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61 items matching your search terms.
OpenAccess publication Thyroid hormone receptor a mutation causes a severe and thyroxine-resistant skeletal dysplasia in female mice.
Bassett, J.H.; Boyde, A.; Zikmund, T.; Evans, H.; Croucher, P.I.; Zhu, X.; Won Park, J.; Cheng, S.Y.; Williams, G.R.
ENDOCRINOLOGY :en20132156, 2014
OpenAccess publication Zoledronic acid has differential anti-tumour activity in the pre-and post-menopausal bone microenvironment in vivo.
Ottewell, P.D.; Wang, N.; Brown, H.K.; Reeves, K.; Fowles, A.; Croucher, P.; Eaton, C.; Holen, I.
CLINICAL CANCER RESEARCH 20 (11) :2922-32, 2014 10.1158/1078-0432.CCR-13-1246
OpenAccess publication An N-ethyl-N-nitrosourea induced Corticotropin releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.
Bentley, L.; Esapa, C.T.; Nesbit, M.A.; Head, R.A.; Evans, H.; Lath, D.; Scudamore, C.L.; Hough, T.A.; Podrini, C.; Hannan, F.M.; Fraser, W.D.; Croucher, P.I.; Brown, M.A.; Brown, S.D.; Cox, R.D.; Thakker, R.V.
ENDOCRINOLOGY 155 (3) :908-22, 2014
OpenAccess publication Signaling between tumor cells and the host bone marrow microenvironment
Kovacic, N.; Croucher, P.I.; McDonald, M.
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.
Liu, J.Z.; Hov, J.R.; Folseraas, T.; Ellinghaus, E.; Rushbrook, S.M.; Doncheva, N.T.; Andreassen, O.A.; Weersma, R.K.; Weismuller, T.J.; Eksteen, B.; Invernizzi, P.; Hirschfield, G.M.; Gotthardt, D.N.; Pares, A.; Ellinghaus, D.; Shah, T.; Juran, B.D.; Milkiewicz, P.; Rust, C.; Schramm, C.; Muller, T.; Srivastava, B.; Dalekos, G.; Nothen, M.M.; Herms, S.; Winkelmann, J.; Mitrovic, M.; Braun, F.; Ponsioen, C.Y.; Croucher, P.J.; Sterneck, M.; Teufel, A.; Mason, A.L.; Saarela, J.; Leppa, V.; Dorfman, R.; Alvaro, D.; Floreani, A.; Onengut-Gumuscu, S.; Rich, S.S.; Thompson, W.K.; Schork, A.J.; Naess, S.; Thomsen, I.; Mayr, G.; Konig, I.R.; Hveem, K.; Cleynen, I.; Gutierrez-Achury, J.; Ricano-Ponce, I.; van Heel, D.; Bjornsson, E.; Sandford, R.N.; Durie, P.R.; Melum, E.; Vatn, M.H.; Silverberg, M.S.; Duerr, R.H.; Padyukov, L.; Brand, S.; Sans, M.; Annese, V.; Achkar, J.P.; Boberg, K.M.; Marshall, H.U.; Chazouilleres, O.; Bowlus, C.L.; Wijmenga, C.; Schrumpf, E.; Vermeire, S.; Albrecht, M.; The UK-PSCSC Consortium; The International IBD Genetics Consortium; Rioux, J.D.; Alexander, G.; Bergquist, A.; Cho, J.; Schreiber, S.; Manns, M.P.; Farkkila, M.; Dale, A.M.; Chapman, R.W.; Lazaridis, K.N.; The International PSC Study Group; Franke, A.; Anderson, C.A.; Karlsen, T.H.
NAT GENET 45 (6) :670-5, 2013
OpenAccess publication Bone mineral content and density
Esapa, C.T.; Bassett, J. H.; Evans, H.; Croucher, P.I.; Williams, G.R.; Thakker, R.V.;
Current Protocols in Mouse Biology 2 :365?400, 2012 10.1002/9780470942390.mo120124
OpenAccess publication A mouse model of early-onset renal failure due to a xanthine dehdrogenase nonsense mutation.
Piret, S.E.; Esapa, C.T.; Gorvin, C.M.; Head, R.; Loh, N.Y.; Devuyst, O.; Thomas, G.; Brown, S.D.M.; Brown, M.; Croucher, P.; Cox, R.; Thakker, R.V.
PLoS One 8 (9) :e45217, 2012
OpenAccess publication Soluble rank ligand produced by myeloma cells causes generalised bone loss in multiple myeloma.
Buckle, C.H.; De Leenheer, E.; Lawson, M.A.; Yong, K.; Rabin, N.; Perry, M.; Vanderkerken, K.; Croucher, P.I.
PLoS One 7 (8) :e41127, 2012 10.1371/journal.pone.0041127
OpenAccess publication Targeting tumour-initiating cells with trail based combination therapy ensures complete and lasting eradication of multiple myeloma tumours in vivo.
Vitovski, S.; Chantry, A.D.; Lawson, M.A.; Croucher, P.I.
PLoS One 7 (5) :e35830, 2012 10.1371/journal.pone.0035830
OpenAccess publication A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength
Baud'huin, M.; Solban, N.; Cornwall-Brady, M.; Sako, D.; Kawamoto, Y.; Liharska, K.; Lath, D.; Bouxsein, M.L.; Underwood, K.W.; Ucran, J.; Kumar, R.; Pobre, E.; Grinberg, A.V.; Seehra, J.; Canalis, E.; Pearsall, R.S.; Croucher, P.I.
OpenAccess publication Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength.
Bassett, J.H.D.; Gogakos, A.; White, J.K.; Evans, H.; Jacques, R.M.; Van der Spek, A.H.; Sanger Mouse Genetics Project; Ramirez-Solis, R.; Ryder, E.; Sunter, D.; Boyde, A.; Campbell, M.J.; Croucher, P.I.; Williams, G.R.
PLOS GENET 8 (8) :e1002858, 2012 10.1371/journal.pgen.1002858
OpenAccess publication Mice lacking the calcineurin enhibitor Rcan2 have an isolated defect of osteoblast function.
Bassett, J.H.D.; Logan, J.G.; Boyde, A.; Cheung, M.S.; Evans, H.; Croucher, P.; Sun, X.; Xu, S.; Murata, Y.; Williams, G.R.
ENDOCRINOLOGY 153 (7) :3537-48, 2012 10.1210/en.2011-1814
OpenAccess publication A mouse with an N-Ethyl-N-Nitrosourea (ENU) induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis
Esapa, C. T.; Head, R. A.; Jeyabalan, J.; Evans, H.; Hough, T. A.; Cheeseman, M. T.; McNally, E. G.; Carr, A. J.; Thomas, G. P.; Brown, M. A.; Croucher, P. I.; Brown, S. D.; Cox, R. D.; Thakker, R. V.;
PLoS One 7 (8) :e43205, 2012