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39 items matching your search terms.
Osteoclast Recycling and the Rebound Phenomenon Following Denosumab Discontinuation
Kim, A. S.; Girgis, C. M.; McDonald, M. M.
Current Osteoporosis Reports 20 (6) :505-515, 2022 10.1007/s11914-022-00756-5
New Insights Into Osteoclast Biology
McDonald, M. M.; Kim, A. S.; Mulholland, B. S.; Rauner, M.
JOURNAL OF BONE AND MINERAL RESEARCH PLUS 5 (9) :e10539, 2021 10.1002/jbm4.10539
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
Youlten, S. E.; Kemp, J. P.; Logan, J. G.; Ghirardello, E. J.; Sergio, C. M.; Dack, M. R. G.; Guilfoyle, S. E.; Leitch, V. D.; Butterfield, N. C.; Komla-Ebri, D.; Chai, R. C.; Corr, A. P.; Smith, J. T.; Mohanty, S. T.; Morris, J. A.; McDonald, M. M.; Quinn, J. M. W.; McGlade, A. R.; Bartonicek, N.; Jansson, M.; Hatzikotoulas, K.; Irving, M. D.; Beleza-Meireles, A.; Rivadeneira, F.; Duncan, E.; Richards, J. B.; Adams, D. J.; Lelliott, C. J.; Brink, R.; Phan, T. G.; Eisman, J. A.; Evans, D. M.; Zeggini, E.; Baldock, P. A.; Bassett, J. H. D.; Williams, G. R.; Croucher, P. I.
Nature Communications 12 (1) :2444, 2021 10.1038/s41467-021-22517-1
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
McDonald, M. M.; Khoo, W. H.; Ng, P. Y.; Xiao, Y.; Zamerli, J.; Thatcher, P.; Kyaw, W.; Pathmanandavel, K.; Grootveld, A. K.; Moran, I.; Butt, D.; Nguyen, A.; Corr, A.; Warren, S.; Biro, M.; Butterfield, N. C.; Guilfoyle, S. E.; Komla-Ebri, D.; Dack, M. R. G.; Dewhurst, H. F.; Logan, J. G.; Li, Y.; Mohanty, S. T.; Byrne, N.; Terry, R. L.; Simic, M. K.; Chai, R.; Quinn, J. M. W.; Youlten, S. E.; Pettitt, J. A.; Abi-Hanna, D.; Jain, R.; Weninger, W.; Lundberg, M.; Sun, S.; Ebetino, F. H.; Timpson, P.; Lee, W. M.; Baldock, P. A.; Rogers, M. J.; Brink, R.; Williams, G. R.; Bassett, J. H. D.; Kemp, J. P.; Pavlos, N. J.; Croucher, P. I.; Phan, T. G.
CELL 184 (5) :1330-1347 e13, 2021 10.1016/j.cell.2021.02.002
Myeloma-Modified Adipocytes Exhibit Metabolic Dysfunction and a Senescence-Associated Secretory Phenotype
Fairfield, H.; Dudakovic, A.; Khatib, C. M.; Farrell, M.; Costa, S.; Falank, C.; Hinge, M.; Murphy, C. S.; DeMambro, V.; Pettitt, J. A.; Lary, C. W.; Driscoll, H. E.; McDonald, M. M.; Kassem, M.; Rosen, C.; Andersen, T. L.; van Wijnen, A. J.; Jafari, A.; Reagan, M. R.
CANCER RESEARCH 81 (3) :634-647, 2021 10.1158/0008-5472.CAN-20-1088
Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone
Owen, K. L.; Gearing, L. J.; Zanker, D. J.; Brockwell, N. K.; Khoo, W. H.; Roden, D. L.; Cmero, M.; Mangiola, S.; Hong, M. K.; Spurling, A. J.; McDonald, M.; Chan, C. L.; Pasam, A.; Lyons, R. J.; Duivenvoorden, H. M.; Ryan, A.; Butler, L. M.; Mariadason, J. M.; Giang Phan, T.; Hayes, V. M.; Sandhu, S.; Swarbrick, A.; Corcoran, N. M.; Hertzog, P. J.; Croucher, P. I.; Hovens, C.; Parker, B. S.
EMBO REPORTS 21 (6) :e50162, 2020 10.15252/embr.202050162
Elevated Bone Hardness Under Denosumab Treatment, With Persisting Lower Osteocyte Viability During Discontinuation
Jahn-Rickert, K.; Wolfel, E. M.; Jobke, B.; Riedel, C.; Hellmich, M.; Werner, M.; McDonald, M. M.; Busse, B.
Frontiers in Endocrinology 11 :250, 2020 10.3389/fendo.2020.00250
Cancer Cell Dormancy in Metastasis
Summers, M. A.; McDonald, M. M.; Croucher, P. I.
Cold Spring Harbor Perspectives in Medicine 10 (4) 2020 10.1101/cshperspect.a037556
Pretreatment with Pamidronate Decreases Bone Formation but Increases Callus Bone Volume in a Rat Closed Fracture Model
Morse, A.; McDonald, M. M.; Mikulec, K.; Schindeler, A.; Munns, C. F.; Little, D. G.
CALCIFIED TISSUE INTERNATIONAL 106 (2) :172-179, 2020 10.1007/s00223-019-00615-z
Increased anabolic bone response in Dkk1 KO mice following tibial compressive loading
Morse, A.; Ko, F.; McDonald, M. M.; Lee, L.; Schindeler, A.; van der Meulen, M. C. H.; Little, D. G.
BONE 131 :115054, 2020 10.1016/j.bone.2019.115054
Loss of the Vitamin D Receptor in Human Breast Cancer Cells Promotes Epithelial to Mesenchymal Cell Transition and Skeletal Colonization
Horas, K.; Zheng, Y.; Fong-Yee, C.; Macfarlane, E.; Manibo, J.; Chen, Y.; Qiao, J.; Gao, M.; Haydar, N.; McDonald, M. M.; Croucher, P. I.; Zhou, H.; Seibel, M. J.
JOURNAL OF BONE AND MINERAL RESEARCH 34 (9) :1721-1732, 2019 10.1002/jbmr.3744
A Niche-Dependent Myeloid Transcriptome Signature Defines Dormant Myeloma Cells
Khoo, W. H.; Ledergor, G.; Weiner, A.; Roden, D. L.; Terry, R. L.; McDonald, M. M.; Chai, R. C.; De Veirman, K.; Owen, K. L.; Opperman, K. S.; Vandyke, K.; Clark, J. R.; Seckinger, A.; Kovacic, N.; Nguyen, A.; Mohanty, S. T.; Pettitt, J. A.; Xiao, Y.; Corr, A. P.; Seeliger, C.; Novotny, M.; Lasken, R. S.; Nguyen, T. V.; Oyajobi, B. O.; Aftab, D.; Swarbrick, A.; Parker, B.; Hewett, D. R.; Hose, D.; Vanderkerken, K.; Zannettino, A. C. W.; Amit, I.; Phan, T. G.; Croucher, P. I.
Blood 134 (1) :30-43, 2019 10.1182/blood.2018880930
OpenAccess publication Tumor cell dormancy and reactivation in bone: skeletal biology and therapeutic opportunities
Byrne, N.M., Summers, M.A. and McDonald, M.M.
JOURNAL OF BONE AND MINERAL RESEARCH PLUS 3 (3) :e10125, 2019 10.1002/jbm4.10125
Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume
Morse, A.; Cheng, T. L.; Schindeler, A.; McDonald, M. M.; Mohanty, S. T.; Kneissel, M.; Kramer, I.; Little, D. G.
CALCIFIED TISSUE INTERNATIONAL 103 (3) :298-310, 2018 10.1007/s00223-018-0420-6
Sclerostin antibody enhances bone formation in a rat model of distraction osteogenesis
McDonald, M. M.; Morse, A.; Birke, O.; Yu, N. Y. C.; Mikulec, K.; Peacock, L.; Schindeler, A.; Liu, M.; Ke, H. Z.; Little, D. G.
JOURNAL OF ORTHOPAEDIC RESEARCH 36 (4) :1106-1113, 2018 10.1002/jor.23726
Sclerostin Antibody Augments the Anabolic Bone Formation Response in a Mouse Model of Mechanical Tibial Loading
Morse, A.; Schindeler, A.; McDonald, M. M.; Kneissel, M.; Kramer, I.; Little, D. G.
JOURNAL OF BONE AND MINERAL RESEARCH 33 (3) :486-498, 2018 10.1002/jbmr.3330