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172 items matching your search terms.
Human inborn errors of immunity to herpes viruses
Jouanguy, E.; Beziat, V.; Mogensen, T. H.; Casanova, J. L.; Tangye, S. G.; Zhang, S. Y.
CURRENT OPINION IN IMMUNOLOGY 62 :106-122, 2020 https://doi.org/10.1016/j.coi.2020.01.004
Regulation of the germinal center and humoral immunity by interleukin-21
Tangye, S. G.; Ma, C. S.
JOURNAL OF EXPERIMENTAL MEDICINE 217 (1) :e20191638, 2020 10.1084/jem.20191638
It's that time of year-APRIL promotes humoral immunity in humans
Tangye, S. G.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 146 (5) :1013-1015, 2020 10.1016/j.jaci.2020.09.005
Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-beta
Li, J.; Ritelli, M.; Ma, C. S.; Rao, G.; Habib, T.; Corvilain, E.; Bougarn, S.; Cypowyj, S.; Grodecka, L.; Levy, R.; Beziat, V.; Shang, L.; Payne, K.; Avery, D. T.; Migaud, M.; Boucherit, S.; Boughorbel, S.; Guennoun, A.; Chrabieh, M.; Rapaport, F.; Bigio, B.; Itan, Y.; Boisson, B.; Cormier-Daire, V.; Syx, D.; Malfait, F.; Zoppi, N.; Abel, L.; Freiberger, T.; Dietz, H. C.; Marr, N.; Tangye, S. G.; Colombi, M.; Casanova, J. L.; Puel, A.
Science Immunology 4 (41) :eaax7965, 2019 10.1126/sciimmunol.aax7965
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
Zammit, N. W.; Siggs, O. M.; Gray, P. E.; Horikawa, K.; Langley, D. B.; Walters, S. N.; Daley, S. R.; Loetsch, C.; Warren, J.; Yap, J. Y.; Cultrone, D.; Russell, A.; Malle, E. K.; Villanueva, J. E.; Cowley, M. J.; Gayevskiy, V.; Dinger, M. E.; Brink, R.; Zahra, D.; Chaudhri, G.; Karupiah, G.; Whittle, B.; Roots, C.; Bertram, E.; Yamada, M.; Jeelall, Y.; Enders, A.; Clifton, B. E.; Mabbitt, P. D.; Jackson, C. J.; Watson, S. R.; Jenne, C. N.; Lanier, L. L.; Wiltshire, T.; Spitzer, M. H.; Nolan, G. P.; Schmitz, F.; Aderem, A.; Porebski, B. T.; Buckle, A. M.; Abbott, D. W.; Ziegler, J. B.; Craig, M. E.; Benitez-Aguirre, P.; Teo, J.; Tangye, S. G.; King, C.; Wong, M.; Cox, M. P.; Phung, W.; Tang, J.; Sandoval, W.; Wertz, I. E.; Christ, D.; Goodnow, C. C.; Grey, S. T.
NATURE IMMUNOLOGY 20 (10) :1299-1310, 2019 10.1038/s41590-019-0492-0
Flow Cytometric-Based Analysis of Defects in Lymphocyte Differentiation and Function Due to Inborn Errors of Immunity
Ma, C. S.; Tangye, S. G.
Frontiers in Immunology 10 :2108, 2019 10.3389/fimmu.2019.02108
A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance
Khourieh, J.; Rao, G.; Habib, T.; Avery, D. T.; Lefevre-Utile, A.; Chandesris, M. O.; Belkadi, A.; Chrabieh, M.; Alwaseem, H.; Grandin, V.; Sarrot-Reynauld, F.; Senechal, A.; Lortholary, O.; Kong, X. F.; Boisson-Dupuis, S.; Picard, C.; Puel, A.; Beziat, V.; Zhang, Q.; Abel, L.; Molina, H.; Marr, N.; Tangye, S. G.; Casanova, J. L.; Boisson, B.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (33) :16463-16472, 2019 10.1073/pnas.1901409116
The FOXP3Delta2 isoform supports Treg cell development and protects against severe IPEX syndrome
Frith, K.; Joly, A. L.; Ma, C. S.; Tangye, S. G.; Lohse, Z.; Seitz, C.; Verge, C. F.; Andersson, J.; Gray, P.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 144 (1) :317-320, 2019 10.1016/j.jaci.2019.03.003
Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4(+) T cells
Bier, J.; Rao, G.; Payne, K.; Brigden, H.; French, E.; Pelham, S. J.; Lau, A.; Lenthall, H.; Edwards, E. S. J.; Smart, J. M.; Cole, T. S.; Choo, S.; Joshi, A. Y.; Abraham, R. S.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; Holland, S. M.; Notarangelo, L. D.; Uzel, G.; Ma, C. S.; Brink, R.; Tangye, S. G.; Deenick, E. K.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 144 (1) :236-253, 2019 10.1016/j.jaci.2019.01.033
B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects
Moran, I.; Avery, D. T.; Payne, K.; Lenthall, H.; Davies, E. G.; Burns, S.; Ip, W.; Oleastro, M. M.; Reisli, I.; Guner, S.; Keles, S.; Notarangelo, L.; Deenick, E. K.; Goodnow, C. C.; Zahra, D.; Brink, R.; Circa; Wong, M.; Tangye, S. G.; Ma, C. S.; Phan, T. G.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 143 (6) :2302-2305, 2019 10.1016/j.jaci.2019.02.010
B cell-intrinsic requirement for STK4 in humoral immunity in mice and humans
Moran, I.; Avery, D. T.; Payne, K.; Lenthall, H.; Davies, E. G.; Burns, S.; Ip, W.; Oleastro, M. M.; Reisli, I.; Guner, S.; Keles, S.; Notarangelo, L.; Deenick, E. K.; Goodnow, C. C.; Zahra, D.; Brink, R.; Circa; Wong, M.; Tangye, S. G.; Ma, C. S.; Phan, T. G.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 143 (6) :2302-2305, 2019 10.1016/j.jaci.2019.02.010
Human CD8(+) T cell cross-reactivity across influenza A, B and C viruses
Koutsakos, M.; Illing, P. T.; Nguyen, T. H. O.; Mifsud, N. A.; Crawford, J. C.; Rizzetto, S.; Eltahla, A. A.; Clemens, E. B.; Sant, S.; Chua, B. Y.; Wong, C. Y.; Allen, E. K.; Teng, D.; Dash, P.; Boyd, D. F.; Grzelak, L.; Zeng, W.; Hurt, A. C.; Barr, I.; Rockman, S.; Jackson, D. C.; Kotsimbos, T. C.; Cheng, A. C.; Richards, M.; Westall, G. P.; Loudovaris, T.; Mannering, S. I.; Elliott, M.; Tangye, S. G.; Wakim, L. M.; Rossjohn, J.; Vijaykrishna, D.; Luciani, F.; Thomas, P. G.; Gras, S.; Purcell, A. W.; Kedzierska, K.
NATURE IMMUNOLOGY 20 (5) :613-625, 2019 10.1038/s41590-019-0320-6
Human inborn errors of the actin cytoskeleton affecting immunity: way beyond WAS and WIP
Tangye, S. G.; Bucciol, G.; de Las Casas, J. M.; Pillay, B.; Ma, C. S.; Moens, L.; Meyts, I.
IMMUNOLOGY AND CELL BIOLOGY 97 (4) :389-402, 2019 10.1111/imcb.12243
Hematopoietic stem cell transplant effectively rescues lymphocyte differentiation and function in DOCK8-deficient patients
Pillay, B. A.; Avery, D. T.; Smart, J. M.; Cole, T.; Choo, S.; Chan, D.; Gray, P. E.; Frith, K.; Mitchell, R.; Phan, T. G.; Wong, M.; Campbell, D. E.; Hsu, P.; Ziegler, J. B.; Peake, J.; Alvaro, F.; Picard, C.; Bustamante, J.; Neven, B.; Cant, A. J.; Uzel, G.; Arkwright, P. D.; Casanova, J. L.; Su, H. C.; Freeman, A. F.; Shah, N.; Hickstein, D. D.; Tangye, S. G.; Ma, C. S.
Journal of Clinical Investigation Insight 5 (11) 2019 10.1172/jci.insight.127527
Human DOCK2 Deficiency: Report of a Novel Mutation and Evidence for Neutrophil Dysfunction
Moens, L.; Gouwy, M.; Bosch, B.; Pastukhov, O.; Nieto-Patlan, A.; Siler, U.; Bucciol, G.; Mekahli, D.; Vermeulen, F.; Desmet, L.; Maebe, S.; Flipts, H.; Corveleyn, A.; Moshous, D.; Philippet, P.; Tangye, S. G.; Boisson, B.; Casanova, J. L.; Florkin, B.; Struyf, S.; Reichenbach, J.; Bustamante, J.; Notarangelo, L. D.; Meyts, I.
JOURNAL OF CLINICAL IMMUNOLOGY 39 (3) :298-308, 2019 10.1007/s10875-019-00603-w
Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD-the Goldilocks' Effect
Tangye, S. G.; Bier, J.; Lau, A.; Nguyen, T.; Uzel, G.; Deenick, E. K.
JOURNAL OF CLINICAL IMMUNOLOGY 39 (2) :148-158, 2019 10.1007/s10875-019-00612-9