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85 items matching your search terms.
OpenAccess publication Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity
Wu, L. E. ; Samocha-Bonet, D. ; Whitworth, P. T. ; Fazakerley, D. J. ; Turner, N. ; Biden, T. J. ; James, D. E. ; Cantley, J.;
Molecular Metabolism 3 (4) :465-73, 2014
OpenAccess publication Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells
McCloy, R. A. ; Shelley, E. J. ; Roberts, C. G. ; Boslem, E. ; Biden, T. J. ; Nicholson, R. I. ; Gee, J. M. ; Sutherland, R. L. ; Musgrove, E. A. ; Burgess, A. ; Butt, A. J.;
British Journal of Cancer 109 (12) :3034-41, 2013
OpenAccess publication Alteration of Endoplasmic Reticulum Lipid Rafts Contributes to Lipotoxicity in Pancreatic beta-Cells
Boslem, E.; Weir, J. M.; Macintosh, G.; Sue, N.; Cantley, J.; Meikle, P. J.; Biden, T. J.;
JOURNAL OF BIOLOGICAL CHEMISTRY 288 (37) :26569-82, 2013
OpenAccess publication Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in beta-cell gene expression and progression to diabetes
Chan, J. Y.; Luzuriaga, J.; Bensellam, M.; Biden, T. J.; Laybutt, D. R.
DIABETES 62 (5) :1557-68, 2013 10.2337/db12-0701
OpenAccess publication Sweet and sour beta-cells: ROS and Hif1alpha induce warburg-like lactate production during type 2 diabetes
Cantley, J.; Biden, T. J.;
DIABETES 62 (6) :1823-5, 2013
OpenAccess publication Cross-talk between the unfolded protein response and nuclear factor-kappaB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets
Chan, J. Y.; Biden, T. J.; Laybutt, D. R.
CELL DEATH AND DIFFERENTIATION 55 (11) :2999-3009, 2012 10.1007/s00125-012-2657-3
OpenAccess publication G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1
Ferdaoussi, M.; Bergeron, V.; Zarrouki, B.; Kolic, J.; Cantley, J.; Fielitz, J.; Olson, E. N.; Prentki, M.; Biden, T.; MacDonald, P. E.; Poitout, V.;
DIABETOLOGIA 55 (10) :2682-92, 2012
OpenAccess publication Roles of ceramide and sphingolipids in pancreatic beta-cell function and dysfunction
Boslem, E.; Meikle, P. J.; Biden, T. J.;
Islets 4 (3) :177-87, 2012
OpenAccess publication Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice
Raddatz, K.; Turner, N.; Frangioudakis, G.; Liao, B. M.; Pedersen, D. J.; Cantley, J.; Wilks, D.; Preston, E.; Hegarty, B. D.; Leitges, M.; Raftery, M. J.; Biden, T. J.; Schmitz-Peiffer, C.
DIABETOLOGIA 54 (6) :1447-56, 2011
OpenAccess publication Deletion of protein kinase Cdelta in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo
Cantley, J.; Boslem, E.; Laybutt, D.R.; Cordery, D.; Pearson, G.; Carpenter, L.; Leitges, M.; Biden, T.J.:
DIABETOLOGIA 54 (2) :380-9, 2011 10.1007/s00125-010-1962-y
OpenAccess publication Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells
Chan, J. Y.; Cooney, G. J.; Biden, T. J.; Laybutt, D. R.;
DIABETOLOGIA 54 (7) :1766-76, 2011
OpenAccess publication A lipidomic screen of palmitate-treated MIN6 beta-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking
Boslem, E.; MacIntosh, G.; Preston, A. M.; Bartley, C.; Busch, A. K.; Fuller, M.; Laybutt, D. R.; Meikle, P. J.; Biden, T. J.;
BIOCHEMICAL JOURNAL 435 (1) :267-76, 2011
OpenAccess publication Targeting triglyceride/fatty acid cycling in beta cells as a therapy for augmenting glucose-stimulated insulin secretion
Cantley, J.; Biden, T.J.;
Islets 2 (2) :127-29, 2010
OpenAccess publication PKCdelta blues for the beta-cell
Schmitz-Peiffer, C.; Biden, T. J.;
DIABETES 59 (1) :1-3, 2010
OpenAccess publication Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload
Preston, A. M.; Gurisik, E.; Bartley, C.; Laybutt, D. R.; Biden, T. J.;
DIABETOLOGIA 52 (11) :2369-2373, 2009
OpenAccess publication Diverse roles for protein kinase C delta and protein kinase C epsilon in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C delta
Frangioudakis, G.; Burchfield, J.G.; Narasimhan, S.; Cooney, G.J.; Leitges, M.; Biden, T.J.; Schmitz-Peiffer, C.:
DIABETOLOGIA 52 (12) :2616, 2009