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224 items matching your search terms.
OpenAccess publication Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation
Hoy, A. J.;Bruce, C. R.;Cederberg, A.;Turner, N.;James, D. E.;Cooney, G. J.;Kraegen, E. W. :
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 293 (5) :E1358-64, 2007
OpenAccess publication Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression
Cleasby, M. E.;Reinten, T. A.;Cooney, G. J.;James, D. E.;Kraegen, E. W. :
MOLECULAR ENDOCRINOLOGY 21 (1) :215-28, 2007
OpenAccess publication Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans
Wang, Y.;Lam, K. S.;Kraegen, E. W.;Sweeney, G.;Zhang, J.;Tso, A. W.;Chow, W. S.;Wat, N. M.;Xu, J. Y.;Hoo, R. L.;Xu, A. :
CLINICAL CHEMISTRY 53 (1) :34-41, 2007
OpenAccess publication Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats
Kraegen, E. W.;Saha, A. K.;Preston, E.;Wilks, D.;Hoy, A. J.;Cooney, G. J.;Ruderman, N. B. :
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 290 (3) :E471-9, 2006
Rosiglitazone treatment enhances acute AMP-activated protein kinase-mediated muscle and adipose tissue glucose uptake in high-fat-fed rats
Ye, J. M.;Dzamko, N.;Hoy, A. J.;Iglesias, M. A.;Kemp, B.;Kraegen, E. :
DIABETES 55 (10) :2797-804, 2006
OpenAccess publication Oral administration of glucose promotes intracellular partitioning of fatty acid toward storage in white but not in red muscle
Fosgerau, K.;Fledelius, C.;Pedersen, K. E.;Kristensen, J. B.;Daugaard, J. R.;Iglesias, M. A.;Kraegen, E. W.;Furler, S. M. :
JOURNAL OF ENDOCRINOLOGY 190 (3) :651-8, 2006
Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
Lee, Y. S.;Kim, W. S.;Kim, K. H.;Yoon, M. J.;Cho, H. J.;Shen, Y.;Ye, J. M.;Lee, C. H.;Oh, W. K.;Kim, C. T.;Hohnen-Behrens, C.;Gosby, A.;Kraegen, E. W.;James, D. E.;Kim, J. B. :
DIABETES 55 (8) :2256-64, 2006
Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells and rodent liver in vivo
Parkes, H. A.;Preston, E.;Wilks, D.;Ballesteros, M.;Carpenter, L.;Wood, L.;Kraegen, E. W.;Furler, S. M.;Cooney, G. J. :
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 291 (4) :E737-44, 2006
Acute bidirectional manipulation of muscle glucose uptake by in vivo electrotransfer of constructs targeting glucose transporter genes
Cleasby, M. E.;Davey, J. R.;Reinten, T. A.;Graham, M. W.;James, D. E.;Kraegen, E. W.;Cooney, G. J. :
DIABETES 54 (9) :2702-11, 2005
Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms
Cleasby, M. E.;Dzamko, N.;Hegarty, B. D.;Cooney, G. J.;Kraegen, E. W.;Ye, J. M. :
DIABETES 53 (12) :3258-66, 2004
Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin
Ye, J. M.;Dzamko, N.;Cleasby, M. E.;Hegarty, B. D.;Furler, S. M.;Cooney, G. J.;Kraegen, E. W. :
DIABETOLOGIA 47 (7) :1306-13, 2004
Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo
Saha, A. K.;Avilucea, P. R.;Ye, J. M.;Assifi, M. M.;Kraegen, E. W.;Ruderman, N. B. :
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 314 (2) :580-5, 2004
Peroxisome proliferator-activated receptor (PPAR) activation induces tissue-specific effects on fatty acid uptake and metabolism in vivo--a study using the novel PPARalpha/gamma agonist tesaglitazar
Hegarty, B. D.;Furler, S. M.;Oakes, N. D.;Kraegen, E. W.;Cooney, G. J. :
ENDOCRINOLOGY 145 (7) :3158-64, 2004
AMP-activated protein kinase activation by AICAR increases both muscle fatty acid and glucose uptake in white muscle of insulin-resistant rats in vivo
Iglesias, M. A.;Furler, S. M.;Cooney, G. J.;Kraegen, E. W.;Ye, J. M. :
DIABETES 53 (7) :1649-54, 2004
Minireview: malonyl CoA, AMP-activated protein kinase, and adiposity
Ruderman, N. B.;Saha, A. K.;Kraegen, E. W. :
ENDOCRINOLOGY 144 (12) :5166-71, 2003
The role of intramuscular lipid in insulin resistance
Hegarty, B. D.;Furler, S. M.;Ye, J.;Cooney, G. J.;Kraegen, E. W. :
ACTA PHYSIOL SCAND 178 (4) :373-83, 2003