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Spatial and Temporal Control of CRISPR-Cas9-Mediated Gene Editing Delivered via a Light-Triggered Liposome System
Aksoy, Y. A.; Yang, B.; Chen, W.; Hung, T.; Kuchel, R. P.; Zammit, N. W.; Grey, S. T.; Goldys, E. M.; Deng, W.
ACS Applied Materials & Interfaces 12 (47) :52433-52444, 2020 10.1021/acsami.0c16380
Benchmarking of cell type deconvolution pipelines for transcriptomics data
Cobos, F. A.; Alquicira-Hernandez, J.; Powell, J. E.; Mestdagh, P.; De Preter, K.
Nature Communications 11 (1) :6291, 2020 10.1038/s41467-020-20288-9
PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis
Srijakotre, N.; Liu, H. J.; Nobis, M.; Man, J.; Yip, H. Y. K.; Papa, A.; Abud, H. E.; Anderson, K. I.; Welch, H. C. E.; Tiganis, T.; Timpson, P.; McLean, C. A.; Ooms, L. M.; Mitchell, C. A.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (45) :28056-28067, 2020 10.1073/pnas.2006445117
A zebrafish functional genomics model to investigate the role of human A20 variants in vivo
Cultrone, D.; Zammit, N. W.; Self, E.; Postert, B.; Han, J. Z. R.; Bailey, J.; Warren, J.; Croucher, D. R.; Kikuchi, K.; Bogdanovic, O.; Chtanova, T.; Hesselson, D.; Grey, S. T.
Scientific Reports 10 (1) :19085, 2020 10.1038/s41598-020-75917-6.
Optimizing care for younger women with hormone receptor-positive, HER2-negative metastatic breast cancer
de Boer, R.; Hui, R.; Lim, E.; Yeo, B.; Zdenkowski, N.
Asia-Pacific Journal of Clinical Oncology 16 Suppl 5 :3-14, 2020 10.1111/ajco.13461
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer
Wong, M.; Mayoh, C.; Lau, L. M. S.; Khuong-Quang, D. A.; Pinese, M.; Kumar, A.; Barahona, P.; Wilkie, E. E.; Sullivan, P.; Bowen-James, R.; Syed, M.; Martincorena, I.; Abascal, F.; Sherstyuk, A.; Bolanos, N. A.; Baber, J.; Priestley, P.; Dolman, M. E. M.; Fleuren, E. D. G.; Gauthier, M. E.; Mould, E. V. A.; Gayevskiy, V.; Gifford, A. J.; Grebert-Wade, D.; Strong, P. A.; Manouvrier, E.; Warby, M.; Thomas, D. M.; Kirk, J.; Tucker, K.; O'Brien, T.; Alvaro, F.; McCowage, G. B.; Dalla-Pozza, L.; Gottardo, N. G.; Tapp, H.; Wood, P.; Khaw, S. L.; Hansford, J. R.; Moore, A. S.; Norris, M. D.; Trahair, T. N.; Lock, R. B.; Tyrrell, V.; Haber, M.; Marshall, G. M.; Ziegler, D. S.; Ekert, P. G.; Cowley, M. J.
NATURE MEDICINE 26 (11) :1742-1753, 2020 10.1038/s41591-020-1072-4
Loss-of-Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities
Steel, D.; Zech, M.; Zhao, C.; Barwick, K. E. S.; Burke, D.; Demailly, D.; Kumar, K. R.; Zorzi, G.; Nardocci, N.; Kaiyrzhanov, R.; Wagner, M.; Iuso, A.; Berutti, R.; Skorvanek, M.; Necpal, J.; Davis, R.; Wiethoff, S.; Mankad, K.; Sudhakar, S.; Ferrini, A.; Sharma, S.; Kamsteeg, E. J.; Tijssen, M. A.; Verschuuren, C.; van Egmond, M. E.; Flowers, J. M.; McEntagart, M.; Tucci, A.; Coubes, P.; Bustos, B. I.; Gonzalez-Latapi, P.; Tisch, S.; Darveniza, P.; Gorman, K. M.; Peall, K. J.; Botzel, K.; Koch, J. C.; Kmiec, T.; Plecko, B.; Boesch, S.; Haslinger, B.; Jech, R.; Garavaglia, B.; Wood, N.; Houlden, H.; Gissen, P.; Lubbe, S. J.; Sue, C. M.; Cif, L.; Mencacci, N. E.; Anderson, G.; Kurian, M. A.; Winkelmann, J.; Genomics England Research, Consortium
ANNALS OF NEUROLOGY 88 (5) :867-877, 2020 10.1002/ana.25879
Regulation of auditory plasticity during critical periods and following hearing loss
Persic, D.; Thomas, M. E.; Pelekanos, V.; Ryugo, D. K.; Takesian, A. E.; Krumbholz, K.; Pyott, S. J.
HEARING RESEARCH 397 :107976, 2020 10.1016/j.heares.2020.107976
A Randomized Trial on the Effect of Phosphate Reduction on Vascular End Points in CKD (IMPROVE-CKD)
Toussaint, N. D.; Pedagogos, E.; Lioufas, N. M.; Elder, G. J.; Pascoe, E. M.; Badve, S. V.; Valks, A.; Block, G. A.; Boudville, N.; Cameron, J. D.; Campbell, K. L.; Chen, S. S. M.; Faull, R. J.; Holt, S. G.; Jackson, D.; Jardine, M. J.; Johnson, D. W.; Kerr, P. G.; Lau, K. K.; Hooi, L. S.; Narayan, O.; Perkovic, V.; Polkinghorne, K. R.; Pollock, C. A.; Reidlinger, D.; Robison, L.; Smith, E. R.; Walker, R. J.; Wang, A. Y. M.; Hawley, C. M.; Investigators, Improve-Ckd Trial
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 31 (11) :2653-2666, 2020 10.1681/ASN.2020040411
Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1
Kalaw, E.; Lim, M.; Kutasovic, J. R.; Sokolova, A.; Taege, L.; Johnstone, K.; Bennett, J.; Saunus, J. M.; Niland, C.; Ferguson, K.; Gresshoff, I.; Bettington, M.; Pathmanathan, N.; Tse, G. M.; Papadimos, D.; Pathmanathan, R.; Harris, G.; Yamaguchi, R.; Tan, P. H.; Fox, S.; O'Toole, S. A.; Simpson, P. T.; Lakhani, S. R.; McCart Reed, A. E.
British Journal of Cancer 123 (11) :1665-1672, 2020 10.1038/s41416-020-01065-3
Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network
Demetri, G. D.; Antonescu, C. R.; Bjerkehagen, B.; Bovee, Jvmg; Boye, K.; Chacon, M.; Dei Tos, A. P.; Desai, J.; Fletcher, J. A.; Gelderblom, H.; George, S.; Gronchi, A.; Haas, R. L.; Hindi, N.; Hohenberger, P.; Joensuu, H.; Jones, R. L.; Judson, I.; Kang, Y. K.; Kawai, A.; Lazar, A. J.; Le Cesne, A.; Maestro, R.; Maki, R. G.; Martin, J.; Patel, S.; Penault-Llorca, F.; Premanand Raut, C.; Rutkowski, P.; Safwat, A.; Sbaraglia, M.; Schaefer, I. M.; Shen, L.; Serrano, C.; Schoffski, P.; Stacchiotti, S.; Sundby Hall, K.; Tap, W. D.; Thomas, D. M.; Trent, J.; Valverde, C.; van der Graaf, W. T. A.; von Mehren, M.; Wagner, A.; Wardelmann, E.; Naito, Y.; Zalcberg, J.; Blay, J. Y.
Annals Of Oncology 31 (11) :1506-1517, 2020 10.1016/j.annonc.2020.08.2232
Friends and foes: Our evolving understanding of the link between Fbxw7 and p53 in cancer
Caldon, C.E.
NEOPLASIA 22 (11) :659-660, 2020 10.1016/j.neo.2020.07.007
Letter to the Editor: Risk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes: Findings from Prospective Real-life T1D Exchange Registry
Snaith, J. R.; Holmes-Walker, D. J.; Greenfield, J. R.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 105 (10) :e3834-e3835, 2020 10.1210/clinem/dgaa383
Energy partitioning between fat and bone mass is controlled via a hypothalamic leptin/NPY relay
Lee, N. J.; Qi, Y.; Enriquez, R. F.; Clarke, I.; Ip, C. K.; Wee, N.; Baldock, P. A.; Herzog, H.
INTERNATIONAL JOURNAL OF OBESITY 44 (10) :2149-2164, 2020 10.1038/s41366-020-0550-6
Short-term inhibition of autophagy benefits pancreatic beta-cells by augmenting ether lipids and peroxisomal function, and by countering depletion of n-3 polyunsaturated fatty acids after fat-feeding
Chu, K. Y.; Mellet, N.; Thai, L. M.; Meikle, P. J.; Biden, T. J.
Molecular Metabolism 40 :101023, 2020 10.1016/j.molmet.2020.101023
A Vagal-NTS Neural Pathway that Stimulates Feeding
Chen, J.; Cheng, M.; Wang, L.; Zhang, L.; Xu, D.; Cao, P.; Wang, F.; Herzog, H.; Song, S.; Zhan, C.
CURRENT BIOLOGY 30 (20) :3986-3998.e5, 2020 10.1016/j.cub.2020.07.084