Garvan Institute of Medical Research

Sancho-Shimizu, V.; Brodin, P.; Cobat, A.; Biggs, C.M.; Toubiana, J.; Lucas, C.L.; Henrickson, S.E.; Belot, A.; Tangye, S.G.; Milner, J.D.; Levin, M.; Abel, L.; Bogunovic, D.; Casanova, J.L.; Zhang, S.Y.

JOURNAL OF EXPERIMENTAL MEDICINE 218 (6) 2021 10.1084/jem.20210446

Association between vitamin D deficiency and exercise capacity in patients with CKD, a cross-sectional analysis

Watson, E. L.; Wilkinson, T. J.; O'Sullivan, T. F.; Baker, L. A.; Gould, D. W.; Xenophontos, S.; Graham-Brown, M.; Major, R.; Jenkinson, C.; Hewison, M.; Philp, A.; Smith, A. C.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 210 :105861, 2021 10.1016/j.jsbmb.2021.105861

Single cell transcriptome atlas of mouse mammary epithelial cells across development

Pal, B.; Chen, Y.; Milevskiy, M. J. G.; Vaillant, F.; Prokopuk, L.; Dawson, C. A.; Capaldo, B. D.; Song, X.; Jackling, F.; Timpson, P.; Lindeman, G. J.; Smyth, G. K.; Visvader, J. E.https://publications.gimr.garvan.org.au/app/

BREAST CANCER RESEARCH 23 (1) :69, 2021 10.1186/s13058-021-01445-4

Exome-based investigation of the genetic basis of human pigmentary glaucoma

van der Heide, C.; Goar, W.; Meyer, K. J.; Alward, W. L. M.; Boese, E. A.; Sears, N. C.; Roos, B. R.; Kwon, Y. H.; DeLuca, A. P.; Siggs, O. M.; Gonzaga-Jauregui, C.; Sheffield, V. C.; Wang, K.; Stone, E. M.; Mullins, R. F.; Anderson, M. G.; Fan, B. J.; Ritch, R.; Craig, J. E.; Wiggs, J. L.; Scheetz, T. E.; Fingert, J. H.

BMC Genomics 22 (1) :477, 2021 10.1186/s12864-021-07782-0

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

Samuel, M.; Fonseka, P.; Sanwlani, R.; Gangoda, L.; Chee, S. H.; Keerthikumar, S.; Spurling, A.; Chitti, S. V.; Zanker, D.; Ang, C. S.; Atukorala, I.; Kang, T.; Shahi, S.; Marzan, A. L.; Nedeva, C.; Vennin, C.; Lucas, M. C.; Cheng, L.; Herrmann, D.; Pathan, M.; Chisanga, D.; Warren, S. C.; Zhao, K.; Abraham, N.; Anand, S.; Boukouris, S.; Adda, C. G.; Jiang, L.; Shekhar, T. M.; Baschuk, N.; Hawkins, C. J.; Johnston, A. J.; Orian, J. M.; Hoogenraad, N. J.; Poon, I. K.; Hill, A. F.; Jois, M.; Timpson, P.; Parker, B. S.; Mathivanan, S.

Nature Communications 12 (1) :3950, 2021 10.1038/s41467-021-24273-8

Multidisciplinary Team Care in the Surgical Management of Pituitary Adenoma

Grayson, J. W.; Nayak, A.; Winder, M.; Jonker, B.; Alvarado, R.; Barham, H.; McCormack, A.; Harvey, R. J.

Journal of Neurological Surgery Part B-Skull Base 82 (3) :295-302, 2021 10.1055/s-0039-1700498

Prediction of short-term antidepressant response using probabilistic graphical models with replication across multiple drugs and treatment settings

Athreya, A. P.; Bruckl, T.; Binder, E. B.; John Rush, A.; Biernacka, J.; Frye, M. A.; Neavin, D.; Skime, M.; Monrad, D.; Iyer, R. K.; Mayes, T.; Trivedi, M.; Carter, R. E.; Wang, L.; Weinshilboum, R. M.; Croarkin, P. E.; Bobo, W. V.

Neuropsychopharmacology 46 (7) :1272-1282, 2021 10.1038/s41386-020-00943-x

Transcriptome analysis of islets from diabetes-resistant and diabetes-prone obese mice reveals novel gene regulatory networks involved in beta-cell compensation and failure

Chan, J. Y.; Bensellam, M.; Lin, R. C. Y.; Liang, C.; Lee, K.; Jonas, J. C.; Laybutt, D. R.

FASEB JOURNAL 35 (6) :e21608, 2021 10.1096/fj.202100009R

Genome-based therapeutic interventions for beta-type hemoglobinopathies

Karamperis, K.; Tsoumpeli, M. T.; Kounelis, F.; Koromina, M.; Mitropoulou, C.; Moutinho, C.; Patrinos, G. P.

Human Genomics 15 (1) :32, 2021 10.1186/s40246-021-00329-0

Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs

Wang, Q. S.; Kelley, D. R.; Ulirsch, J.; Kanai, M.; Sadhuka, S.; Cui, R.; Albors, C.; Cheng, N.; Okada, Y.; Biobank Japan, Project; Aguet, F.; Ardlie, K. G.; MacArthur, D. G.; Finucane, H. K.

Nature Communications 12 (1) :3394, 2021 10.1038/s41467-021-23134-8

Editorial: The Phylogenetic History of Hypothalamic Neuromodulators

Bittencourt, J. C.; Diniz, G. B.; Lovejoy, D. A.; Herzog, H.

Frontiers in Neuroscience 15 :712448, 2021 10.3389/fnins.2021.712448

Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish

Buono, L.; Corbacho, J.; Naranjo, S.; Almuedo-Castillo, M.; Moreno-Marmol, T.; de la Cerda, B.; Sanbria-Reinoso, E.; Polvillo, R.; Diaz-Corrales, F. J.; Bogdanovic, O.; Bovolenta, P.; Martinez-Morales, J. R.

Nature Communications 12 (1) :3866, 2021 10.1038/s41467-021-24169-7

Intronic Haplotypes in GBA Modify Age at Diagnosis of Parkinson's: Replication in a Subgroup

O'Sullivan, J. M.; den Heijer, J. M.; Groeneveld, G. J.; Cooper, A. A.

MOVEMENT DISORDERS 36 (6) :1468-1470, 2021 10.1002/mds.28620

Potent PDE4 inhibitor activates AMPK and Sirt1 to induce mitochondrial biogenesis

Park, S. J.; Ahmad, F.; Bahde, R. J.; Philp, A.; Kim, J.; Huang, T.; Kim, M. K.; Trenkle, W. C.; Chung, J. H.

PLoS One 16 (6) :e0253269, 2021 10.1371/journal.pone.0253269

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images

Currant, H.; Hysi, P.; Fitzgerald, T. W.; Gharahkhani, P.; Bonnemaijer, P. W. M.; Senabouth, A.; Hewitt, A. W.; Eye, U. K. Biobank; Vision, Consortium; International Glaucoma Genetics, Consortium; Atan, D.; Aung, T.; Charng, J.; Choquet, H.; Craig, J.; Khaw, P. T.; Klaver, C. C. W.; Kubo, M.; Ong, J. S.; Pasquale, L. R.; Reisman, C. A.; Daniszewski, M.; Powell, J. E.; Pebay, A.; Simcoe, M. J.; Thiadens, Aahj; van Duijn, C. M.; Yazar, S.; Jorgenson, E.; MacGregor, S.; Hammond, C. J.; Mackey, D. A.; Wiggs, J. L.; Foster, P. J.; Patel, P. J.; Birney, E.; Khawaja, A. P.

PLoS Genetics 17 (5) :e1009497, 2021 10.1371/journal.pgen.1009497

Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP

Guo, G.; Papanicolaou, M.; Demarais, N. J.; Wang, Z.; Schey, K. L.; Timpson, P.; Cox, T. R.; Grey, A. C.

Nature Communications 12 (1) :3241, 2021 10.1038/s41467-021-23461-w