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93 items matching your search terms.
OpenAccess publication Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
Cazet, A. S.; Hui, M. N.; Elsworth, B. L.; Wu, S. Z.; Roden, D.; Chan, C. L.; Skhinas, J. N.; Collot, R.; Yang, J.; Harvey, K.; Johan, M. Z.; Cooper, C.; Nair, R.; Herrmann, D.; McFarland, A.; Deng, N.; Ruiz-Borrego, M.; Rojo, F.; Trigo, J. M.; Bezares, S.; Caballero, R.; Lim, E.; Timpson, P.; O'Toole, S.; Watkins, D. N.; Cox, T. R.; Samuel, M. S.; Martin, M.; Swarbrick, A.
Nature Communications 9 (1) :2897, 2018 10.1038/s41467-018-05220-6
Fluorescent in situ hybridization in surgical pathology practice
Gupta, R.; Cooper, W. A.; Selinger, C.; Mahar, A.; Anderson, L.; Buckland, M. E.; O'Toole, S. A.
Advances in Anatomic Pathology 25 (4) :223-237, 2018 10.1097/pap.0000000000000194
OpenAccess publication Tumor PIK3CA genotype and prognosis in early-stage breast cancer: a pooled analysis of individual patient data
Zardavas, D.; Te Marvelde, L.; Milne, R. L.; Fumagalli, D.; Fountzilas, G.; Kotoula, V.; Razis, E.; Papaxoinis, G.; Joensuu, H.; Moynahan, M. E.; Hennessy, B. T.; Bieche, I.; Saal, L. H.; Stal, O.; Iacopetta, B.; Jensen, J. D.; O'Toole, S.; Lopez-Knowles, E.; Barbaraeschi, M.; Noguchi, S.; Azim, H. A., Jr.; Lerma, E.; Bachelot, T.; Wang, Q.; Perez-Tenorio, G.; Can de Velde, C. J. H.; Rea, D. W.; Sabine, V.; Bartlett, J. M. S.; Sotiriou, C.; Michiels, S.; Loi, S.
JOURNAL OF CLINICAL ONCOLOGY 36 (10) :981-990, 2018 10.1200/JCO.2017.74.8301
The magnitude of androgen receptor positivity in breast cancer is critical for reliable prediction of disease outcome
Ricciardelli, C.; Bianco-Miotto, T.; Jindal, S.; Butler, L. M.; Leung, S.; McNeil, C. M.; O'Toole, S. A.; Ebrahimie, E.; Millar, E. K. A.; Sakko, A. J.; Ruiz, A. I.; Vowler, S. L.; Huntsman, D. G.; Birrell, S. N.; Sutherland, R. L.; Palmieri, C.; Hickey, T. E.; Tilley, W. D.
CLINICAL CANCER RESEARCH 24 (10) :2328-2341, 2018 10.1158/1078-0432.CCR-17-1199
Analysis of clinically relevant somatic mutations in high-risk head and neck cutaneous squamous cell carcinoma
Zilberg, C.; Lee, M. W.; Yu, B.; Ashford, B.; Kraitsek, S.; Ranson, M.; Shannon, K.; Cowley, M.; Iyer, N. G.; Palme, C. E.; Ch'ng, S.; Low, T. H.; O'Toole, S.; Clark, J. R.; Gupta, R.
MODERN PATHOLOGY 31 (2) :275-287, 2018 10.1038/modpathol.2017.128
miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense
Pajic, M.; Froio, D.; Daly, S.; Doculara, L.; Millar, E.; Graham, P. H.; Drury, A.; Steinmann, A.; de Bock, C. E.; Boulghourjian, A.; Zaratzian, A.; Carroll, S.; Toohey, J.; O'Toole, S. A.; Harris, A. L.; Buffa, F. M.; Gee, H. E.; Hollway, G. E.; Molloy, T. J.
CANCER RESEARCH 78 (2) :501-515, 2018 10.1158/0008-5472.CAN-16-3105
Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion
Duivenvoorden, H. M.; Rautela, J.; Edgington-Mitchell, L. E.; Spurling, A.; Greening, D. W.; Nowell, C. J.; Molloy, T. J.; Robbins, E.; Brockwell, N. K.; Lee, C. S.; Chen, M.; Holliday, A.; Selinger, C. I.; Hu, M.; Britt, K. L.; Stroud, D. A.; Bogyo, M.; Moller, A.; Polyak, K.; Sloane, B. F.; O'Toole, S. A.; Parker, B. S.
JOURNAL OF PATHOLOGY 243 (4) :496-509, 2017 10.1002/path.4990
OpenAccess publication Andy's Algorithms: new automated digital image analysis pipelines for FIJI
Law, A. M. K.; Yin, J. X. M.; Castillo, L.; Young, A. I. J.; Piggin, C.; Rogers, S.; Caldon, C. E.; Burgess, A.; Millar, E. K. A.; O'Toole, S. A.; Gallego-Ortega, D.; Ormandy, C. J.; Oakes, S. R.
Scientific Reports 7 (1) :15717, 2017 10.1038/s41598-017-15885-6
Assessing tumor-infiltrating lymphocytes in solid tumors: A practical review for pathologists and proposal for a standardized method from the International Immunooncology Biomarkers Working Group: Part 1: Assessing the host immune response, TILs in invasive breast carcinoma and ductal carcinoma in situ, metastatic tumor deposits and areas for further research
Hendry, S.; Salgado, R.; Gevaert, T.; Russell, P. A.; John, T.; Thapa, B.; Christie, M.; van de Vijver, K.; Estrada, M. V.; Gonzalez-Ericsson, P. I.; Sanders, M.; Solomon, B.; Solinas, C.; Van den Eynden, Gggm; Allory, Y.; Preusser, M.; Hainfellner, J.; Pruneri, G.; Vingiani, A.; Demaria, S.; Symmans, F.; Nuciforo, P.; Comerma, L.; Thompson, E. A.; Lakhani, S.; Kim, S. R.; Schnitt, S.; Colpaert, C.; Sotiriou, C.; Scherer, S. J.; Ignatiadis, M.; Badve, S.; Pierce, R. H.; Viale, G.; Sirtaine, N.; Penault-Llorca, F.; Sugie, T.; Fineberg, S.; Paik, S.; Srinivasan, A.; Richardson, A.; Wang, Y.; Chmielik, E.; Brock, J.; Johnson, D. B.; Balko, J.; Wienert, S.; Bossuyt, V.; Michiels, S.; Ternes, N.; Burchardi, N.; Luen, S. J.; Savas, P.; Klauschen, F.; Watson, P. H.; Nelson, B. H.; Criscitiello, C.; O'Toole, S.; Larsimont, D.; de Wind, R.; Curigliano, G.; Andre, F.; Lacroix-Triki, M.; van de Vijver, M.; Rojo, F.; Floris, G.; Bedri, S.; Sparano, J.; Rimm, D.; Nielsen, T.; Kos, Z.; Hewitt, S.; Singh, B.; Farshid, G.; Loibl, S.; Allison, K. H.; Tung, N.; Adams, S.; Willard-Gallo, K.; Horlings, H. M.; Gandhi, L.; Moreira, A.; Hirsch, F.; Dieci, M. V.; Urbanowicz, M.; Brcic, I.; Korski, K.; Gaire, F.; Koeppen, H.; Lo, A.; Giltnane, J.; Rebelatto, M. C.; Steele, K. E.; Zha, J.; Emancipator, K.; Juco, J. W.; Denkert, C.; Reis-Filho, J.; Loi, S.; Fox, S. B.
Advances in Anatomic Pathology 24 (5) :235-251, 2017 10.1097/PAP.0000000000000162
Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors
Hendry, S.; Salgado, R.; Gevaert, T.; Russell, P. A.; John, T.; Thapa, B.; Christie, M.; van de Vijver, K.; Estrada, M. V.; Gonzalez-Ericsson, P. I.; Sanders, M.; Solomon, B.; Solinas, C.; Van den Eynden, Gggm; Allory, Y.; Preusser, M.; Hainfellner, J.; Pruneri, G.; Vingiani, A.; Demaria, S.; Symmans, F.; Nuciforo, P.; Comerma, L.; Thompson, E. A.; Lakhani, S.; Kim, S. R.; Schnitt, S.; Colpaert, C.; Sotiriou, C.; Scherer, S. J.; Ignatiadis, M.; Badve, S.; Pierce, R. H.; Viale, G.; Sirtaine, N.; Penault-Llorca, F.; Sugie, T.; Fineberg, S.; Paik, S.; Srinivasan, A.; Richardson, A.; Wang, Y.; Chmielik, E.; Brock, J.; Johnson, D. B.; Balko, J.; Wienert, S.; Bossuyt, V.; Michiels, S.; Ternes, N.; Burchardi, N.; Luen, S. J.; Savas, P.; Klauschen, F.; Watson, P. H.; Nelson, B. H.; Criscitiello, C.; O'Toole, S.; Larsimont, D.; de Wind, R.; Curigliano, G.; Andre, F.; Lacroix-Triki, M.; van de Vijver, M.; Rojo, F.; Floris, G.; Bedri, S.; Sparano, J.; Rimm, D.; Nielsen, T.; Kos, Z.; Hewitt, S.; Singh, B.; Farshid, G.; Loibl, S.; Allison, K. H.; Tung, N.; Adams, S.; Willard-Gallo, K.; Horlings, H. M.; Gandhi, L.; Moreira, A.; Hirsch, F.; Dieci, M. V.; Urbanowicz, M.; Brcic, I.; Korski, K.; Gaire, F.; Koeppen, H.; Lo, A.; Giltnane, J.; Rebelatto, M. C.; Steele, K. E.; Zha, J.; Emancipator, K.; Juco, J. W.; Denkert, C.; Reis-Filho, J.; Loi, S.; Fox, S. B.
Advances in Anatomic Pathology 24 (6) :311-335, 2017 10.1097/PAP.0000000000000161
Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer
Pang, J. B.; Savas, P.; Fellowes, A. P.; Mir Arnau, G.; Kader, T.; Vedururu, R.; Hewitt, C.; Takano, E. A.; Byrne, D. J.; Choong, D. Y.; Millar, E. K.; Lee, C. S.; O'Toole, S. A.; Lakhani, S. R.; Cummings, M. C.; Mann, G. B.; Campbell, I. G.; Dobrovic, A.; Loi, S.; Gorringe, K. L.; Fox, S. B.
MODERN PATHOLOGY 30 (7) :952-963, 2017 10.1038/modpathol.2017.21
OpenAccess publication LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness
Pang, J. B.; Molania, R.; Chand, A.; Knower, K.; Takano, E. A.; Byrne, D. J.; Mikeska, T.; Millar, E. K. A.; Lee, C. S.; O'Toole, S. A.; Clyne, C.; Gorringe, K. L.; Dobrovic, A.; Fox, S. B.
Oncotarget 8 (48) :83626-83636, 2017 10.18632/oncotarget.18886
Somatic mutations in salivary duct carcinoma and potential therapeutic targets
Khoo, T. K.; Yu, B.; Smith, J. A.; Clarke, A. J.; Luk, P. P.; Selinger, C. I.; Mahon, K. L.; Kraitsek, S.; Palme, C.; Boyer, M. J.; Dinger, M. E.; Cowley, M. J.; O'Toole, S. A.; Clark, J. R.; Gupta, R.
Oncotarget 8 (44) :75893-75903, 2017 10.18632/oncotarget.18173
OpenAccess publication The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma
Coulson, R.; Liew, S. H.; Connelly, A. A.; Yee, N. S.; Deb, S.; Kumar, B.; Vargas, A. C.; O'Toole, S. A.; Parslow, A. C.; Poh, A.; Putoczki, T.; Morrow, R. J.; Alorro, M.; Lazarus, K. A.; Yeap, E. F. W.; Walton, K. L.; Harrison, C. A.; Hannan, N. J.; George, A. J.; Clyne, C. D.; Ernst, M.; Allen, A. M.; Chand, A. L.
Oncotarget 8 (12) :18640-18656, 2017 10.18632/oncotarget.15553
Screening for ROS1 gene rearrangements in non-small-cell lung cancers using immunohistochemistry with FISH confirmation is an effective method to identify this rare target
Selinger, C. I.; Li, B. T.; Pavlakis, N.; Links, M.; Gill, A. J.; Lee, A.; Clarke, S.; Tran, T. N.; Lum, T.; Yip, P. Y.; Horvath, L.; Yu, B.; Kohonen-Corish, M. R.; O'Toole, S. A.; Cooper, W. A.
HISTOPATHOLOGY 70 (3) :402-411, 2017 10.1111/his.13076
Massive parallel sequencing of solid tumours - challenges and opportunities for pathologists
Harris, G.; O'Toole, S.; George, P.; Browett, P.; Print, C.
HISTOPATHOLOGY 70 (1) :123-133, 2017 10.1111/his.13067