Garvan Institute of Medical Research

44 items matching your search terms.

Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance: Brandon, A. E.; Liao, B. M.; Diakanastasis, B.; Parker, B. L.; Raddatz, K.; McManus, S. A.; O'Reilly, L.; Kimber, E.; van der Kraan, A. G.; Hancock, D.; Henstridge, D. C.; Meikle, P. J.; Cooney, G. J.; James, D. E.; Reibe, S.; Febbraio, M. A.; Biden, T. J.; Schmitz-Peiffer, C.; Cell Metabolism 29 (1) :183-191 e7, 2019 10.1016/j.cmet.2018.09.013

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism: Turner, N.; Lim, X. Y.; Toop, H. D.; Osborne, B.; Brandon, A. E.; Taylor, E. N.; Fiveash, C. E.; Govindaraju, H.; Teo, J. D.; McEwen, H. P.; Couttas, T. A.; Butler, S. M.; Das, A.; Kowalski, G. M.; Bruce, C. R.; Hoehn, K. L.; Fath, T.; Schmitz-Peiffer, C.; Cooney, G. J.; Montgomery, M. K.; Morris, J. C.; Don, A. S.; Nature Communications 9 (1) :3165, 2018 10.1038/s41467-018-05613-7

Anarchy in the UPR: A Ca(2+)-insensitive PKC inhibits SERCA activity to promote ER stress: Schmitz-Peiffer, C.; BIOSCIENCE REPORTS :pii: BSR20170966, 2018 10.1042/BSR20170966

Characterization of peptide interactions that regulate PKCÎµ activation: Chandrashekaran, I. R., Norton, R. S., Schmitz-Peiffer, C.; FEBS LETTERS 592 (2) :179-189, 2018 10.1002/1873-3468.12953

Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species: Montgomery, M. K.; Brown, S. H.; Lim, X. Y.; Fiveash, C. E.; Osborne, B.; Bentley, N. L.; Braude, J. P.; Mitchell, T. W.; Coster, A. C.; Don, A. S.; Cooney, G. J.; Schmitz-Peiffer, C.; Turner, N.;; BBA-MOL BASIS DIS 1861 (11) :1828-1839, 2016

Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes: Liao, B. M.1, McManus, S. A.1, Hughes, W. E.1,2, Schmitz-Peiffer, C.1,2; 1 Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, New South Wales, 2010, Australia; 2 St. Vincent's Hospital Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, 2052, Australia; MOLECULAR ENDOCRINOLOGY 30 (4) :417-28, 2016

Proteomic analysis of livers from fat-fed mice deficient in either PKCdelta or PKCepsilon identifies Htatip2 as a regulator of lipid metabolism: Liao, B. M.; Raddatz, K.; Zhong, L.; Parker, B. L.; Raftery, M. J.; Schmitz-Peiffer, C.;; PROTEOMICS 14 (21-22) :2578-87, 2014

Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment: Frangioudakis, G. ; Diakanastasis, B. ; Liao, B. Q. ; Saville, J. T. ; Hoffman, N. J. ; Mitchell, T. W. ; Schmitz-Peiffer, C.;; DIABETOLOGIA 56 (12) :2697-701, 2013

Protein kinase Cepsilon modulates insulin receptor localization and trafficking in mouse embryonic fibroblasts: Pedersen, D. J.; Diakanastasis, B. ; Stockli, J. ; Schmitz-Peiffer, C.;; PLoS One 8 (3) :e58046, 2013

Deletion of protein kinase Cepsilon in mice has limited effects on liver metabolite levels but alters fasting ketogenesis and gluconeogenesis: Raddatz, K.; Frangioudakis, G.; Diakanastasis, B.; Liao, B. M.; Leitges, M.; Schmitz-Peiffer, C.; DIABETOLOGIA 55 (10) :2789-93, 2012 10.1007/s00125-012-2647-5

Lysophosphatidic acid induces early growth response-1 (Egr-1) protein expression via protein kinase Cdelta-regulated extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activation in vascular smooth muscle cells: Iyoda, T.; Zhang, F.; Sun, L.; Hao, F.; Schmitz-Peiffer, C.; Xu, X.; Cui, M. Z.;; JOURNAL OF BIOLOGICAL CHEMISTRY 287 (27) :22635-42, 2012

Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors: Luo, X.; Hutley, L. J.; Webster, J. A.; Kim, Y. H.; Liu, D. F.; Newell, F. S.; Widberg, C. H.; Bachmann, A.; Turner, N.; Schmitz-Peiffer, C.; Prins, J. B.; Yang, G. S.; Whitehead, J. P.;; DIABETES 61 (1) :124-36, 2012

Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice: Raddatz, K.; Turner, N.; Frangioudakis, G.; Liao, B. M.; Pedersen, D. J.; Cantley, J.; Wilks, D.; Preston, E.; Hegarty, B. D.; Leitges, M.; Raftery, M. J.; Biden, T. J.; Schmitz-Peiffer, C.; DIABETOLOGIA 54 (6) :1447-56, 2011