Publications

85 items matching your search terms.

Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

Wu, L. E. ; Samocha-Bonet, D. ; Whitworth, P. T. ; Fazakerley, D. J. ; Turner, N. ; Biden, T. J. ; James, D. E. ; Cantley, J.;

Molecular Metabolism 3 (4) :465-73, 2014

Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells

McCloy, R. A. ; Shelley, E. J. ; Roberts, C. G. ; Boslem, E. ; Biden, T. J. ; Nicholson, R. I. ; Gee, J. M. ; Sutherland, R. L. ; Musgrove, E. A. ; Burgess, A. ; Butt, A. J.;

British Journal of Cancer 109 (12) :3034-41, 2013

Alteration of Endoplasmic Reticulum Lipid Rafts Contributes to Lipotoxicity in Pancreatic beta-Cells

Boslem, E.; Weir, J. M.; Macintosh, G.; Sue, N.; Cantley, J.; Meikle, P. J.; Biden, T. J.;

JOURNAL OF BIOLOGICAL CHEMISTRY 288 (37) :26569-82, 2013

Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in beta-cell gene expression and progression to diabetes

Chan, J. Y.; Luzuriaga, J.; Bensellam, M.; Biden, T. J.; Laybutt, D. R.

DIABETES 62 (5) :1557-68, 2013 10.2337/db12-0701

Sweet and sour beta-cells: ROS and Hif1alpha induce warburg-like lactate production during type 2 diabetes

Cantley, J.; Biden, T. J.;

DIABETES 62 (6) :1823-5, 2013

Cross-talk between the unfolded protein response and nuclear factor-kappaB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets

Chan, J. Y.; Biden, T. J.; Laybutt, D. R.

CELL DEATH AND DIFFERENTIATION 55 (11) :2999-3009, 2012 10.1007/s00125-012-2657-3

G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1

Ferdaoussi, M.; Bergeron, V.; Zarrouki, B.; Kolic, J.; Cantley, J.; Fielitz, J.; Olson, E. N.; Prentki, M.; Biden, T.; MacDonald, P. E.; Poitout, V.;

DIABETOLOGIA 55 (10) :2682-92, 2012

Roles of ceramide and sphingolipids in pancreatic beta-cell function and dysfunction

Boslem, E.; Meikle, P. J.; Biden, T. J.;

Islets 4 (3) :177-87, 2012

Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice

Raddatz, K.; Turner, N.; Frangioudakis, G.; Liao, B. M.; Pedersen, D. J.; Cantley, J.; Wilks, D.; Preston, E.; Hegarty, B. D.; Leitges, M.; Raftery, M. J.; Biden, T. J.; Schmitz-Peiffer, C.

DIABETOLOGIA 54 (6) :1447-56, 2011

Deletion of protein kinase Cdelta in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo

Cantley, J.; Boslem, E.; Laybutt, D.R.; Cordery, D.; Pearson, G.; Carpenter, L.; Leitges, M.; Biden, T.J.:

DIABETOLOGIA 54 (2) :380-9, 2011 10.1007/s00125-010-1962-y

Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells

Chan, J. Y.; Cooney, G. J.; Biden, T. J.; Laybutt, D. R.;

DIABETOLOGIA 54 (7) :1766-76, 2011

A lipidomic screen of palmitate-treated MIN6 beta-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking

Boslem, E.; MacIntosh, G.; Preston, A. M.; Bartley, C.; Busch, A. K.; Fuller, M.; Laybutt, D. R.; Meikle, P. J.; Biden, T. J.;

BIOCHEMICAL JOURNAL 435 (1) :267-76, 2011

Targeting triglyceride/fatty acid cycling in beta cells as a therapy for augmenting glucose-stimulated insulin secretion

Cantley, J.; Biden, T.J.;

Islets 2 (2) :127-29, 2010

PKCdelta blues for the beta-cell

Schmitz-Peiffer, C.; Biden, T. J.;

DIABETES 59 (1) :1-3, 2010

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload

Preston, A. M.; Gurisik, E.; Bartley, C.; Laybutt, D. R.; Biden, T. J.;

DIABETOLOGIA 52 (11) :2369-2373, 2009

Diverse roles for protein kinase C delta and protein kinase C epsilon in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C delta

Frangioudakis, G.; Burchfield, J.G.; Narasimhan, S.; Cooney, G.J.; Leitges, M.; Biden, T.J.; Schmitz-Peiffer, C.:

DIABETOLOGIA 52 (12) :2616, 2009