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98 items matching your search terms.
Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions
Jose, J.; Hoque, M.; Engel, J.; Beevi, S. S.; Wahba, M.; Georgieva, M. I.; Murphy, K. J.; Hughes, W. E.; Cochran, B. J.; Lu, A.; Tebar, F.; Hoy, A. J.; Timpson, P.; Rye, K. A.; Enrich, C.; Rentero, C.; Grewal, T.
Scientific Reports 12 (1) :596, 2022 10.1038/s41598-021-04584-y
Overcoming the senescence-associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer
Chambers, C. R.; Ritchie, S.; Pereira, B. A.; Timpson, P.
Molecular Oncology 15 (12) :3242-3255, 2021 10.1002/1878-0261.13042
Quantifying and visualising the nuances of cellular dynamics in vivo using intravital imaging
Murphy, K. J.; Reed, D. A.; Trpceski, M.; Herrmann, D.; Timpson, P.
CURRENT OPINION IN CELL BIOLOGY 72 :41-53, 2021 10.1016/
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status
Murphy, K. J.; Reed, D. A.; Vennin, C.; Conway, J. R. W.; Nobis, M.; Yin, J. X.; Chambers, C. R.; Pereira, B. A.; Lee, V.; Filipe, E. C.; Trpceski, M.; Ritchie, S.; Lucas, M. C.; Warren, S. C.; Skhinas, J. N.; Magenau, A.; Metcalf, X. L.; Stoehr, J.; Major, G.; Parkin, A.; Bidanel, R.; Lyons, R. J.; Zaratzian, A.; Tayao, M.; Da Silva, A.; Abdulkhalek, L.; Australian Pancreatic Genome, Initiative; Australian Pancreatic Cancer Matrix, Atlas; Gill, A. J.; Johns, A. L.; Biankin, A. V.; Samra, J.; Grimmond, S. M.; Chou, A.; Goetz, J. G.; Samuel, M. S.; Lyons, J. G.; Burgess, A.; Caldon, C. E.; Horvath, L. G.; Daly, R. J.; Gadegaard, N.; Wang, Y.; Sansom, O. J.; Morton, J. P.; Cox, T. R.; Pajic, M.; Herrmann, D.; Timpson, P.
Science Advances 7 (40) :eabh0363, 2021 10.1126/sciadv.abh0363
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
Floerchinger, A.; Murphy, K. J.; Latham, S. L.; Warren, S. C.; McCulloch, A. T.; Lee, Y. K.; Stoehr, J.; Melenec, P.; Guaman, C. S.; Metcalf, X. L.; Lee, V.; Zaratzian, A.; Da Silva, A.; Tayao, M.; Rolo, S.; Phimmachanh, M.; Sultani, G.; McDonald, L.; Mason, S. M.; Ferrari, N.; Ooms, L. M.; Johnsson, A. E.; Spence, H. J.; Olson, M. F.; Machesky, L. M.; Sansom, O. J.; Morton, J. P.; Mitchell, C. A.; Samuel, M. S.; Croucher, D. R.; Welch, H. C. E.; Blyth, K.; Caldon, C. E.; Herrmann, D.; Anderson, K. I.; Timpson, P.; Nobis, M.
Cell Reports 36 (11) :109689, 2021 10.1016/j.celrep.2021.109689
Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition
Sharbeen, G.; McCarroll, J. A.; Akerman, A.; Kopecky, C.; Youkhana, J.; Kokkinos, J.; Holst, J.; Boyer, C.; Erkan, M.; Goldstein, D.; Timpson, P.; Cox, T. R.; Pereira, B. A.; Chitty, J. L.; Fey, S. K.; Najumudeen, A. K.; Campbell, A. D.; Sansom, O. J.; Ignacio, R. M. C.; Naim, S.; Liu, J.; Russia, N.; Lee, J.; Chou, A.; Johns, A.; Gill, A. J.; Gonzales-Aloy, E.; Gebski, V.; Guan, Y. F.; Pajic, M.; Turner, N.; Apte, M. V.; Davis, T. P.; Morton, J. P.; Haghighi, K. S.; Kasparian, J.; McLean, B. J.; Setargew, Y. F.; Phillips, P. A.; Australian Pancreatic Cancer Genome, Initiative
CANCER RESEARCH 81 (13) :3461-3479, 2021 10.1158/0008-5472.CAN-20-2496
Dynamic Stromal Alterations Influence Tumor-Stroma Crosstalk to Promote Pancreatic Cancer and Treatment Resistance
Murphy, K. J.; Chambers, C. R.; Herrmann, D.; Timpson, P.; Pereira, B. A.
Cancers 13 (14) 2021 10.3390/cancers13143481
Single cell transcriptome atlas of mouse mammary epithelial cells across development
Pal, B.; Chen, Y.; Milevskiy, M. J. G.; Vaillant, F.; Prokopuk, L.; Dawson, C. A.; Capaldo, B. D.; Song, X.; Jackling, F.; Timpson, P.; Lindeman, G. J.; Smyth, G. K.; Visvader, J. E.
BREAST CANCER RESEARCH 23 (1) :69, 2021 10.1186/s13058-021-01445-4
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
Samuel, M.; Fonseka, P.; Sanwlani, R.; Gangoda, L.; Chee, S. H.; Keerthikumar, S.; Spurling, A.; Chitti, S. V.; Zanker, D.; Ang, C. S.; Atukorala, I.; Kang, T.; Shahi, S.; Marzan, A. L.; Nedeva, C.; Vennin, C.; Lucas, M. C.; Cheng, L.; Herrmann, D.; Pathan, M.; Chisanga, D.; Warren, S. C.; Zhao, K.; Abraham, N.; Anand, S.; Boukouris, S.; Adda, C. G.; Jiang, L.; Shekhar, T. M.; Baschuk, N.; Hawkins, C. J.; Johnston, A. J.; Orian, J. M.; Hoogenraad, N. J.; Poon, I. K.; Hill, A. F.; Jois, M.; Timpson, P.; Parker, B. S.; Mathivanan, S.
Nature Communications 12 (1) :3950, 2021 10.1038/s41467-021-24273-8
Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP
Guo, G.; Papanicolaou, M.; Demarais, N. J.; Wang, Z.; Schey, K. L.; Timpson, P.; Cox, T. R.; Grey, A. C.
Nature Communications 12 (1) :3241, 2021 10.1038/s41467-021-23461-w
A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma
Gonzalez Rajal, A.; Marzec, K. A.; McCloy, R. A.; Nobis, M.; Chin, V.; Hastings, J. F.; Lai, K.; Kennerson, M.; Hughes, W. E.; Vaghjiani, V.; Timpson, P.; Cain, J. E.; Watkins, D. N.; Croucher, D. R.; Burgess, A.
eLife 10 2021 10.7554/eLife.65234
Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity
Yan, C.; Zeng, T.; Lee, K.; Nobis, M.; Loh, K.; Gou, L.; Xia, Z.; Gao, Z.; Bensellam, M.; Hughes, W.; Lau, J.; Zhang, L.; Ip, C. K.; Enriquez, R.; Gao, H.; Wang, Q. P.; Wu, Q.; Haigh, J. J.; Laybutt, D. R.; Timpson, P.; Herzog, H.; Shi, Y. C.
Nature Communications 12 (1) :2622, 2021 10.1038/s41467-021-22925-3
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype
Valdes-Mora, F.; Salomon, R.; Gloss, B. S.; Law, A. M. K.; Venhuizen, J.; Castillo, L.; Murphy, K. J.; Magenau, A.; Papanicolaou, M.; Rodriguez de la Fuente, L.; Roden, D. L.; Colino-Sanguino, Y.; Kikhtyak, Z.; Farbehi, N.; Conway, J. R. W.; Sikta, N.; Oakes, S. R.; Cox, T. R.; O'Donoghue, S. I.; Timpson, P.; Ormandy, C. J.; Gallego-Ortega, D.
Cell Reports 35 (2) :108945, 2021 10.1016/j.celrep.2021.108945
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
McDonald, M. M.; Khoo, W. H.; Ng, P. Y.; Xiao, Y.; Zamerli, J.; Thatcher, P.; Kyaw, W.; Pathmanandavel, K.; Grootveld, A. K.; Moran, I.; Butt, D.; Nguyen, A.; Corr, A.; Warren, S.; Biro, M.; Butterfield, N. C.; Guilfoyle, S. E.; Komla-Ebri, D.; Dack, M. R. G.; Dewhurst, H. F.; Logan, J. G.; Li, Y.; Mohanty, S. T.; Byrne, N.; Terry, R. L.; Simic, M. K.; Chai, R.; Quinn, J. M. W.; Youlten, S. E.; Pettitt, J. A.; Abi-Hanna, D.; Jain, R.; Weninger, W.; Lundberg, M.; Sun, S.; Ebetino, F. H.; Timpson, P.; Lee, W. M.; Baldock, P. A.; Rogers, M. J.; Brink, R.; Williams, G. R.; Bassett, J. H. D.; Kemp, J. P.; Pavlos, N. J.; Croucher, P. I.; Phan, T. G.
CELL 184 (5) :1330-1347 e13, 2021 10.1016/j.cell.2021.02.002
Interfacial Curvature in Confined Coculture Directs Stromal Cell Activity with Spatial Corralling of Pancreatic Cancer Cells
Nemec, S.; Lam, J.; Zhong, J.; Heu, C.; Timpson, P.; Li, Q.; Youkhana, J.; Sharbeen, G.; Phillips, P. A.; Kilian, K. A.
Advanced Biology 5 (6) :e2000525, 2021 10.1002/adbi.202000525
OpenAccess publication Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes
Ghoroghi, S.; Mary, B.; Larnicol, A.; Asokan, N.; Klein, A.; Osmani, N.; Busnelli, I.; Delalande, F.; Paul, N.; Halary, S.; Gros, F.; Fouillen, L.; Haeberle, A. M.; Royer, C.; Spiegelhalter, C.; Andre-Gregoire, G.; Mittelheisser, V.; Detappe, A.; Murphy, K.; Timpson, P.; Carapito, R.; Blot-Chabaud, M.; Gavard, J.; Carapito, C.; Vitale, N.; Lefebvre, O.; Goetz, J. G.; Hyenne, V.
eLife 10 :e61539, 2021 10.7554/eLife.61539