Publications

184 items matching your search terms.

Genetic and structural basis of the human anti-alpha-galactosyl antibody response

Langley, D. B.; Schofield, P.; Nevoltris, D.; Jackson, J.; Jackson, K. J. L.; Peters, T. J.; Burk, M.; Matthews, J. M.; Basten, A.; Goodnow, C. C.; van Nunen, S.; Reed, J. H.; Christ, D.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 119 (28) :e2123212119, 2022 10.1073/pnas.2123212119

Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability

Burnett, D. L.; Jackson, K. J. L.; Langley, D. B.; Aggrawal, A.; Stella, A. O.; Johansen, M. D.; Balachandran, H.; Lenthall, H.; Rouet, R.; Walker, G.; Saunders, B. M.; Singh, M.; Li, H.; Henry, J. Y.; Jackson, J.; Stewart, A. G.; Witthauer, F.; Spence, M. A.; Hansbro, N. G.; Jackson, C.; Schofield, P.; Milthorpe, C.; Martinello, M.; Schulz, S. R.; Roth, E.; Kelleher, A.; Emery, S.; Britton, W. J.; Rawlinson, W. D.; Karl, R.; Schafer, S.; Winkler, T. H.; Brink, R.; Bull, R. A.; Hansbro, P. M.; Jack, H. M.; Turville, S.; Christ, D.; Goodnow, C. C.

IMMUNITY 54 (12) :2908-2921 e6, 2021 10.1016/j.immuni.2021.10.019

A recombinant antibody fragment directed to the thymic stromal lymphopoietin receptor (CRLF2) efficiently targets pediatric Philadelphia chromosome-like acute lymphoblastic leukemia

Mohamed, S. M. A.; Wohlmann, A.; Schofield, P.; Sia, K. C. S.; McCalmont, H.; Savvides, S. N.; Verstraete, K.; Kavallaris, M.; Christ, D.; Friedrich, K. H.; Bayat, N.; Lock, R. B.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 190 :214-223, 2021 10.1016/j.ijbiomac.2021.08.194

NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers

Sun, Y.; Yang, N.; Utama, F. E.; Udhane, S. S.; Zhang, J.; Peck, A. R.; Yanac, A.; Duffey, K.; Langenheim, J. F.; Udhane, V.; Xia, G.; Peterson, J. F.; Jorns, J. M.; Nevalainen, M. T.; Rouet, R.; Schofield, P.; Christ, D.; Ormandy, C. J.; Rosenberg, A. L.; Chervoneva, I.; Tsaih, S. W.; Flister, M. J.; Fuchs, S. Y.; Wagner, K. U.; Rui, H.

Science Advances 7 (38) :eabc8145, 2021 10.1126/sciadv.abc8145

Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

Rouet, R.; Mazigi, O.; Walker, G. J.; Langley, D. B.; Sobti, M.; Schofield, P.; Lenthall, H.; Jackson, J.; Ubiparipovic, S.; Henry, J. Y.; Abayasingam, A.; Burnett, D.; Kelleher, A.; Brink, R.; Bull, R. A.; Turville, S.; Stewart, A. G.; Goodnow, C. C.; Rawlinson, W. D.; Christ, D.

mAbs 13 (1) :1922134, 2021 10.1080/19420862.2021.1922134

DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells

King, J. J.; Irving, K. L.; Evans, C. W.; Chikhale, R. V.; Becker, R.; Morris, C. J.; Pena Martinez, C. D.; Schofield, P.; Christ, D.; Hurley, L. H.; Waller, Z. A. E.; Iyer, K. S.; Smith, N. M.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 142 (49) :20600-20604, 2020 10.1021/jacs.0c11708

Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens

Burnett, D. L.; Schofield, P.; Langley, D. B.; Jackson, J.; Bourne, K.; Wilson, E.; Porebski, B. T.; Buckle, A. M.; Brink, R.; Goodnow, C. C.; Christ, D.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (36) :22341-22350, 2020 10.1073/pnas.2005102117

De Novo Gene Variants and Familial Bipolar Disorder

Toma, C.; Shaw, A. D.; Overs, B. J.; Mitchell, P. B.; Schofield, P. R.; Cooper, A. A.; Fullerton, J. M.

JAMA Network Open 3 (5) :e203382, 2020 10.1001/jamanetworkopen.2020.3382

Mapping the extent of heterogeneity of human CCR5+ CD4+ T cells in peripheral blood and lymph nodes

Zaunders, J.; Munier, C. M. L.; McGuire, H. M.; Law, H.; Howe, A.; Xu, Y.; de St Groth, B. F.; Schofield, P.; Christ, D.; Milner, B.; Obeid, S.; Dyer, W. B.; Saksena, N. K.; Kelleher, A. D.

AIDS 34 (6) :833-848, 2020 10.1097/QAD.0000000000002503

Systematic functional identification of cancer multi-drug resistance genes

Lau MT., Ghazanfar S., Parkin A., Chou A., Rouaen JR., Littleboy JB., Nessem D., Khuong TM., Nevoltris D., Schofield P., Langley D., Christ D., Yang J., Pajic M., Neely GG.

GENOME BIOLOGY 21 (1) :27, 2020 https://doi.org/10.1186/s13059-020-1940-8

Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody

Singh, M.; Jackson, K. J. L.; Wang, J. J.; Schofield, P.; Field, M. A.; Koppstein, D.; Peters, T. J.; Burnett, D. L.; Rizzetto, S.; Nevoltris, D.; Masle-Farquhar, E.; Faulks, M. L.; Russell, A.; Gokal, D.; Hanioka, A.; Horikawa, K.; Colella, A. D.; Chataway, T. K.; Blackburn, J.; Mercer, T. R.; Langley, D. B.; Goodall, D. M.; Jefferis, R.; Gangadharan Komala, M.; Kelleher, A. D.; Suan, D.; Rischmueller, M.; Christ, D.; Brink, R.; Luciani, F.; Gordon, T. P.; Goodnow, C. C.; Reed, J. H.

CELL 180 (5) :878-894 e19, 2020 10.1016/j.cell.2020.01.029

Protein A superantigen: structure, engineering and molecular basis of antibody recognition

Mazigi, O.; Schofield, P.; Langley, D. B.; Christ, D.

Protein Eng 32 (8) :359-366, 2019 10.1093/protein/gzz026

GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS

Tsai, V. W.; Zhang, H. P.; Manandhar, R.; Schofield, P.; Christ, D.; Lee-Ng, K. K. M.; Lebhar, H.; Marquis, C. P.; Husaini, Y.; Brown, D. A.; Breit, S. N.

INTERNATIONAL JOURNAL OF OBESITY 43 (12) :2370-2380, 2019 10.1038/s41366-019-0365-5

Human Antibody Bispecifics through Phage Display Selection

Luthra, A.; Langley, D. B.; Schofield, P.; Jackson, J.; Abdelatti, M.; Rouet, R.; Nevoltris, D.; Mazigi, O.; Crossett, B.; Christie, M.; Christ, D.

Biochemistry 58 (13) :1701-1704, 2019 10.1021/acs.biochem.9b00037

Expression of Human VH Single Domains as Fc Fusions in Mammalian Cells

Abdelatti, M.; Schofield, P.; Christ, D.

Methods in Molecular Biology 1953 :121-136, 2019 10.1007/978-1-4939-9145-7_8

Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood

Schofield, P.; Vazquez-Lombardi, R.; Abdelatti, M.; Nevoltris, D.; Goodnow, C. C.; Christ, D.; Reed, J. H.

Methods in Molecular Biology 1827 :287-309, 2018 10.1007/978-1-4939-8648-4_15