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183 items matching your search terms.
Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability
Burnett, D. L.; Jackson, K. J. L.; Langley, D. B.; Aggrawal, A.; Stella, A. O.; Johansen, M. D.; Balachandran, H.; Lenthall, H.; Rouet, R.; Walker, G.; Saunders, B. M.; Singh, M.; Li, H.; Henry, J. Y.; Jackson, J.; Stewart, A. G.; Witthauer, F.; Spence, M. A.; Hansbro, N. G.; Jackson, C.; Schofield, P.; Milthorpe, C.; Martinello, M.; Schulz, S. R.; Roth, E.; Kelleher, A.; Emery, S.; Britton, W. J.; Rawlinson, W. D.; Karl, R.; Schafer, S.; Winkler, T. H.; Brink, R.; Bull, R. A.; Hansbro, P. M.; Jack, H. M.; Turville, S.; Christ, D.; Goodnow, C. C.
IMMUNITY 54 (12) :2908-2921 e6, 2021 10.1016/j.immuni.2021.10.019
A recombinant antibody fragment directed to the thymic stromal lymphopoietin receptor (CRLF2) efficiently targets pediatric Philadelphia chromosome-like acute lymphoblastic leukemia
Mohamed, S. M. A.; Wohlmann, A.; Schofield, P.; Sia, K. C. S.; McCalmont, H.; Savvides, S. N.; Verstraete, K.; Kavallaris, M.; Christ, D.; Friedrich, K. H.; Bayat, N.; Lock, R. B.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 190 :214-223, 2021 10.1016/j.ijbiomac.2021.08.194
NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers
Sun, Y.; Yang, N.; Utama, F. E.; Udhane, S. S.; Zhang, J.; Peck, A. R.; Yanac, A.; Duffey, K.; Langenheim, J. F.; Udhane, V.; Xia, G.; Peterson, J. F.; Jorns, J. M.; Nevalainen, M. T.; Rouet, R.; Schofield, P.; Christ, D.; Ormandy, C. J.; Rosenberg, A. L.; Chervoneva, I.; Tsaih, S. W.; Flister, M. J.; Fuchs, S. Y.; Wagner, K. U.; Rui, H.
Science Advances 7 (38) :eabc8145, 2021 10.1126/sciadv.abc8145
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies
Rouet, R.; Mazigi, O.; Walker, G. J.; Langley, D. B.; Sobti, M.; Schofield, P.; Lenthall, H.; Jackson, J.; Ubiparipovic, S.; Henry, J. Y.; Abayasingam, A.; Burnett, D.; Kelleher, A.; Brink, R.; Bull, R. A.; Turville, S.; Stewart, A. G.; Goodnow, C. C.; Rawlinson, W. D.; Christ, D.
mAbs 13 (1) :1922134, 2021 10.1080/19420862.2021.1922134
DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells
King, J. J.; Irving, K. L.; Evans, C. W.; Chikhale, R. V.; Becker, R.; Morris, C. J.; Pena Martinez, C. D.; Schofield, P.; Christ, D.; Hurley, L. H.; Waller, Z. A. E.; Iyer, K. S.; Smith, N. M.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 142 (49) :20600-20604, 2020 10.1021/jacs.0c11708
Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens
Burnett, D. L.; Schofield, P.; Langley, D. B.; Jackson, J.; Bourne, K.; Wilson, E.; Porebski, B. T.; Buckle, A. M.; Brink, R.; Goodnow, C. C.; Christ, D.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (36) :22341-22350, 2020 10.1073/pnas.2005102117
De Novo Gene Variants and Familial Bipolar Disorder
Toma, C.; Shaw, A. D.; Overs, B. J.; Mitchell, P. B.; Schofield, P. R.; Cooper, A. A.; Fullerton, J. M.
JAMA Network Open 3 (5) :e203382, 2020 10.1001/jamanetworkopen.2020.3382
Mapping the extent of heterogeneity of human CCR5+ CD4+ T cells in peripheral blood and lymph nodes
Zaunders, J.; Munier, C. M. L.; McGuire, H. M.; Law, H.; Howe, A.; Xu, Y.; de St Groth, B. F.; Schofield, P.; Christ, D.; Milner, B.; Obeid, S.; Dyer, W. B.; Saksena, N. K.; Kelleher, A. D.
AIDS 34 (6) :833-848, 2020 10.1097/QAD.0000000000002503
OpenAccess publication Systematic functional identification of cancer multi-drug resistance genes
Lau MT., Ghazanfar S., Parkin A., Chou A., Rouaen JR., Littleboy JB., Nessem D., Khuong TM., Nevoltris D., Schofield P., Langley D., Christ D., Yang J., Pajic M., Neely GG.
GENOME BIOLOGY 21 (1) :27, 2020 https://doi.org/10.1186/s13059-020-1940-8
Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody
Singh, M.; Jackson, K. J. L.; Wang, J. J.; Schofield, P.; Field, M. A.; Koppstein, D.; Peters, T. J.; Burnett, D. L.; Rizzetto, S.; Nevoltris, D.; Masle-Farquhar, E.; Faulks, M. L.; Russell, A.; Gokal, D.; Hanioka, A.; Horikawa, K.; Colella, A. D.; Chataway, T. K.; Blackburn, J.; Mercer, T. R.; Langley, D. B.; Goodall, D. M.; Jefferis, R.; Gangadharan Komala, M.; Kelleher, A. D.; Suan, D.; Rischmueller, M.; Christ, D.; Brink, R.; Luciani, F.; Gordon, T. P.; Goodnow, C. C.; Reed, J. H.
CELL 180 (5) :878-894 e19, 2020 10.1016/j.cell.2020.01.029
Protein A superantigen: structure, engineering and molecular basis of antibody recognition
Mazigi, O.; Schofield, P.; Langley, D. B.; Christ, D.
Protein Eng 32 (8) :359-366, 2019 10.1093/protein/gzz026
GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS
Tsai, V. W.; Zhang, H. P.; Manandhar, R.; Schofield, P.; Christ, D.; Lee-Ng, K. K. M.; Lebhar, H.; Marquis, C. P.; Husaini, Y.; Brown, D. A.; Breit, S. N.
INTERNATIONAL JOURNAL OF OBESITY 43 (12) :2370-2380, 2019 10.1038/s41366-019-0365-5
Human Antibody Bispecifics through Phage Display Selection
Luthra, A.; Langley, D. B.; Schofield, P.; Jackson, J.; Abdelatti, M.; Rouet, R.; Nevoltris, D.; Mazigi, O.; Crossett, B.; Christie, M.; Christ, D.
Biochemistry 58 (13) :1701-1704, 2019 10.1021/acs.biochem.9b00037
Expression of Human VH Single Domains as Fc Fusions in Mammalian Cells
Abdelatti, M.; Schofield, P.; Christ, D.
Methods in Molecular Biology 1953 :121-136, 2019 10.1007/978-1-4939-9145-7_8
Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood
Schofield, P.; Vazquez-Lombardi, R.; Abdelatti, M.; Nevoltris, D.; Goodnow, C. C.; Christ, D.; Reed, J. H.
Methods in Molecular Biology 1827 :287-309, 2018 10.1007/978-1-4939-8648-4_15
OpenAccess publication I-motif DNA structures are formed in the nuclei of human cells
Zeraati, M.; Langley, D. B.; Schofield, P.; Moye, A. L.; Rouet, R.; Hughes, W. E.; Bryan, T. M.; Dinger, M. E.; Christ, D.
Nature Chemistry 10 (6) :631-637, 2018 10.1038/s41557-018-0046-3