, A.; Roden, D. L.; Elsworth, B.; Deng, N.; Nikolic, I.; Yang, J.; McFarland, A.; Russell, R.; Kaplan, W.; Cowley, M. J.; Nair, R.; Zotenko, E.; O'Toole, S.; Tan, S. X.; James, D. E.; Clark, S. J.; Kouros-Mehr, H.; Swarbrick, A.;
BREAST CANCER RES 17 :83, 2015
OpenAccess publication c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer
Nair, R.; Roden, D. L.; Teo, W. S.; McFarland, A.; Junankar, S.; Ye, S.; Nguyen, A.; Yang, J.; Nikolic, I.; Hui, M.; Morey, A.; Shah, J.; Pfefferle, A. D.; Usary, J.; Selinger, C.; Baker, L. A.; Armstrong, N.; Cowley, M. J.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Herschkowitz, J. I.; Perou, C. M.; Kaplan, W.; O'Toole, S. A.; Swarbrick, A
ONCOGENE 33 (30) :3992-4002, 2014
OpenAccess publication ELF5 supresses estrogen sensitivity and underpins the acquisition of anitestrogen resistance in luminal breast cancer.
Kalyuga, M.; Gallego-Ortega, D.; Lee, H. J.; Roden, D. L.; Cowley, M. J.; Caldon, C. E.; Stone, A.; Allerdice, S. L.; Valdes-Mora, F.; Launchbury, R.; Statham, A. L.; Armstrong, N.; Alles, M. C.; Young, A.; Egger, A.; Au, W.; Piggin, C. L.; Evans, C. J.; Ledger, A.; Brummer, T.; Oakes, S. R.; Kaplan, W.; Gee, J. M.; Nicholson, R. I.; Sutherland, R. L.; Swarbrick, A.; Naylor, M. J.; Clark, S. J.; Carroll, J. S.; Ormandy, C. J.;
PLOS BIOL 10 (12) :e1001461, 2012 10.1371/journal.pbio.1001461