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224 items matching your search terms.
OpenAccess publication Insulin resistance is a cellular antioxidant defense mechanism
Hoehn, K. L.; Salmon, A. B.; Hohnen-Behrens, C.; Turner, N.; Hoy, A. J.; Maghzal, G. J.; Stocker, R.; Van Remmen, H.; Kraegen, E. W.; Cooney, G. J.; Richardson, A. R.; James, D. E.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106 (42) :17787-92, 2009 0902380106 [pii] 10.1073/pnas.0902380106
OpenAccess publication Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation
Hoy, A. J.; Brandon, A. E.; Turner, N.; Watt, M. J.; Bruce, C. R.; Cooney, G. J.; Kraegen, E. W.;
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 297 (1) :E67-75, 2009
OpenAccess publication Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice
Hui, X.; Zhu, W.; Wang, Y.; Lam, K. S.; Zhang, J.; Wu, D.; Kraegen, E. W.; Li, Y.; Xu, A.
JOURNAL OF BIOLOGICAL CHEMISTRY 284 (21) :14050-7, 2009 M109.001107 [pii] 10.1074/jbc.M109.001107
OpenAccess publication Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance
Bruce, C. R.; Hoy, A. J.; Turner, N.; Watt, M. J.; Allen, T. L.; Carpenter, K.; Cooney, G. J.; Febbraio, M. A.; Kraegen, E. W.;
DIABETES 58 (3) :550-8, 2009
OpenAccess publication Insulin resistance and fuel homeostasis: the role of AMP-activated protein kinase
Hegarty, B. D.; Turner, N.; Cooney, G. J.; Kraegen, E. W.;
Acta Physiologica 196 (1) :129-45, 2009
OpenAccess publication Fat partitioning and insulin sensitivity: robbing Peter to pay Paul?
Watt, M. J.; Kraegen, E. W.;
DIABETES 58 (1) :16-7, 2009
OpenAccess publication Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids
Turner, N.; Hariharan, K.; TidAng, J.; Frangioudakis, G.; Beale, S. M.; Wright, L. E.; Zeng, X. Y.; Leslie, S. J.; Li, J. Y.; Kraegen, E. W.; Cooney, G. J.; Ye, J. M.;
DIABETES 58 (11) :2547-54, 2009
OpenAccess publication APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice
Cheng, K. K.; Iglesias, M. A.; Lam, K. S.; Wang, Y.; Sweeney, G.; Zhu, W.; Vanhoutte, P. M.; Kraegen, E. W.; Xu, A.;
Cell Metabolism 9 (5) :417-27, 2009
OpenAccess publication AMP-activated protein kinase and muscle insulin resistance
Kraegen, E. W.; Bruce, C.; Hegarty, B. D.; Ye, J. M.; Turner, N.; Cooney, G.;
Frontiers in Bioscience-Landmark 14 :4658-72, 2009
OpenAccess publication Evidence that {alpha}-Calcitonin Gene-Related Peptide Is a Neurohormone that Controls Systemic Lipid Availability and Utilization
Danaher, R. N.;Loomes, K. M.;Leonard, B. L.;Whiting, L.;Hay, D. L.;Xu, L. Y.;Kraegen, E. W.;Phillips, A. R.;Cooper, G. J. :
ENDOCRINOLOGY 149 (1) :154-60, 2008
OpenAccess publication Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action
Turner, N.;Li, J. Y.;Gosby, A.;To, S. W.;Cheng, Z.;Miyoshi, H.;Taketo, M. M.;Cooney, G. J.;Kraegen, E. W.;James, D. E.;Hu, L. H.;Li, J.;Ye, J. M. :
DIABETES 57 (5) :1414-8, 2008
OpenAccess publication Free fatty acids and skeletal muscle insulin resistance
Kraegen, E. W.;Cooney, G. J. :
CURRENT OPINION IN LIPIDOLOGY 19 (3) :235-41, 2008
OpenAccess publication Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness
Watt, M. J.;van Denderen, B. J.;Castelli, L. A.;Bruce, C. R.;Hoy, A. J.;Kraegen, E. W.;Macaulay, L.;Kemp, B. E. :
MOLECULAR ENDOCRINOLOGY 22 (5) :1200-12, 2008
OpenAccess publication Muscle insulin resistance: a case of fat overconsumption, not mitochondrial dysfunction
Kraegen, E. W.;Cooney, G. J.;Turner, N. :
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105 (22) :7627-8, 2008
OpenAccess publication Local activation of the I{kappa}K-NF-{kappa}B pathway in muscle does not cause insulin resistance
Polkinghorne, E.;Lau, Q.;Cooney, G. J.;Kraegen, E. W.;Cleasby, M. E. :
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 294 (2) :E316-E325, 2008
OpenAccess publication Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification
Bruce, C. R.;Brolin, C.;Turner, N.;Cleasby, M. E.;van der Leij, F. R.;Cooney, G. J.;Kraegen, E. W. :
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 292 (4) :E1231-7, 2007